| Project/Area Number |
23700630
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Rehabilitation science/Welfare engineering
|
|---|
| Research Institution | Jikei University School of Medicine |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2012: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 脳卒中 / リハビリテーション / 反復性経頭蓋磁気刺激 / 急性期 / 片麻痺 / 経頭蓋磁気刺激 / 上肢麻痺 / 国際情報交流 |
|---|
| Research Abstract |
Recently, rTMS has been reported to improve motor function in chronic hemiparetic stroke patients. However, few studies have investigated the efficacy of rTMS introduced during the early phase of stroke.
Twenty-nine hemiparetic patients with acute stroke were randomly assigned into 3 groups: HF-rTMS group (10 Hz rTMS to the lesional hemisphere), LF-rTMS group (1 Hz rTMS to the non-lesional hemisphere), and sham stimulation group. The patients received sessions for 5 consecutive days. Comparison of the extent of improvement showed a more significant increase in motor function in the HF-rTMS group.
Fifty-eight hemiparetic patients with acute stroke were randomly assigned into 2 groups: HF-rTMS group and BL-rTMS (bilateral application of HF- and LF-rTMS) group. All patients received sessions of either HF-rTMS to the lesional hemisphere or BL-rTMS to both hemispheres for 5 consecutive days. Improvement of the affected upper limb was significantly greater in the BL-rTMS group.
|
