| Project/Area Number |
23700555
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Biomedical engineering/Biological material science
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
SAKAI Takamasa 東京大学, 大学院・工学系研究科, 助教 (70456151)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | ハイドロゲル / Tetra-PEG ゲル / 医用構造材料 / 生分解性 / 高分子ゲル / Tetra-PEGゲル / 生体構造材料 / 生体材料 / 精密構造制御 |
|---|
| Research Abstract |
In order to apply Tetra-PEG gel for biomedical structural materials, we evaluated the biocompativility and drug releasing behavior, and introduced the biodegradability to Tetra-PEG gel. We confirmed the biocompatibility of raw material, gelation reaction, and formed gels. We investigated the release of model drugs from Tetra-PEG gels, and clarified the effect of mesh size on the drug releasing behavior. We designed the novel molecules and succeeded in the fabrication of biodegradable Tetra-PEG gels.
|
