Analysis of NF-kB signaling in the pathogenesis of Rett syndrome
| Project/Area Number |
23700426
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Nerve anatomy/Neuropathology
|
|---|
| Research Institution | Keio University |
|---|
Principal Investigator |
KISHI Noriyuki 慶應義塾大学, 医学部, 特任助教 (30594882)
|
|---|
| Research Collaborator |
OKANO Hideyuki 慶應義塾大学, 医学部, 教授 (60160694)
OKUNO Misako 慶應義塾大学, 医学部, 研究員
JEFFREY D. Macklis ハーバード大学, 医学部, 教授
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | 脳発達障害 / レット症候群 / 自閉症 / MeCP2 / NF-ｋBシグナル / PCRアレイ / NF-kBシグナル |
|---|
| Research Abstract |
In this research project, we investigated the involvement of NF-kB signaling in the pathogenesis of Mecp2-null mice by PCR array analysis. Using PCR arrays that consisted of 84 NF-kB signaling-related genes, we compared gene expression profiles between wi
|
Report
(3 results)
Research Products
(20 results)
