| Project/Area Number |
23700399
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neuroscience in general
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| Research Institution | Keio University (2012)
The Institute of Physical and Chemical Research (2011) |
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Principal Investigator |
TAKATA Norio 慶應義塾大学, 医学部, 特任講師 (50415212)
|
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| Research Collaborator |
HIRASE Hajime 独立行政法人理化学研究所, 神経グリア回路研究チーム, チームリーダー (90392084)
YAHAGI Kazuko 独立行政法人理化学研究所, 神経グリア回路研究チーム, 技術員
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | グリア細胞 / アストロサイト / in vivo / 脳血流 / 大脳皮質 / マイネルト基底核 / ヒゲ / ２光子励起顕微鏡 / シナプス可塑性 / マウス / カルシウム / 光刺激 / オプトジェネティクス |
|---|
| Research Abstract |
Glial involvement in synaptic plasticity in vivo was investigated. Major findings are followings: astrocytes showed calcium activity upon the induction of cortical plasticity; extracellular D-serine concentration increased accompanying the glial activitie
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