Development of intracellular glycated products monitoring systems for cellular functional regulation.
| Project/Area Number |
23700545
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Tokyo University of Technology |
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Principal Investigator |
MIKAMI Akane (SAKAGUCHI Akane) 東京工科大学, 応用生物学部, 助教 (70469782)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 生体情報 / 計測 / 細胞機能制御 / 細胞内計測 / 糖尿病 / 糖化物 / 転写調節因子 / 生体情報・計測 |
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| Research Abstract |
Novel transcriptional regulators for intracellular glycated products monitoring and transcriptional regulation systems in mammalian cells have been investigated. A putative glycated product-responsive regulator (GprR) was cloned and found to function as GprR. A regulator based on the GprR was then designed as novel transcriptional regulator which allows intracellular GPs monitoring in mammalian cells.
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Report
(3 results)
Research Products
(13 results)
