• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Unification of three-type likelihood-inferences and its application development in Cox-type counting processes model under incomplete data

Research Project

Project/Area Number 23700336
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Statistical science
Research InstitutionHirosaki University

Principal Investigator

SUGIMOTO Tomoyuki  弘前大学, 理工学研究科, 准教授 (70324829)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords統計的推測 / 統計数学 / データ分析 / 生存時間解析 / 統計解析 / 点過程論 / 事象時間データ / 計数過程 / データ解析 / 漸近論 / 生存解析 / 確率過程 / Cox回帰 / 離散確率過程論 / 統計モデル
Research Abstract

In this research, we studied the statistical inference theory and statistical methods outstanding in several situations accompanied with incomplete data, in order to create further useful applications and developments of the Cox regression models, which are often used as a tool for data analysis to evaluate the effect of patient's treatment or prognosis factors statistically in the area of clinical medicine, and so on. We investigated the properties and roles on the three types of partial likelihoods, and their relationships to elucidate them in terms of theory and applications.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (24 results)

All 2013 2012 2011 Other

All Journal Article (12 results) (of which Peer Reviewed: 12 results) Presentation (10 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Asymptotic distribution of the nonparametric distribution estimator based on a martingale approach in doubly censored data2013

    • Author(s)
      Sugimoto, T
    • Journal Title

      Annals of the Institute of Statistical Mathematics

      Volume: Vol. 65(5) Issue: 5 Pages: 859-888

    • DOI

      10.1007/s10463-012-0395-4

    • NAID

      40019817780

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] A logrank test-based method for sizing clinical trials with two co-primary time-to-events endpoints2013

    • Author(s)
      Sugimoto T, Sozu T, Hamasaki T, Evans SR
    • Journal Title

      Biostatistics

      Volume: 14 Issue: 3 Pages: 409-421

    • DOI

      10.1093/biostatistics/kxs057

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] On consistencies of the profile likelihood estimators and their derivatives of the distribution function in doubly censored data2013

    • Author(s)
      Sugimoto, T
    • Journal Title

      Communications in Statistics -Theory and Methods

      Volume: 42 Issue: 15 Pages: 2741-2757

    • DOI

      10.1080/03610926.2011.581781

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sample size determination for clinical trials with co-primary outcomes. Exponential event-times2013

    • Author(s)
      Hamasaki T, Sugimoto T, Evans SR, Sozu T
    • Journal Title

      Pharmaceutical Statistics

      Volume: 12 Issue: 1 Pages: 28-34

    • DOI

      10.1002/pst.1545

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] On an inverse formula of a tridiagonal matrix2012

    • Author(s)
      Sugimoto, T
    • Journal Title

      Operators and Matrices

      Volume: 6 Issue: 3 Pages: 465-480

    • DOI

      10.7153/oam-06-30

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] A convenient formula for sample size calculations in clinical trials with multiple co-primary continuous endpoints2012

    • Author(s)
      Sugimoto T, Sozu T, Hamasaki T
    • Journal Title

      Pharmaceutical Statistics

      Volume: 11 Issue: 2 Pages: 118-128

    • DOI

      10.1002/pst.505

    • Related Report
      2013 Final Research Report 2012 Research-status Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Elevation of Sema4A impiicates T helper cell skewing and the efficacy of interferon-β therapy in multiple sclerosis2012

    • Author(s)
      中辻裕司
    • Journal Title

      Journal of Immunology

      Volume: 188 Issue: 10 Pages: 4858-65

    • DOI

      10.4049/jimmunol.1102023

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Sample size determination in clinical trials with multiple co-primary endpoints including mixed continuous and binary variables2012

    • Author(s)
      Sozu T, Sugimoto T, Hamasaki T
    • Journal Title

      Biometrical Journal

      Volume: 54 Issue: 5 Pages: 716-729

    • DOI

      10.1002/bimj.201100221

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Survival benefit of bursectomy in patients with resectable gastric cancer: interim analysis results of a randomized controlled trial2012

    • Author(s)
      Fujita J, Kurokawa Y, Sugimoto T, Miyashiro I, Iijima S, Kimura Y, Takiguchi S, Fujiwara Y, Mori M, Doki Y.
    • Journal Title

      Gastric Cancer

      Volume: 15 Issue: 1 Pages: 42-48

    • DOI

      10.1007/s10120-011-0058-9

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] A Wald-type variance estimation for the nonparametric distribution estimators for doubly censored data2011

    • Author(s)
      Sugimoto, T
    • Journal Title

      Annals of the Institute of Statistical Mathematics

      Volume: 63 Issue: 4 Pages: 645-670

    • DOI

      10.1007/s10463-009-0251-3

    • NAID

      40019008505

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 地域がん登録資料に基づくがん患者の治癒確率の推定2011

    • Author(s)
      伊藤ゆり・杉本知之
    • Journal Title

      統計数理

      Volume: 59 Pages: 287-300

    • NAID

      120006020391

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Sample size determination in superiority clinical trials with multiple co-primary correlated endpoints2011

    • Author(s)
      Sozu T, Sugimoto T, Hamasaki T
    • Journal Title

      Journal of Biopharmaceutical Statistics

      Volume: 21 Issue: 4 Pages: 650-668

    • DOI

      10.1080/10543406.2011.551329

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Relative survival trees with application to cancer registry data2013

    • Author(s)
      Sugimoto T. & Ito Y
    • Organizer
      34th Annual conference of the International Society for Clinical Biostatistics, Abstract Book C4.1
    • Related Report
      2013 Final Research Report
  • [Presentation] Semiparametric maximum likelihood estimation for relative survival rate2013

    • Author(s)
      Komukai S., Sugimoto T., Hattori S. & Ito Y
    • Organizer
      34th Annual conference of the International Society for Clinical Biostatistics, Abstract Book C4.4
    • Related Report
      2013 Final Research Report
  • [Presentation] Sample size considerations when using two time-to-event outcomes for comparing two interventions in clinical trials2013

    • Author(s)
      Hamasaki T., Sugimoto T., Sozu T. & Evans S.R.
    • Organizer
      ASA's Joint Statistical Meetings
    • Related Report
      2013 Final Research Report
  • [Presentation] Relative survival trees with application to cancer registry data2013

    • Author(s)
      Sugimoto, T., Ito, Y.
    • Organizer
      34th Annual conference of the International Society for Clinical Biostatistics
    • Place of Presentation
      Munich, Germany
    • Related Report
      2013 Annual Research Report
  • [Presentation] Semiparametric maximum likelihood estimation for relative survival rate2013

    • Author(s)
      Komukai, S., Sugimoto, T., Hattori, S., Ito, Y.
    • Organizer
      34th Annual conference of the International Society for Clinical Biostatistics
    • Place of Presentation
      Munich, Germany
    • Related Report
      2013 Annual Research Report
  • [Presentation] Sample size considerations when using two time-to-event outcomes for comparing two interventions in clinical trials2013

    • Author(s)
      Hamasaki, T., Sugimoto, T., Sozu, T., Evans, S.R.
    • Organizer
      ASA's Joint Statistical Meetings
    • Place of Presentation
      Montréal, Canada
    • Related Report
      2013 Annual Research Report
  • [Presentation] Sample size determination in clinical trials with multiple correlated endpoints2012

    • Author(s)
      Hamasaki, T., Sozu, T., Sugimoto, T. and Evans, S.R.
    • Organizer
      The 2012 Joint Statistical Meetings
    • Place of Presentation
      San Diego, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Sample size determination in group sequential trials with two co-primary endpoints2012

    • Author(s)
      Asakura, K., Hayashi, K., Sozu, T., Sugimoto, T. and Hamasaki, T.
    • Organizer
      The 26th International Biometric Conference
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2012 Research-status Report
  • [Presentation] 複数の主要評価変数の費用効率を考慮した臨床試験のデザイン2012

    • Author(s)
      寒水孝司・杉本知之・濱﨑俊光
    • Organizer
      2012年度統計関連学会連合大会
    • Place of Presentation
      北海道大学
    • Related Report
      2012 Research-status Report
  • [Presentation] Sample size determination in clinical trials with two correlated time-to-event endpoints2011

    • Author(s)
      Tomoyuki Sugimoto, Toshimitsu Hamasaki, Takashi Sozu
    • Organizer
      The 7th international conference on multiple comparison procedures
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2011 Research-status Report
  • [Book] 樹木構造接近法2013

    • Author(s)
      下川敏雄・杉本知之・後藤昌司
    • Total Pages
      228
    • Publisher
      共立出版
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Remarks]

    • URL

      http://www.st.hirosaki-u.ac.jp/~sugimoto/

    • Related Report
      2013 Final Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi