Investigation of astrocytic involvement in the cortical plasiticity in vivo
| Project/Area Number |
23700399
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neuroscience in general
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| Research Institution | Keio University (2012)
The Institute of Physical and Chemical Research (2011) |
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Principal Investigator |
TAKATA Norio 慶應義塾大学, 医学部, 特任講師 (50415212)
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| Research Collaborator |
HIRASE Hajime 独立行政法人理化学研究所, 神経グリア回路研究チーム, チームリーダー (90392084)
YAHAGI Kazuko 独立行政法人理化学研究所, 神経グリア回路研究チーム, 技術員
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | グリア細胞 / アストロサイト / in vivo / 脳血流 / 大脳皮質 / マイネルト基底核 / ヒゲ / ２光子励起顕微鏡 / シナプス可塑性 / マウス / カルシウム / 光刺激 / オプトジェネティクス |
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| Research Abstract |
Glial involvement in synaptic plasticity in vivo was investigated. Major findings are followings: astrocytes showed calcium activity upon the induction of cortical plasticity; extracellular D-serine concentration increased accompanying the glial activitie
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Report
(3 results)
Research Products
(26 results)
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[Journal Article] Remodeling of monoplanar Purkinje cell dendrites during cerebellar circuit formation2011
Author(s)
Kaneko, M., Yamaguchi, K., Eiraku, M., Sato, M., Takata, N., Kiyohara, Y., Mishina, M., Hirase, H., Hashikawa, T. and Kengaku, M
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Journal Title
PLoS ONE
Volume: 6
Issue: 5
Pages: e20108-e20108
DOI
Related Report
Peer Reviewed
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