| Project/Area Number |
23700637
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Niigata University of Health and Welfare |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 医療 / 福祉,リハビリテーション,循環器,脳,リスク管理科学研究費助成事業(学術研究助成基金助成金)研究成果報告書 / 近赤外線分光法 / 大脳皮質 / 酸素化ヘモグロビン濃度 / 動脈スティフネス / 近赤外分光法 / 自転車エルゴメータ駆動 / 酸素化ヘモグロビン量 |
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| Research Abstract |
Near-infrared spectroscopy (NIRS) is a widely used non-invasive method to measure human brain activation based on cerebral hemodynamic response. NIRS has allowed researchers to visualize cortical activation patterns during human gait. However, systemic changes influence the measured signals. We determined the relationship between NIRS signals and skin blood flow (SBF) or blood pressure during dynamic movement. Healthy volunteers participated in this study. The pulse wave velocity was normal range. The oxyhemoglobin signal (O2Hb), SBF, and mean arterial pressure (MAP) were measured while the subjects performed exercise on a cycle ergometer at workloads corresponding to 30%, 50%, and 70% VO2peak. During the exercise, VO2, VCO2, HR, MAP and SBF were increased with increasing load on the cycle ergometer. However, O2Hb decreased during 70% VO2peak.
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