| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Research Abstract |
The C57BL/6N strain is widely used as the genetic background for knockout mice generated by large-scale projects worldwide. In this study, we identified novel single nucleotide polymorphisms (SNPs) specific to the C57BL/6N strain and selected SNPs for genetic monitoring of C57BL/6N substrains. As a result, we confirmed a number of SNP loci that demonstrated genetic differences among C57BL/6N substrains. This SNP information will be useful for accurate genetic monitoring of the C57BL/6N congenic strain background.
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