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Single neuronal substrate responsible for emotions underlyingreward-seeking

Research Project

Project/Area Number 23700501
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Fusional social brain science
Research InstitutionUniversity of Tsukuba

Principal Investigator

MIZUHIKI Takashi  筑波大学, 医学医療系, 助教 (60463824)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords感性 / 情動 / 感情 / 島皮質 / 単一ニューロン活動 / 報酬 / モチベーション / 心拍数 / サル / 動機付け / 身体覚醒度
Research Abstract

It has been hypothesized that the emotion is embodied from psychological, behavioral and physical reactions elicited by reward. This is the first study that shows the correlation between behavioral and physical reactions under reward-guidedbehavior performed by macaque monkeys. Furthermore, the recordings from single neurons in monkey insulae during reward-seeking showed that the insulae responded to reward expectation. These results suggest that the interoception elicited by reward might provide a foundation for emotional and motivational reactions. These findings were reported in Journal of neurophysiology in 2012.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (3 results)

All 2012

All Journal Article (3 results) (of which Peer Reviewed: 3 results)

  • [Journal Article] Encoding of reward expectation by monkey anterior insular neurons.2012

    • Author(s)
      Mizuhiki T, Richmond BJ, Shidara M.
    • Journal Title

      Journal of Neurophysiology

      Volume: vol.107 Issue: 11 Pages: 2996-3007

    • DOI

      10.1152/jn.00282.2011

    • Related Report
      2012 Annual Research Report 2012 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] The influence of passband limitation on the waveform of extracellular action potential.2012

    • Author(s)
      Mizuhiki T, Inaba K, Setogawa T, Toda K, Ozaki S, Shidara M.
    • Journal Title

      Neuroscience Research

      Volume: vol.72(3) Issue: 3 Pages: 214-220

    • DOI

      10.1016/j.neures.2011.12.004

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The influence of passband limitation on the waveform of extracellular action potential.2012

    • Author(s)
      Mizuhiki T, Inaba K, Setogawa T, Toda K, Ozaki S, Shidara M.
    • Journal Title

      Neuroscience Research

      Volume: 72 Pages: 214-220

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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