Development of magnetic and fluid simulation for magnetic chromatography in prote i n separation

• Project/Area Number: 23700570
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Medical systems
• Research Institution: Hokkaido University
• Principal Investigator: NOGUCHI So 北海道大学, 大学院・情報科学研究科, 准教授 (30314735)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
• Keywords: 検査・診断システム / ナノ医用工学 / 磁気分離 / 磁場シミュレーション / 流体シミュレーション / 磁気クロマトグラフィー / 蛋白質分離

Research Abstract

Ihave developed an accurate simulation tool of magnetics andfluid-dynamics for designing magnetic columns in magnetic chromatography. ln developingthe multi-physics simulation tool considering magnetics and fluid dynamics, the largedifference between scale of protein, magnetic column, and magnet has to be taken intoaccount. The developed simulation tool can deal with plural kinds of protein.

Research Products

• [Journal Article] Magnetic Field and Fluid Flow Computation of Plural Kinds of Magnetic Particles for Magnetic Separation (2012)
  • Author(s): So Noguchi, SeokBeom Kim
  • Journal Title: IEEE Transactions on Magnetics Volume: vol.48,no.2 Pages: 523-526
  • Peer Reviewed
• [Journal Article] Magnetic Field and Fluid Flow Computation of Plural Kinds of Magnetic Particles for Magnetic Separation (2012)
  • Author(s): So Noguchi
  • Journal Title: IEEE Transactions on Magnetics Volume: 48 Issue: 2 Pages: 523-526
  • DOI: 10.1109/tmag.2011.2174207
  • Peer Reviewed
• [Journal Article] Simulation of Magnetic Fluid to Develop the Magnetic Chromatography for Magnetic Particle Separation (2011)
  • Author(s): So Noguchi, SeokBeom Kim
  • Journal Title: IEEE Transactions on Magnetics Volume: vol.47, no.10 Pages: 3947-3950
  • Peer Reviewed
• [Journal Article] lnvestigation of Novel Magnetic Chromatography With Ferromagnetic Nano-Wires for Ion Separation (2011)
  • Author(s): So Noguchi, SeokBeom Kim
  • Journal Title: IEEE Transactions on ApPIied Superconductivity Volume: vo1.21,no.3 Pages: 2068-2071
  • Peer Reviewed
• [Journal Article] Development of a Numerical Simulation Method for the Magnetic Separation of Magnetic Particles (2011)
  • Author(s): So Noguchi, SeokBeom Kim
  • Journal Title: IEEE Transactions on Magnetics Volume: vo1.47, no.5 Pages: 898-901
  • NAID: 120002989255
  • Peer Reviewed
• [Presentation] 磁気分離のための磁場 と磁性流体の連成数値解析 (2013)
  • Author(s): 野口聡,金錫範
  • Organizer: 電気学会全 国大会
  • Place of Presentation: 名古屋大学,名古屋
  • Year and Date: 2013-03-20
• [Presentation] Simulation of magnetic fluid flow with plural kinds of magnetic particles for magnetic particle separation (2012)
  • Author(s): So Noguchi, SeokBeom Kim
  • Organizer: IEEE International Magnetics Conference
  • Place of Presentation: Convention Center, Vancouver, Canada
  • Year and Date: 2012-05-09
• [Presentation] Magnetic Field Gradients and Fluid Flow Computation for Design of Magnetic Chromatography to Separate Magnetic Particles (2011)
  • Author(s): So Noguchi, SeokBeom Kim
  • Organizer: 18th Conference on the Computation of Electromagnetic Fields
  • Place of Presentation: Sydney Convention and Exhibition Centre, Sydney, Australia
  • Year and Date: 2011-07-14
• [Presentation] Simulation of magnetic fluid to develop the magnetic chromatography for magnetic particle separation (2011)
  • Author(s): So Noguchi, SeokBeom Kim
  • Organizer: IEEE International Magnetics Conference
  • Place of Presentation: Taipei International Convention Center, Taipei, Taiwan
  • Year and Date: 2011-04-28
• [Presentation] Simulation of magnetic fluid to develop the magnetic chromatography for magnetic particle separation (2011)
  • Author(s): So Noguchi, SeokBeom Kim
  • Organizer: International Magnetics Conference 2011
  • Place of Presentation: Taipei International Convention Center(Taiwan)
• [Presentation] Magnetic Field Gradients and Fluid Flow Computation for Design of Magnetic Chromatography to Separte Magnetic Particles (2011)
  • Author(s): So Noguchi, SeokBeom Kim
  • Organizer: 18th Conference on the Computation of Electromagnetic Fields
  • Place of Presentation: Sydney Convention and Exhibition Centre(Austraｌia)
• [Presentation] Simulation of magnetic fluid flow with plural kinds of magnetic particles for magnetic particle separation
  • Author(s): So Noguchi
  • Organizer: IEEE International Magnetics Conference
  • Place of Presentation: Convention Center (Vancouver, Canada)