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Higher order auditory neural activities underlying the perception of sound continuity

Research Project

Project/Area Number 23700377
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Neuroscience in general
Research InstitutionUniversity of Yamanashi

Principal Investigator

QIN Ling  山梨大学, 医学工学総合研究部, 准教授 (20432156)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsauditory cortex / sound discrimination / spike activity / perception / free moving / chronic recording / sound discirmination / behavirol animal / neural activity / attention / auditory cortx / temporal code / rate code / neuralmetrics / acoustic perception / behavioral animal
Research Abstract

Previous studies on the neural functions of auditory cortex were commonly conducted on anesthetized or strained animals. In the present study, we for the first time used free moving cats. Cats were trained to perform a Go/NoGo behaving task to discriminate continuous and interrupted sounds. We then implanted multiple-channel electrodes into the primary auditory cortex and high order auditory cortices, and recorded the neural activities during the cats performed the task. By analyzing the relation between neural activities and behavioral responses, we revealed the neural response patterns correlating to the discrimination between continuous and interrupted sounds. Furthermore, we recorded the neural activities in various brain areas as the cats were actively discriminating the sounds and passively listening to the same sounds. By comparing the neural responses under the two conditions, we revealed the effects of auditory attention on various brain areas.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (16 results)

All 2013 2012 2011 Other

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (5 results) Remarks (3 results)

  • [Journal Article] Behavioral modulation of neural encoding of click-trains in the primary and nonprimary auditory cortex of cats2013

    • Author(s)
      Dong C, Qin L, Zhao Z, Zhong R, Sato Y
    • Journal Title

      J Neurosc

      Volume: 7;33(32) Pages: 13126-37

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of neural responses to cat meows and human vowels in the anterior and posterior auditory field of awake cats2013

    • Author(s)
      Ma H, Qin L, Dong C, Zhong R, Sato Y
    • Journal Title

      PLoS One

      Volume: 8(1)

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Behavioral Modulation of Neural Encoding of Click-Trains in2013

    • Author(s)
      Chao Dong, Ling Qin,Zhenling Zhao, Renjia Zhong, Yu Sato
    • Journal Title

      The Journal of Neuroscience,

      Volume: 33 Issue: 32 Pages: 13126-13137

    • DOI

      10.1523/jneurosci.1724-13.2013

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Correlation between neural discharges in cat primary auditorycortex and tone-detection behaviors2012

    • Author(s)
      Zhang X, Yang P, Dong C, Sato Y, Qin L
    • Journal Title

      Behav Brain Res.

      Volume: 232(1) Pages: 114-23

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chronic microstimulation of cat auditory cortex effective to evoke detection behaviors2012

    • Author(s)
      Wang J, Liu Y, Qin L, Chimoto S, Nakamoto K, Sato Y
    • Journal Title

      Neuroscience

      Volume: 206 Pages: 81-8

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Correlation between neural discharges in cat primary auditorycortex and tone-detection behaviors2012

    • Author(s)
      Zhang X, Yang P, Dong C, Sato Y, Qin L
    • Journal Title

      Behav Brain Res

      Volume: 232 Pages: 114-23

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Neural responses in the primary auditory cortex of freely behaving cats while discriminating fastand slow click-trains2011

    • Author(s)
      Dong C, Qin L, Liu Y, Zhang X, Sato Y
    • Journal Title

      PLoS One

      Volume: 6(10)

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural responses in the primary auditory cortex of freely behaving cats while discriminating fast and slow click-trains.2011

    • Author(s)
      Dong C, Qin L, Liu Y, Zhang X, Sato Y.
    • Journal Title

      PLoS One.

      Volume: 6(10)

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Neural processing of communication sounds in different areas of the auditory cortex of awake cats2012

    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2012-09-18
    • Related Report
      2013 Final Research Report
  • [Presentation] クリック音の知覚判別に関する大脳一次聴覚野の神経機構2012

    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      長野県松本
    • Year and Date
      2012-03-31
    • Related Report
      2013 Final Research Report
  • [Presentation] Neural processing of communication sounds in different areas of the auditory cortex of awake cats2012

    • Author(s)
      Ling Qin, Hanlu Ma, Chao Dong, Renjia Zhong and Yu Sato
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場 (愛知県)
    • Related Report
      2012 Research-status Report
  • [Presentation] Effects of engaging in an auditory task on the neural activities of the primary and non-primary auditory coteries2012

    • Author(s)
      Chao Dong, Hanlu Ma, Renjia Zhong Ling Qin and Yu Sato
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場 (愛知県)
    • Related Report
      2012 Research-status Report
  • [Presentation] クリック音の知覚判別に関する大脳一次聴覚野の神経機構

    • Author(s)
      Ling Qin, Chao Dong and Yu Sato
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      長野県松本文化会館
    • Related Report
      2011 Research-status Report
  • [Remarks] 研究室HP

    • URL

      http://www.med.yamanashi.ac.jp/basic/physio02/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 聴覚脳機能の研究

    • URL

      http://www.med.yamanashi.ac.jp/basic/physio02/

    • Related Report
      2012 Research-status Report
  • [Remarks]

    • URL

      http://www.med.yamanashi.ac.jp/basic/physio02/

    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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