Development of assessments for behavioral symptom linked to a dysfunctional ventromedial prefrontal cortex (VMPFC): Characterization of emotion on false memory production related to VMPFC
| Project/Area Number |
23700617
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Saitama Prefectural University |
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Principal Investigator |
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| Project Period (FY) |
2011-04-28 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 腹内側前頭前野 / 情動記憶 / 過誤記憶 / リハビリテーション / 作業療法 / 虚再認 / 腹内側前頭前皮質 / 内側前頭前野 / 情動 / 記憶 / モラル判断 / 行動神経科学 |
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| Outline of Final Research Achievements |
The present study aimed to investigate the effects of emotion on false memories involving roles of ventromedial prefrontal cortex (VMPFC) by evaluating two tasks of false recognition produced by emotion, one task of the Deese-Roediger-McDermott (DRM) paradigm and another task of the directed forgetting paradigm. Results of data on the DRM paradigm task showed that the number of false recognition in negative emotional stimuli is marginally increased than in neutral emotional stimuli. Results of data on the directed forgetting paradigm task revealed that the number of false recognition in negative emotional stimuli is a significant increase in comparison with neutral emotional stimuli, due to the decrease of attentional inhibition playing a role of dorsolateral prefrontal cortex in aging. These results represent an important step toward developing the evidence-based intervention strategy to improve behavioral symptom following damage to the VMPFC.
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Report
(6 results)
Research Products
(12 results)
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[Journal Article] 1.Neural Substrates of Cognitive Subtypes in Parkinson's Disease: A 3-Year Longitudinal Study2014
Author(s)
Shoji Y¸ Nishio Y, Baba T, Uchiyama M, Yokoi K, Ishioka T, Hosokai Y, Hirayama K, Fukuda H, Aoki M, Hasegawa T, Takeda A, Mori E.
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Journal Title
PLoS ONE
Volume: 9(10)
Issue: 10
Pages: e110547-e110547
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Hypometabolism in the supplementary and anterior cingulate cortices is related to dysphagia in Parkinson's disease: a cross-sectional and 3-year longitudinal cohort study.2013
Author(s)
Kikuchi A, Baba T, Hasegawa T, Kobayashi M, Sugeno N, Konno M, Miura E, Hosokai Y, Ishioka T, Nishio Y, Hirayama K, Suzuki K, Aoki M, Takahashi S, Fukuda H, Itoyama Y, Mori E, Takeda A.
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] Attentional set-shifting deficit in Parkinson's disease is associated with prefrontal dysfunction: an FDG-PET study2012
Author(s)
Sawada Y, Nishio Y, Suzuki K, Hirayama K, Takeda A, Hosokai Y, Ishioka T, Itoyama Y, Takahashi S, Fukuda H, Mori E
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Journal Title
Related Report
Peer Reviewed
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[Presentation] パーキンソン病における認知障害サブタイプの神経基盤: PETによる3年間縦断研究2014
Author(s)
庄司裕美子, 西尾慶之, 馬場徹, 内山信, 横井香代子, 石岡俊之, 細貝良行, 平山和美, 福田寛, 青木正志, 長谷川隆文, 武田篤, 森悦朗
Organizer
第16回日本ヒト脳機能マッピング学会
Place of Presentation
仙台
Related Report
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