Corneal regeneration using epithelial, stromal, and endothelial precursor cells based on epigenetical control.

• Project/Area Number: 23689072
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Single-year Grants
• Research Field: Ophthalmology
• Research Institution: Tokyo Women's Medical University (2012-2013); The University of Tokyo (2011)
• Principal Investigator: MIMURA Tatsuya 東京女子医科大学, 医学部, 講師 (70463867)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥27,300,000 (Direct Cost: ¥21,000,000、Indirect Cost: ¥6,300,000); Fiscal Year 2013: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000); Fiscal Year 2012: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000); Fiscal Year 2011: ¥11,440,000 (Direct Cost: ¥8,800,000、Indirect Cost: ¥2,640,000)
• Keywords: 眼発生・再生医学 / エピジェネティクス / 角膜再生 / 角膜 / メチル化 / 幹細胞移植

Research Abstract

We examined cellular aging and epigenetical alteration in corneal cells. We obtaiined corneal cells from endothelium, stoma, and epithelum of various aged donor corneas. Additionally, we obtained progenitor cells from each corneal cell layer by sphere-forming assay. By comparing the methylation among donor age, we found the ratio of methylation was higher in the cell from oleder donor cornea compared with younger donor conreas.

Research Products

• [Journal Article] Specific IgE for wheat in tear fluid of patients with allergic conjunctivitis (2014)
  • Author(s): Mimura T, Yamagami S, Noma H, Kamei Y, Goto M, Kondo A, Matsubara M
  • Journal Title: Cutan Ocul Toxicol
• [Journal Article] Retinal neuroprotective effect of Sirtuins (2014)
  • Author(s): Mimura T, Noma H, Funatsu H, Kondo A, Matsubara M
  • Journal Title: JSM Ophthalmol Volume: 2(1) Pages: 1016-1016
• [Journal Article] Retinal neuroprotective effect of Sirtuins. (2014)
  • Author(s): Mimura T, Noma H, Funatsu H, Kondo A, Matsubara M.
  • Journal Title: JSM Ophthalmol Volume: 2(1) Pages: 1016-1016
  • Peer Reviewed
• [Journal Article] Relationship between total tear IgE and specific serum IgE in autumnal allergic conjunctivitis (2013)
  • Author(s): Mimura T, Usui T, Yamagami S, Miyai T, Amano S
  • Journal Title: Cornea Volume: 32(1) Pages: 14-9
• [Journal Article] Bilateral eyelid erythema associated with false eyelash glue (2013)
  • Author(s): Mimura T
  • Journal Title: Cutaneous and Ocular Toxicology Volume: 32(1) Pages: 89-90
• [Journal Article] Association of inflammatory factors with macular edema in branch retinal vein occlusion (2013)
  • Author(s): Noma H, Mimura T, Eguchi S
  • Journal Title: JAMA Ophthalmol Volume: 131(2) Pages: 160-5
• [Journal Article] Retinal function and morphology in central retinal vein occlusion with macular oedema (2013)
  • Author(s): Noma H, Mimura T, Shimada K
  • Journal Title: Curr Eye Res Volume: 38(1) Pages: 143-9
• [Journal Article] Changes of inflammatory factors after intravitreal triamcinolone acetonide for macular edema with central retinal vein occlusion (2013)
  • Author(s): Noma H, Funatsu H, Mimura T
  • Journal Title: J Ocul Pharmacol Ther Volume: 29(3) Pages: 363-5
• [Journal Article] Visual function after pars plana vitrectomy in macular edema with branch retinal vein occlusion (2013)
  • Author(s): Noma H, Shimada K, Mimura T
  • Journal Title: Int Ophthalmol Volume: 33(3) Pages: 227-36
• [Journal Article] Corneal Endothelial Regeneration and Tissue Engineering (2013)
  • Author(s): Mimura T, Yamagami S, Amano S
  • Journal Title: Prog Retin Eye Res Volume: 35 Pages: 1-17
• [Journal Article] Changes of macular sensitivity and morphology after pars plana vitrectomy for macular edema with central retinal vein occlusion : a case series (2013)
  • Author(s): Noma H, Mimura T, Shimada K
  • Journal Title: BMC Ophthalmol Volume: 13(1) Pages: 2-2
• [Journal Article] Epigenetic regulation of retinal stem cells (2013)
  • Author(s): Mimura T, Noma H, Funatsu H
  • Journal Title: International Journal of Stem Cell Research and Transplantation (IJST) Volume: 103 Pages: 1-2
• [Journal Article] Influence of axial length on conjunctivochalasis (2013)
  • Author(s): Mimura T, Yamagami S, Kamei Y, Goto M, Matsubara M
  • Journal Title: Cornea Volume: 32(8) Pages: 1126-30
• [Journal Article] Influence of pars plana vitrectomy on macular sensitivity and morphology in patients with branch retinal vein occlusion and serous retinal detachment (2013)
  • Author(s): Noma H, Funatsu H, Shimada K, Mimura T
  • Journal Title: Ophthalmic Surg Lasers Imaging Retina Volume: 44(2) Pages: 160-7
• [Journal Article] Influence of retinal ischemia on macular function after pars plana vitrectomy for macular edema with branch retinal vein occlusion (2013)
  • Author(s): Noma H, Shimada K, Mimura T
  • Journal Title: Int Ophthalmol Volume: (Epub ahead of print)
• [Journal Article] Unilateral macular edema with central retinal vein occlusion in systemic lupus erythematosus : a case report (2013)
  • Author(s): Noma H, Shimizu H, Mimura T
  • Journal Title: Clin Ophthalmol Volume: 7 Pages: 865-867
• [Journal Article] Specific IgE in tear fluid and features of allergic conjunctivitis (2013)
  • Author(s): Mimura T, Yamagami S, Kamei Y, Goto M, Matsubara M
  • Journal Title: Curr Eye Res Volume: 38(9) Pages: 917-25
• [Journal Article] Next-generation sequencers : what can we learn? (2013)
  • Author(s): Mimura T, Noma H, Funatsu H, Yamagami S
  • Journal Title: J Bioanal Biomed Volume: 5(2) Pages: 1-3
• [Journal Article] The role of SIRT1 in ocular aging (2013)
  • Author(s): Mimura T, Kaji Y, Noma H, Funatsu H, Okamoto S
  • Journal Title: Exp Eye Res Volume: 116C Pages: 17-26
• [Journal Article] Aqueous soluble vascular endothelial growth factor receptor-2 in macular edema with branch retinal vein occlusion (2013)
  • Author(s): Noma H, Mimura T
  • Journal Title: Curr Eye Res
• [Journal Article] Aqueous flare and inflammatory factors in macular edema with central retinal vein occlusion : a case series (2013)
  • Author(s): Noma H, Mimura T, Tatsugawa M, Shimada K
  • Journal Title: BMC Ophthalmol Volume: 13(1) Pages: 78-78
• [Journal Article] Corneal endothelial regeneration and tissue engineering (2013)
  • Author(s): Mimura T, Yamagami S, Amano S.
  • Journal Title: Prog Retin Eye Res Volume: 35 Pages: 1
  • DOI: 10.1016/j.preteyeres.2013.01.003
  • URL: https://pure.teikyo.jp/en/publications/5a136e88-50db-4a05-840a-7dbdacf76a13
  • Peer Reviewed
• [Journal Article] Epigenetic regulation of retinal stem cells. (2013)
  • Author(s): Mimura T, Noma H, Funatsu H.
  • Journal Title: International Journal of Stem Cell Research and Transplantation Volume: 103 Pages: 1-2
  • Peer Reviewed
• [Journal Article] Next-generation sequencers: What can we learn? (2013)
  • Author(s): Mimura T, Noma H, Funatsu H, Yamagami S.
  • Journal Title: J Bioanal Biomed Volume: 5 Issue: 2 Pages: 1-3
  • DOI: 10.4172/1948-593x.1000e113
  • Peer Reviewed
• [Journal Article] The role of SIRT1 in ocular aging (2013)
  • Author(s): Mimura T, Kaji Y, Noma H, Funatsu H, Okamoto S.
  • Journal Title: Exp Eye Res Volume: 116 Pages: 17
  • DOI: 10.1016/j.exer.2013.07.017
  • URL: https://localhost/en/publications/9b2c743a-2178-4739-95ed-a4bb812dd4bc
  • Peer Reviewed
• [Journal Article] Vascular endothelial growth factor and Interleukin-6 are correlated with serous retinal detachment in central retinal vein occlusion (2012)
  • Author(s): Noma H, Funatsu H, Mimura T
  • Journal Title: Curr Eye Res Volume: 37(1) Pages: 62-7
• [Journal Article] Vitreous inflammatory factors and macular oedema (2012)
  • Author(s): Funatsu H, Noma H, Mimura T, Eguchi S
  • Journal Title: Br J Ophthalmol Volume: 96(2) Pages: 302-4
• [Journal Article] Conjunctivochalasis : associations with pinguecula in a hospital-based study (2012)
  • Author(s): Mimura T, Mori M, Obata H, Usui T, Yamagami S, Funatsu H, Noma H, Amano S
  • Journal Title: Acta Ophthalmol Volume: 90(8) Pages: 773-782
• [Journal Article] Pinguecula and diabetes mellitus (2012)
  • Author(s): Mimura T, Obata H, Usui T, Mori M, Yamagami S, Funatsu H, Noma H, Amano S
  • Journal Title: Cornea Volume: 31(3) Pages: 264-8
• [Journal Article] Vitreous Inflammatory Factors and Serous Macular Detachment in Branch Retinal Vein Occlusion (2012)
  • Author(s): Noma H, Funatsu H, Mimura T, Tatsugawa M, Shimada K, Eguchi S
  • Journal Title: Retina Volume: 32(1) Pages: 86-91
• [Journal Article] Inflammatory factors in major and macular branch retinal vein occlusion (2012)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K
  • Journal Title: Ophthalmologica Volume: 227(3) Pages: 146-52
• [Journal Article] Vascular endothelial growth factor receptor-2 in macular oedema with retinal vein occlusion (2012)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S
  • Journal Title: Ophthalmic Res Volume: 48(1) Pages: 56-58
• [Journal Article] Bilateral choroidal detachment after cord blood stem cell transplantation in an adult patient with acute myeloid leukemia (2012)
  • Author(s): Mimura T, Nakashizuka T, Kami J, Kohmura M, Sato S, Dou K, Mori M
  • Journal Title: Int Ophthalmol Volume: 32(4) Pages: 379-81
• [Journal Article] Functional-morphological changes after intravitreal injection of triamcinolone acetonide for macular edema with branch retinal vein occlusion (2012)
  • Author(s): Noma H, Funatsu H, Mimura T, Shimada K
  • Journal Title: J Ocul Pharmacol Ther Volume: 28(3) Pages: 231-6
• [Journal Article] Relation between Total Tear IgE and Severity of Acute Seasonal Allergic Conjunctivitis (2012)
  • Author(s): Mimura T, Usui T, Yamagami S, Miyai T, Amano S
  • Journal Title: Curr Eye Res Volume: 37(10) Pages: 864-70
• [Journal Article] Pigment epithelium-derived factor is related to macular microcirculation in patients with macular edema and branch retinal vein occlusion (2012)
  • Author(s): Noma H, Funatsu H, Mimura T
  • Journal Title: Int Ophthalmol Volume: 32(5) Pages: 485-9
• [Journal Article] Macular sensitivity and morphology after intravitreal injection of triamcinolone acetonide for macular edema with branch retinal vein occlusion (2012)
  • Author(s): Noma H, Funatsu H, Mimura T, Shimada K
  • Journal Title: Retina Volume: 32(9) Pages: 1844-52
• [Journal Article] Perifoveal Microcirculation in Macular Oedema with Retinal Vein Occlusion (2012)
  • Author(s): Noma H, Funatsu H, Mimura T, Shimada K
  • Journal Title: Open Ophthalmol J Volume: 6 Pages: 63-64
• [Journal Article] Comparison of the efficacy of intravitreal triamcinolone acetonide for cystoid macular edema with versus without serous retinal detachment in branch retinal vein occlusion : influence on macular sensitivity and morphology (2012)
  • Author(s): Noma H, Funatsu H, Mimura T, Shimada K
  • Journal Title: BMC Ophthalmol Volume: 12(1) Pages: 39-39
  • NAID: 120007164939
• [Journal Article] Association of electroretinographic parameters and inflammatory factors in branch retinal vein occlusion with macular oedema (2012)
  • Author(s): Noma H, Funatsu H, Mimura T
  • Journal Title: Br J Ophthalmol Volume: 96(12) Pages: 1489-93
• [Journal Article] Development of surgical treatment for vitreous disease (2012)
  • Author(s): Mimura T, Noma H, Funatsu H
  • Journal Title: Surgical Science Volume: 3(11) Pages: 507-513
• [Journal Article] Tissue engineering of corneal endothelium (2012)
  • Author(s): Mimura T, Yokoo S, Yamagami S
  • Journal Title: J. Funct. Biomater Volume: 3(4) Pages: 726-744
• [Journal Article] Use of the femtosecond laser for cataract surgery with intraocular lens implantation (2012)
  • Author(s): Mimura T, Yamazaki K
  • Journal Title: J Transplant Technol Res Volume: 2
• [Journal Article] Macular sensitivity and morphology after intravitreal injection of triamcinolone acetonide for macular edema secondary to central retinal vein occlusion (2012)
  • Author(s): Noma H, Mimura T
  • Journal Title: Clin Ophthalmol Volume: 6 Pages: 1901-6
• [Journal Article] Foveal Sensitivity and Morphology in Major and Macular Branch Retinal Vein Occlusion (2012)
  • Author(s): Noma H, Shimada K, Mimura T
  • Journal Title: Open Ophthalmol J Volume: 6 Pages: 104-9
• [Journal Article] Visual Accommodation and Advances in Management of Presbyopia (2012)
  • Author(s): Mimura T, Noma H, Yamagami S
  • Journal Title: Biol Syst Volume: 2 Pages: 107-107
• [Journal Article] Vitreous inflammatory factors and macular oedema (2012)
  • Author(s): Funatsu H, Noma H, Mimura T, Eguchi S
  • Journal Title: Br J Ophthalmol Volume: 96 Issue: 2 Pages: 302
  • DOI: 10.1136/bjo.2010.181222
  • Peer Reviewed
• [Journal Article] Pinguecula and diabetes mellitus (2012)
  • Author(s): Mimura T, Obata H, Usui T, Mori M, Yamagami S, Funatsu H, Noma H, Amano S
  • Journal Title: Cornea Volume: 31 Issue: 3 Pages: 264
  • DOI: 10.1097/ico.0b013e3182254170
  • URL: https://pure.teikyo.jp/en/publications/1432058f-036d-4aba-aea5-c6c1c15eba7a
  • Peer Reviewed
• [Journal Article] Tissue engineering of corneal endothelium. (2012)
  • Author(s): Mimura T, Yokoo S, Yamagami S.
  • Journal Title: J. Funct. Biomater. Volume: 3 Issue: 4 Pages: 726-744
  • DOI: 10.3390/jfb3040726
  • Peer Reviewed
• [Journal Article] Visual function and serous retinal detachment in patients with branch retinal vein occlusion and macular edema : a case series (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Shimada K
  • Journal Title: BMC Ophthalmol Volume: 11(1) Pages: 29-29
  • NAID: 120007164937
• [Journal Article] Recent advances and history of vitreous surgery (2011)
  • Author(s): Mimura T, Nakashizuka T, Mori M
  • Journal Title: Journal of Healthcare Engineering Volume: 2(4)
• [Journal Article] Influence of vitreous factors after vitrectomy for macular edema in patients with central retinal vein occlusion (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K
  • Journal Title: Int Ophthalmol Volume: 31(5) Pages: 393-402
• [Journal Article] Prospects for Descemet stripping automated endothelial keratoplasty using cultured human corneal endothelial cells (2011)
  • Author(s): Mimura T, Yamagami S, Yokoo S, Usui T, Amano S
  • Journal Title: J Transplant Technol Res S2-001
• [Journal Article] Vitreous inflammatory factors and serous retinal detachment in central retinal vein occlusion : a case control series (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S
  • Journal Title: J Inflamm (Lond) Volume: 8(1) Pages: 38-38
  • NAID: 120007164938
• [Journal Article] Laser treatment of giant iris cyst with nanophthalmos (2011)
  • Author(s): Honda N, Mimura T, Hotehama A, Usui T, Sugisaki K, Fukuoka S, Amano S
  • Journal Title: Int Ophthalmol Volume: 31(1) Pages: 17-20
• [Journal Article] Relationship between total tear and serum IgE in allergic conjunctivitis (2011)
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Yamamoto H, Aixinjueluo W, Amano S
  • Journal Title: Int Arch Allergy Immunol Volume: 154(4) Pages: 349-52
• [Journal Article] Rapid immunochromatographic measurement of specific tear IgE in moderate to severe cases of allergic conjunctivitis with immfast check J1 in the spring (2011)
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Amano S
  • Journal Title: Cornea Volume: 30(5) Pages: 524-7
• [Journal Article] Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in macular edema with central retinal vein occlusion (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K, Hori S
  • Journal Title: Curr Eye Res Volume: 36(3) Pages: 256-63
• [Journal Article] Severity and determinants of pinguecula in a hospital-based population (2011)
  • Author(s): Mimura T, Usui T, Obata H, Yamagami S, Mori M, Funatsu H, Noma H, Dou K, Amano S
  • Journal Title: Eye Contact Lens Volume: 37(1) Pages: 31-35
• [Journal Article] Sudden onset of amantadine-induced reversible bilateral corneal edema in an elderly patient : Case report and literature review (2011)
  • Author(s): Hotehama A, Mimura T, Usui T, Kawashima H, Amano S
  • Journal Title: Jpn J Ophthalmol Volume: 55(1) Pages: 71-74
  • NAID: 10029020683
• [Journal Article] Relation between total tear IgE and specific serum IgE in seasonal allergic conjunctivitis (2011)
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Yamamoto H, Aixinjueluo W, Amano S
  • Journal Title: Cornea Volume: 30(7) Pages: 790-5
• [Journal Article] Role of soluble vascular endothelial growth factor receptor-2 in macular oedema with central retinal vein occlusion (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K
  • Journal Title: Br J Ophthalmol Volume: 95(6) Pages: 788-92
• [Journal Article] Visual prognosis and vitreous molecules after vitrectomy for macular edema with branch retinal vein occlusion (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguchi S, Shimada K
  • Journal Title: Clin Ophthalmol Volume: 5 Pages: 223-9
• [Journal Article] Relationship between conjunctivochalasis and refractive error (2011)
  • Author(s): Mimura T, Usui T, Yamagami S, Funatsu H, Noma H, Toyono T, Mori M, Amano S
  • Journal Title: Eye Contact Lens Volume: 37(2) Pages: 71-8
• [Journal Article] Specific tear IgE in patients with moderate-to-severe autumnal allergic conjunctivitis (2011)
  • Author(s): Mimura T, Usui T, Mori M, Funatsu H, Noma H, Amano S
  • Journal Title: Int Arch Allergy Immunol Volume: 156(4) Pages: 381-386
• [Journal Article] Functional-morphological correlates in patients with branch retinal vein occlusion and macular edema (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Harino S, Shimada K
  • Journal Title: Retina Volume: 31(10) Pages: 2102-8
• [Journal Article] Effect of trabeculectomy on ocular and corneal higher order aberrations (2011)
  • Author(s): Fukuoka S, Amano S, Honda N, Mimura T, Usui T, Araie M
  • Journal Title: Jpn J Ophthalmol Volume: 55(5) Pages: 460-6
  • NAID: 10029688809
• [Journal Article] Soluble vascular endothelial growth factor receptor-2 and inflammatory factors in macular edema with branch retinal vein occlusion (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Eguch S, Hori S
  • Journal Title: Am J Ophthalmol Volume: 152(4)
• [Journal Article] Asymptomatic subconjunctival entrapment of a cilium (2011)
  • Author(s): Mimura T, Nakashizuka T, Kami J, Kohmura M, Sato S, Dou K, Mori M
  • Journal Title: Int Ophthalmol Volume: 31(4) Pages: 325-6
• [Journal Article] Influence of ischemia on visual function in patients with branch retinal vein occlusion and macular edema (2011)
  • Author(s): Noma H, Funatsu H, Mimura T, Shimada K
  • Journal Title: Clin Ophthalmol Volume: 5
• [Journal Article] Association of electroretinogram and morphological findings in branch retinal vein occlusion with macular edema (2011)
  • Author(s): Noma H, Funatsu H, Harino S, Sugawara T, Mimura T, Shimada K
  • Journal Title: Doc Ophthalmol Volume: 123(2) Pages: 83-91
• [Journal Article] Conjunctivochalasis: Associations with pinguecula in a hospital-based study (2011)
  • Author(s): Mimura T, Mori M, Obata H, Usui T, Yamagami S, Funatsu H, Noma H, Amano S
  • Journal Title: Acta Ophthalmol Volume: 90 Issue: 8 Pages: 773
  • DOI: 10.1111/j.1755-3768.2011.02161.x
  • Peer Reviewed
• [Journal Article] Prospects for Descemet stripping automated endothelial keratoplasty using cultured human corneal endothelial cells (2011)
  • Author(s): Mimura T, Yamagami S, Yokoo, S, Usui T, Amano S
  • Journal Title: J Transplant Technol Res Volume: S2 Issue: S2 Pages: 1-1
  • DOI: 10.4172/2161-0991.s2-001
  • Peer Reviewed
• [Journal Article] Measurement of Specific Tear IgE With ImmunoCAP Rapid
  • Author(s): Mimura T, Yamagami S, Kamei Y, Goto M, Kondo A, Matsubara M
  • Journal Title: Journal of Investigational Allergology and Clinical Immunology Volume: (in press)
• [Journal Article] Shimada Pentraxin 3 and other inflammatory factors in central retinal vein occlusion and macular edema
  • Author(s): Noma H, Mimura T, Masahara H
  • Journal Title: Retina Volume: (in press)
• [Journal Article] Conjunctival sensitization to hydrolyzed wheat protein in facial soap
  • Author(s): Mimura T, Noma H, Yamagami S
  • Journal Title: J Investig Allergol Clin Immunol Volume: (in press)
• [Journal Article] Shimada Role of inflammation in macular edema with branch retinal vein occlusion
  • Author(s): Noma H, Funatsu H, Mimura T
  • Journal Title: Curr Eye Res Volume: (in press)
• [Journal Article] Association of electroretinogram and morphological findings in central retinal vein occlusion with macular edema
  • Author(s): Noma H, Mimura T, Kuse M, Shimada K
  • Journal Title: Clin Ophthalmol Volume: (in press)
• [Journal Article] Vascular endothelial growth factor and its soluble receptors-1 and -2 in iris neovascularization and neovascular glaucoma
  • Author(s): Noma H, Mimura T, Yasuda K, Shimura M
  • Journal Title: Ophthalmologica Volume: (in press)
• [Presentation] 角膜内皮の老化と再生 (2013)
  • Author(s): 三村達哉
  • Organizer: 第80回東京女子医大東医療センター眼科医局講演会特別講演
  • Place of Presentation: 東京
  • Year and Date: 2013-10-12
• [Presentation] ヒト角膜内皮細胞の全ゲノム解析によるDNAメチル化プロファイル角膜カンファランス (2013)
  • Author(s): 三村達哉、中川卓、山上聡、天野史郎
  • Organizer: 第29回日本角膜移植学会
  • Place of Presentation: 南紀白浜
  • Year and Date: 2013-02-14
• [Presentation] 角膜内皮の老化と再生 (2013)
  • Author(s): 三村達哉
  • Organizer: 第80回東京女子医大 東医療センター 眼科医局講演会
  • Place of Presentation: 東京女子医科大学東医療センター
• [Presentation] 骨髄移植後寛解状態の悪性リンパ腫に認めたHHV-6による網膜分離症、網膜炎の一例 (2011)
  • Author(s): 寶一博、中静隆之、西田彩、幸村百理男、上順子、三村達哉、岸本修一、佐藤新兵、森樹郎
  • Organizer: 第66回日本臨床眼科学会
  • Place of Presentation: 東京
  • Year and Date: 2011-10-07
• [Presentation] コンタクトレンズ装用による結膜弛緩症、瞼裂斑、および結膜下出血 (2011)
  • Author(s): 三村達哉
  • Organizer: 第65回日本臨床眼科学会
  • Place of Presentation: 東京(招待講演)
  • Year and Date: 2011-10-07
• [Presentation] イムノキャップラピッドを用いた涙液中特異的IgEと皮膚プリックテストの比較
  • Author(s): 三村達哉、山上聡、臼井智彦、宮井尊史、天野史郎
  • Organizer: 第116回日本眼科学会総会
  • Place of Presentation: 東京国際フォーラム
• [Presentation] アレルギー性結膜炎患者涙液中の小麦特異的IgE
  • Author(s): 三村達哉、亀井裕子、五嶋摩理、近藤亜紀、松原正男
  • Organizer: 第66回日本臨床眼科学会
  • Place of Presentation: 国立京都国際会館・グランドプリンスホテル京都
• [Presentation] 細隙灯顕微鏡所見を正確にとるための解剖学・生理学
  • Author(s): 三村達哉
  • Organizer: 角結膜疾患診療ナビ 学術講演会
  • Place of Presentation: 東京ステーションホテル
  • Invited
• [Presentation] ヒト角膜内皮細胞の全ゲノム解析によるDNAメチル化プロファイル
  • Author(s): 三村達哉、中川卓、山上聡、天野史郎
  • Organizer: 角膜カンファランス2013
  • Place of Presentation: 和歌山県 南紀白浜
• [Presentation] Specific Tear IgE in Seasonal Allergic Conjunctivitis with ImmunoCAP Rapid
  • Author(s): Tatsuya Mimura, Satoru Yamagami, Tomohiko Usui, Takashi Miyai, Shiro Amano
  • Organizer: The Assosiation for Research in Vision and Ophthalmology
  • Place of Presentation: Greater Fort Lauderdale/Broward County Convention Center
• [Book] Transplantation of corneal stroma reconstructed with gelatin and multipotent precursor cells from corneal stroma(In : Daniel Eberli, editor. Regenerative Medicine and Tissue Engineering; From Cells to Organs)(ISBN 978-953-307-688-1) (2011)
  • Author(s): Mimura T, Tabata Y, Amano S
  • Publisher: InTech
• [Book] Regenerative Medicine and Tissue Engineering ; From Cells to Organs/Book 2 (ISBN 978-953-307-688-1) (2011)
  • Author(s): Mimura T, Tabata Y, Amano S
  • Publisher: Transplantation of corneal stroma reconstructed with gelatin and multipotent precursor cells from corneal stroma. In : Daniel Eberli, editor
• [Book] Corneal endothelial tissue bioengineering using cultured human corneal endothelial precursor cells(In : Jose A. Andrades, editor. Chapter 18, Regenerative Medicine and Tissue Engineering)(ISBN 978-953-51-1108-5)
  • Author(s): Mimura T, Yokoo S, Yamagami S
  • Publisher: InTech