| Project/Area Number |
23700365
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Neuroscience in general
|
|---|
| Research Institution | University of Tsukuba |
|---|
Principal Investigator |
|
|---|
| Research Collaborator |
KANAHO Yasunori 筑波大学, 医学医療系, 教授 (00214437)
SUZUKI Atsushi 筑波大学, 大学院人間総合科学研究科, 博士課程学生
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | 発生 / 発達 / 再生神経科学 / 神経細胞 / 細胞骨格 / ホスファチジルエタノールアミン |
|---|
| Research Abstract |
We have examined whether and how phosphatidylethanolamine, a phospholipid consisting of the plasma membrane, is involved in neuronal morphogenesis. Our results indicated that the intramembranous movement (flip-flop movement) of phosphatidylethanolamine, which is induced by a type IV ATPase, controls neurite morphogenesis by organizing actin cytoskeleton in growth cones through the regulation of small G protein Cdc42.
|
