| Project/Area Number |
23700622
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 神経筋電気刺激 / 心臓リハビリテーション / 骨格筋 / 心不全 / 慢性心不全 / 下肢筋力 / 運度療法 / 運動機能 / 運動療法 |
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| Research Abstract |
Neuromuscular electrical stimulation (NMES) is effective in preventing muscle weakness and the loss of skeletal muscle mass. However, the effects and safety of NMES in patients with acute decompensated heart failure or a left ventricular assist device (LVAD) are still unknown. We investigated the effects of NMES on muscular strength, vascular endothelial function, and peripheral circulation in these patients.
A single session of NMES improved endothelial function and peripheral circulation without excessive elevation of sympathetic nerve activity in patients with acute cardiovascular disease. In an LVAD-implanted CHF patient, two weeks of NMES improved muscle strength, balance function, and walking speed without affecting LVAD performance.
We conclude that short-term NMES intervention may improve muscular strength and vascular endothelial function with neither excessive elevation of sympathetic activity nor cardiovascular instability in patients with acute cardiovascular disease.
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