• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Effect of exercise training on formation of brite adipocytes within white adipose tissue

Research Project

Project/Area Number 23700778
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Sports science
Research InstitutionKyorin University

Principal Investigator

OGASAWARA Junetsu  杏林大学, 医学部, 助教 (20415110)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords褐色脂肪細胞 / 白色脂肪細胞 / 運動トレーニング / ブライト脂肪細胞 / トレーニング / 白色脂肪組織 / 誘導型褐色脂肪細胞 / 水泳運動 / UCP-1 / Cited 1 / SVフラクション / 分化 / PPARγ / PGC-1α / C/EBPβ
Research Abstract

The growing body of evidences has suggested that exposure of catecholamines give rise to brown-in-white adipocytes, which are referred to as brite adipocytes, within white adipose tissues. It has been widely accepted that continuous physical exercise exposes white adipocytes with catecholamines, suggesting the possibility that physical exercise would be expected to stimulating the formation of brite adipocytes in white adipose tissues.
Our result indicated that continuous running exercise promotes formation of brite adipocytes in rat subcutaneous white adipose tissue. Under this condition, hyperfunction of PPAR and/or its interaction with PRDM16 was shown to play a critical role in this mechanism.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (93 results)

All 2014 2013 2012 2011 Other

All Journal Article (31 results) (of which Peer Reviewed: 31 results,  Open Access: 1 results) Presentation (46 results) (of which Invited: 2 results) Book (16 results)

  • [Journal Article] ETAS, an enzyme-treated asparagus extract, attenuates amyloid β-induced cellular disorder in PC12 cells2014

    • Author(s)
      Ogasawara J, Ito T, Wakame K, Kitadate K, Sakurai T, Sato S, Ishibashi Y, Izawa T, Takahashi K, Ishida H, Takabatake I, Kizaki T & Ohno H
    • Journal Title

      Nat Prod Commun

      Volume: 9 Pages: 561-564

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of longterm exercise on cerebral function and the maintenance of concentration in the elderly2014

    • Author(s)
      Haga S, Sakurai T, Sato S, Sasahara M, Aita F, Esaki K, Toshinai K, Ueya E, Hashimoto N, Ogasawaea J, Kizaki T, Yoshinaga I, Sakurai T, Oh-ishi S, Ohno H & Takakuwa E
    • Journal Title

      J Exer Sports Orthop

      Volume: 1 Pages: 6-11

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] A circadian clock gene, Rev-erbα, modulates the inflammatory function of macrophages through the negative regulation of Ccl2 expression.2014

    • Author(s)
      Sato S, Sakurai T, Ogasawara J, Takahashi M, Izawa T, Imaizumi K, Taniguchi N, Ohno H, Kizaki T.
    • Journal Title

      J Immunol.

      Volume: 192 Issue: 1 Pages: 407-417

    • DOI

      10.4049/jimmunol.1301982

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Enzyme-treated Asparagus officinalis extract shows neuroprotective effects and attenuates cognitive impairment in senescence-accelerated mice2014

    • Author(s)
      Sakurai T, Ito T, Wakame K, Kitadate K, Arai T, Ogasawara J, Kizaki T, Sato S, Ishibashi Y, Fujiwara T, Akagawa K, Ishida H & Ohno H
    • Journal Title

      Nat Prod Commun

      Volume: 9 Pages: 101-106

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Enzyme-treated asparagus offcinalis extract shows neuroprotective effects and attenuates cognitive impairment in senescence-accelerated mice.2014

    • Author(s)
      Sakurai, T., et al.
    • Journal Title

      Nat Prod Commun

      Volume: 9 Pages: 101-106

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effects of long-term exercise on cerebral function and the maintenance of concentration in the elderly.2014

    • Author(s)
      Haga, S., et al.
    • Journal Title

      J Exer Sports Orthop

      Volume: 1 Pages: 6-11

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ETAS, an enzyme-treated asparagus extract, attenuates amyloid β-induced cellular disorder in PC12 cells.2014

    • Author(s)
      Ogasawara, J., et al.
    • Journal Title

      Nat Prod Commun

      Volume: 9 Pages: 561-564

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oligomerised lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells.2013

    • Author(s)
      Sakurai T, Kitadate K, Nishioka H, Fujii H, Ogasawara J, Kizaki T, Sato S, Fujiwara T, Akagawa K, Izawa T, Ohno H.
    • Journal Title

      Br J Nutr.

      Volume: 110 Issue: 9 Pages: 1549-1558

    • DOI

      10.1017/s000711451300086x

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Skeletal muscle oxygenation during the nagewaza kakari exercise in Judo2013

    • Author(s)
      Haga S, Kizaki T, Sato S, Takemasa T, Ezaki K, Ueya K, Aita F, Hashimoto N, Ogasawara J, Sakurai T, Hamaoka T, Katsumura T, Sakurai T & Ohno H
    • Journal Title

      SportSci Res

      Volume: 10 Pages: 233-241

    • URL

      http://waseda-sport.jp/paper/1225/1225.pdf

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of exercise training on obesity-induced dysregulated expression of adipokines in white adipose tissue.2013

    • Author(s)
      Sakurai T, Ogasawara J, Kizaki T, Sato S, Ishibashi Y, Takahashi M, Kobayashi O, Oh-Ishi S, Nagasawa J, Takahashi K, Ishida H, Izawa T, Ohno H.
    • Journal Title

      Int J Endocrinol.

      Volume: Article ID801743 Pages: 1-28

    • DOI

      10.1155/2013/801743

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of resistance exercise on intramuscular oxygenation and muscle fiber composition.2013

    • Author(s)
      Aita, F., et al.
    • Journal Title

      J. Sports Med. Doping Stud.

      Volume: 3 Issue: 03 Pages: 3-9

    • DOI

      10.4172/2161-0673.1000133

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 高所環境は肥満を改善する2013

    • Author(s)
      大野秀樹、木崎節子、櫻井拓也、小笠原準悦、佐藤章悟、石橋義永、宮澤伸子、長澤純一、野口いづみ、貫田宗男、荻原理江、村上和子、石田均、宮崎裕美、斎藤大蔵、小林靖、鈴木健二、人見嘉哲、中野法彦、大河原知水、大石修司、桜井智野風、井澤鉄也、白土健、今泉和彦、芳賀脩光
    • Journal Title

      登山医学

      Volume: 33 Pages: 167-171

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Skeletal muscle oxygenation during the nagewaza kakari exercise in judo.2013

    • Author(s)
      Haga, S., et al.
    • Journal Title

      Sport Sci Res

      Volume: 10 Pages: 233-241

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 高所環境は肥満を改善する.2013

    • Author(s)
      大野秀樹ほか
    • Journal Title

      登山医学

      Volume: 33 Pages: 167-171

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oligomerised lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress2013

    • Author(s)
      Sakurai T et al.
    • Journal Title

      Br. J. Nutr.

      Volume: 109

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Oligonol-induced degradation of perilipin 1 is regulated through lysosomal degradation machinery2012

    • Author(s)
      Ogasawara J, Kitadate K, Nishioka H, Fujii H, Sakurai T, Kizaki T, Izawa T, Ishida H & Ohno H
    • Journal Title

      Nat Prod Commun

      Volume: 7 Pages: 1193-1196

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Higher levels of ATGL are associated with exercise-induced enhancement of lipolysis in rat epididymal adipocytes.2012

    • Author(s)
      小笠原準悦
    • Journal Title

      PLoS ONE

      Volume: 7(7) Issue: 7 Pages: e40876-e40876

    • DOI

      10.1371/journal.pone.0040876

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Recent advances in the adaptations of adipose tissue to physical activity: Morphology and adipose tissue cellularity2012

    • Author(s)
      井澤鉄也
    • Journal Title

      The Journal of Physical Fitness and Sports Medicine

      Volume: 1 Issue: 3 Pages: 381-387

    • DOI

      10.7600/jpfsm.1.381

    • NAID

      10031158969

    • ISSN
      2186-8123, 2186-8131
    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of physical exercise on lipolysis in white adipocytes2012

    • Author(s)
      Ogasawara Junetsu
    • Journal Title

      The Journal of Physical Fitness and Sports Medicine

      Volume: 1 Issue: 2 Pages: 351-356

    • DOI

      10.7600/jpfsm.1.351

    • NAID

      10031158965

    • ISSN
      2186-8123, 2186-8131
    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Exercise training and the promotion of neurogenesis and neurite outgrowth in the hippocampus2012

    • Author(s)
      Sakurai, T., Ogasawara, J., Kizaki, T., Ishibashi, Y., Fujiwara, T., Akagawa, K., Izawa, T., Radák, Z. and Ohno, H
    • Journal Title

      The Journal of Physical Fitness and Sports Medicine

      Volume: 1 Issue: 2 Pages: 333-337

    • DOI

      10.7600/jpfsm.1.333

    • NAID

      10031158961

    • ISSN
      2186-8123, 2186-8131
    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effects of exercise on macrophage function2012

    • Author(s)
      Kizaki, T., Sato, S., Sakurai, T., Ogasawara, J., Imaizumi, K., Izawa, T., Nagasawa, J., Saitoh, D., Haga, S. and Ohno, H
    • Journal Title

      The Journal of Physical Fitness and Sports Medicine

      Volume: 1 Issue: 1 Pages: 113-123

    • DOI

      10.7600/jpfsm.1.113

    • NAID

      10031158932

    • ISSN
      2186-8123, 2186-8131
    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of exercise on HIF-1 and VEGF signaling2012

    • Author(s)
      Ohno, H., Shirato, K., Sakurai, T., Ogasawara, J., Sumitani, Y., Sato, S., Imaizumi, K., Ishida, H. and Kizaki, T
    • Journal Title

      The Journal of Physical Fitness and Sports Medicine

      Volume: 1 Issue: 1 Pages: 5-16

    • DOI

      10.7600/jpfsm.1.5

    • NAID

      10031158921

    • ISSN
      2186-8123, 2186-8131
    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preventive and improvement effects of exercise training and supplement intake in white adipose tissues on obesity and lifestyle-related diseases2012

    • Author(s)
      Sakurai, T., Ogasawara, J., Kizaki, Takahashi, K., Ishida, H., Miyazaki, H., Saitoh, D., Haga, S., Izawa, T. & Ohno, H.
    • Journal Title

      Environ. Health Prev. Med

      Volume: 17(in press) Issue: 5 Pages: 348-356

    • DOI

      10.1007/s12199-012-0271-0

    • NAID

      10031120507

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Oligonol-induced degradation of perilipin 1 is regulated through lysosomal degradation machinery.2012

    • Author(s)
      Ogasawara J et al.
    • Journal Title

      Nat. Prod. Commun.

      Volume: 7 Pages: 1193-1196

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Recent advances in the adaptations of adipose tissue to physical2012

    • Author(s)
      Izawa T et al.
    • Journal Title

      J. Phys. Fit. Sports Med.

      Volume: 1 Pages: 381-387

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of physical exercise on lipolysis in white adipocytes2012

    • Author(s)
      Ogasawara, J. et al.
    • Journal Title

      J. Phys. Fit. Sports Med.

      Volume: 1

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of exercise on HIF-1 and VEGF signaling.2012

    • Author(s)
      Ohno, H. et al.
    • Journal Title

      J. Phys. Fit. Sports Med.

      Volume: 1 Pages: 5-16

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] The effects of exercise on macrophage function.2012

    • Author(s)
      Kizaki, T. et al.
    • Journal Title

      J. Phys. Fit. Sports Med.

      Volume: 1 Pages: 113-124

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Exercise training and the promotion of neurogenesis and neurite outgrowth2012

    • Author(s)
      Sakurai, T. Ogasawara, J. et al.
    • Journal Title

      J. Phys. Fit. Sports Med.

      Volume: 1

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Involvement of leucine zipper transcription factor-like protein 1(Lztfl1) in the attenuation of cognitive impairment by exercise training2011

    • Author(s)
      Sakurai, T., Ogasawara, J., Kizaki, T., Ishibashi, Y., Fujiwara, T., Akagawa, K., Izawa, T., Oh-ishi, S., Haga, S. & Ohno, H.
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 416 Issue: 1-2 Pages: 125-129

    • DOI

      10.1016/j.bbrc.2011.11.008

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Voluntary exercise attenuates obesity-associated inflammation through ghrelin expressed in macrophages2011

    • Author(s)
      Kizaki, T., Maegawa, T., Sakurai, T., Ogasawara, J., Ookawara, T., Oh-ishi, S., Izawa, T., Haga, S. & Ohno, H.
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 413 Issue: 3 Pages: 454-459

    • DOI

      10.1016/j.bbrc.2011.08.117

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Presentation] 運動と脂肪細胞の働き2014

    • Author(s)
      小笠原準悦、櫻井拓也、石橋義永、木崎節子、白土健、今泉和彦、井澤鉄也、大野秀樹
    • Organizer
      第160回日本体力医学会関東地方会
    • Place of Presentation
      調布
    • Year and Date
      2014-03-08
    • Related Report
      2013 Final Research Report
  • [Presentation] 運動は骨格筋前駆細胞から褐色脂肪細胞への分化を誘導するか : 肥満予防・治療への応用2013

    • Author(s)
      小笠原準悦、櫻井拓也、木本紀代子、木崎節子、高橋和人、住谷由計、石田均、大野秀樹
    • Organizer
      第42回杏林医学会総会
    • Place of Presentation
      三鷹
    • Year and Date
      2013-11-16
    • Related Report
      2013 Final Research Report
  • [Presentation] 登山時の低酸素ストレス応答2013

    • Author(s)
      長澤純一、野口いづみ、笹尾真美、佐藤章悟、小笠原準悦、櫻井拓也、石橋義永、木崎節子、芳賀脩光、大野秀樹
    • Organizer
      第68回日本体力医学会大会
    • Place of Presentation
      東京
    • Year and Date
      2013-09-22
    • Related Report
      2013 Final Research Report
  • [Presentation] 時計遺伝子 Rev-erbαは MCP1遺伝子の発現を抑制しマクロファージ免疫機能を制御する2013

    • Author(s)
      佐藤章悟、木崎節子、櫻井拓也、小笠原準悦、石橋義永、長澤純一、桜井智野風、井澤鉄也、今泉和彦、芳賀脩光、大野秀樹
    • Organizer
      第68回日本体力医学会大会
    • Place of Presentation
      東京
    • Year and Date
      2013-09-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 水泳運動は前駆細胞からの褐色脂肪細胞化を促す2013

    • Author(s)
      小笠原準悦、櫻井拓也、木崎節子、佐藤章悟、石橋義永、井澤鉄也、宮崎裕美、斎藤大蔵、十枝内厚次、大石修司、芳賀脩光、大野秀樹
    • Organizer
      第68回日本体力医学会大会
    • Place of Presentation
      東京
    • Year and Date
      2013-09-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 脂肪組織および骨格筋組織における時計遺伝子と脂質代謝関連遺伝子の関連性2013

    • Author(s)
      加藤久詞、増田慎也、高倉久志、佐藤章悟、小笠原準悦、櫻井拓也、木崎節子、桜井智野風、大野秀樹、井澤鉄也
    • Organizer
      第68回日本体力医学会大会
    • Place of Presentation
      東京
    • Year and Date
      2013-09-21
    • Related Report
      2013 Final Research Report
  • [Presentation] Effect of frequent antioxidant supplementation on oxidative stress when climbing Mt Fuji2013

    • Author(s)
      Nagasawa J, Noguchi I, Sasao M, Sato S, Sakurai T, Ogasawara J, Ishibashi Y, Kizaki T & Ohno H
    • Organizer
      21st International Congress on Nutrition and Integrative Medicine
    • Place of Presentation
      Sapporo
    • Year and Date
      2013-07-28
    • Related Report
      2013 Final Research Report
  • [Presentation] Inhibitory effect of ETAS against amyloid beta-induced cellular disorder in PC12 cells2013

    • Author(s)
      Ogasawara J, Ito T, Takanari J, Sakurai T, Kizaki T, Sato S, Ishibashi Y, Nagasawa J, Saito D, Nakano N, Izawa T & Ohno H
    • Organizer
      21st International Congress on Nutrition and Integrative Medicine
    • Place of Presentation
      Sapporo
    • Year and Date
      2013-07-27
    • Related Report
      2013 Final Research Report
  • [Presentation] 運動は肥満による脂肪組織の線維化関連因子の発現増加を減弱させる2013

    • Author(s)
      櫻井拓也、小笠原準悦、木崎節子、長澤純一、芳賀脩光、大野秀樹
    • Organizer
      第21回日本運動生理学会大会
    • Place of Presentation
      川越
    • Year and Date
      2013-07-27
    • Related Report
      2013 Final Research Report
  • [Presentation] 持久性走トレーニングによる白色脂肪細胞の脂肪分解反応の亢進にはATGLの発現変化が関与する2013

    • Author(s)
      小笠原準悦、櫻井拓也、佐藤章悟、石橋義永、長澤純一、大石修司、芳賀脩光、井澤鉄也、木崎節子、大野秀樹
    • Organizer
      第158回日本体力医学会関東地方会
    • Place of Presentation
      新座
    • Year and Date
      2013-07-13
    • Related Report
      2013 Final Research Report
  • [Presentation] 水泳運動により誘導される肩甲骨周囲骨格筋群の褐色脂肪細胞化の検討2013

    • Author(s)
      小笠原準悦、櫻井拓也、木崎節子、佐藤章悟、石橋義永、井澤鉄也、斎藤大蔵、大石修司、芳賀脩光、大野秀樹
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢
    • Year and Date
      2013-03-25
    • Related Report
      2013 Final Research Report
  • [Presentation] 酸化処理アスパラガス抽出物は神経細胞において抗ストレス作用をもつ2013

    • Author(s)
      櫻井拓也、北舘健太郎、西岡浩、若命浩二、藤井創、小笠原準悦、木崎節子、藤原智徳、赤川公朗、大野秀樹
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢
    • Year and Date
      2013-03-25
    • Related Report
      2013 Final Research Report
  • [Presentation] 酸化処理アスパラガス抽出物は神経細胞障害を減弱させ、老化促進モデルマウスの認知機能障害を予防する2012

    • Author(s)
      櫻井拓也、小笠原準悦、木崎節子、木本紀代子、藤原智徳、赤川公朗、大野秀樹
    • Organizer
      第41回杏林医学会総会
    • Place of Presentation
      三鷹
    • Year and Date
      2012-11-17
    • Related Report
      2013 Final Research Report
  • [Presentation] The enzyme-treated Asparagus offcinalis extract shows anti-stress effects in neural cells and prevents cognitive impairment in senescenseaccelerated mice2012

    • Author(s)
      Sakurai T, Kitadate K, Nishioka H, Fujii H, Ogasawara J, Kizaki T, Sato S, Ishibashi Y, Fujiwara T, Akagawa K, Imaizumi K, Saitoh D, Izawa T & Ohno H
    • Organizer
      The 6th International Niigata Symposium on Diet and Health
    • Place of Presentation
      Niigata
    • Year and Date
      2012-10-17
    • Related Report
      2013 Final Research Report
  • [Presentation] 運動は肥満による脂肪組織のデルマトポンチン発現増加を減弱させる2012

    • Author(s)
      櫻井拓也、小笠原準悦、木崎節子、佐藤章悟、井澤鉄也、芳賀脩光、今泉和彦、大石修司、大野秀樹
    • Organizer
      第67回日本体力医学会大会
    • Place of Presentation
      岐阜
    • Year and Date
      2012-09-15
    • Related Report
      2013 Final Research Report
  • [Presentation] 水泳運動は骨格筋前駆細胞から褐色脂肪細胞への分化を促進する2012

    • Author(s)
      小笠原準悦、櫻井拓也、木崎節子、井澤鉄也、武政徹、芳賀脩光、長澤純一、大野秀樹
    • Organizer
      第20回日本運動生理学会大会
    • Place of Presentation
      つくば
    • Year and Date
      2012-07-29
    • Related Report
      2013 Final Research Report
  • [Presentation] The extract from stems of Asparagus offcinalis enhances the expression of heat shock proteins and shows anti-stress effects in neural cells2012

    • Author(s)
      Sakurai T, Kitadate K, Nishioka H, Wakame K, Fujii H, Ogasawara J, Kizaki T, Sato S, Ishibashi Y, Imaizumi K, Saitoh D, Izawa T & Ohno H
    • Organizer
      The 20th International Congress on Nutrition and Integrative Medicine
    • Place of Presentation
      Sapporo
    • Year and Date
      2012-07-22
    • Related Report
      2013 Final Research Report
  • [Presentation] 運動を用いた痩身への誘い~運動によって白色脂肪細胞では何が起こるのか~2012

    • Author(s)
      小笠原準悦、櫻井拓也、木崎節子、佐藤章悟、石橋義永、大野秀樹
    • Organizer
      平成24年度生理学若手研究フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2012-06-30
    • Related Report
      2013 Final Research Report
  • [Presentation] 運動するとなぜ痩せる?~白色脂肪細胞ではいったい何がおこるのか~2012

    • Author(s)
      小笠原準悦、櫻井拓也、木崎節子、井澤鉄也、大野秀樹
    • Organizer
      第14回日本体力医学会北海道地方会
    • Place of Presentation
      札幌
    • Year and Date
      2012-06-17
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] 水泳運動は骨格筋前駆細胞から褐色脂肪細胞への分化シグナルを促進する2012

    • Author(s)
      小笠原準悦、櫻井拓也、木崎節子、石橋義永、炭谷由計、井澤鉄也、石田均、鈴木健二、芳賀脩光、大野秀樹
    • Organizer
      第82回日本衛生学会学術総会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-25
    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Presentation] Oligonolは神経細胞において小胞体ストレス減弱作用をもつ2012

    • Author(s)
      櫻井拓也、北舘健太郎、西岡浩、若命浩二、藤井創、小笠原準悦、木崎節子、藤原智徳、赤川公朗、大野秀樹
    • Organizer
      第82回日本衛生学会学術総会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-25
    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Presentation] Oligonolは神経細胞において小胞体ストレスを減弱させる2011

    • Author(s)
      櫻井拓也、北舘健太郎、西岡浩、若命浩二、藤井創、小笠原準悦、石橋義永、木崎節子、藤原智徳、赤川公朗、炭谷由計、石田均、芳賀脩光、大野秀樹
    • Organizer
      第9回日本予防医学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-20
    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Presentation] 運動は骨格筋から褐色脂肪細胞への分化を活性化するか2011

    • Author(s)
      小笠原準悦、櫻井拓也、木崎節子、炭谷由計、高橋和人、石田均、木本紀代子、大野秀樹
    • Organizer
      第40回杏林医学会総会
    • Place of Presentation
      三鷹
    • Year and Date
      2011-11-19
    • Related Report
      2013 Final Research Report
  • [Presentation] Preventive effects of oligonol on cognitive impairment in senescence-accelerated mice and identification of its molecular target in hippocampus2011

    • Author(s)
      Sakurai T, Kidatate K, Nishioka H, Wakame K, Fujii H, Ogasawara J, Kizaki T, Ishibashi Y, Fujiwara T, Akagawa K, Nakano N, Izawa T & Ohno H
    • Organizer
      19st International Congress on Nutrition and Integrative Medicine
    • Place of Presentation
      Sapporo
    • Year and Date
      2011-10-16
    • Related Report
      2013 Final Research Report
  • [Presentation] 骨格筋から褐色脂肪細胞への分化機構に及ぼす寒冷曝露と水泳運動の効果2011

    • Author(s)
      小笠原準悦、櫻井拓也、木崎節子、石橋義永、炭谷由計、井澤鉄也、宮崎裕美、大石修司、芳賀脩光、大野秀樹
    • Organizer
      第66回日本体力医学会大会
    • Place of Presentation
      下関
    • Year and Date
      2011-09-17
    • Related Report
      2013 Final Research Report
  • [Presentation] 脂肪細胞の脂肪分解反応に及ぼす新規カテキン型ポリフェノール複合体Oligonolの効果2011

    • Author(s)
      小笠原準悦、北舘健太郎、西岡浩、藤井創、櫻井拓也、木崎節子、石橋義永、炭谷由計、石田均、井澤鉄也、大野秀樹
    • Organizer
      第21回体力・栄養・免疫学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-28
    • Related Report
      2013 Final Research Report
  • [Presentation] 運動は老化促進モデルマウスの認知機能障害を予防する2011

    • Author(s)
      櫻井拓也、小笠原準悦、木崎節子、井澤鉄也、長澤純一、芳賀脩光、大野秀樹
    • Organizer
      第19回日本運動生理学会大会
    • Place of Presentation
      徳島
    • Year and Date
      2011-08-26
    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Presentation] 脂肪細胞の脂肪分解反応に及ぼす新規カテキン型ポリフェノール複合体2011

    • Author(s)
      小笠原準悦ほか
    • Organizer
      第21回体力・栄養・免疫学会大会
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Presentation] 骨格筋から褐色脂肪細胞への分化機構に及ぼす寒冷曝露と水泳運動の効果2011

    • Author(s)
      小笠原準悦ほか
    • Organizer
      第66回日本体力医学会大会
    • Place of Presentation
      山口
    • Related Report
      2011 Research-status Report
  • [Presentation] Preventive effects of Oligonol on cognitive impairment in senescence-2011

    • Author(s)
      Sakurai, T. et al.
    • Organizer
      19th International Congress on Nutrition and Integrative Medicine
    • Place of Presentation
      Sapporo
    • Related Report
      2011 Research-status Report
  • [Presentation] 運動は骨格筋から褐色脂肪細胞への分化を活性化するか2011

    • Author(s)
      小笠原準悦ほか
    • Organizer
      第40回杏林医学会総会
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Presentation] 持久性走トレーニングによる白色脂肪細胞の脂肪分解反応の亢進にはATGLの発現変化が関与する.

    • Author(s)
      小笠原準悦ほか
    • Organizer
      第158回日本体力医学会関東地方会
    • Place of Presentation
      新座
    • Related Report
      2013 Annual Research Report
  • [Presentation] 運動は肥満による脂肪組織の線維化関連因子の発現増加を減弱させる.

    • Author(s)
      櫻井拓也ほか
    • Organizer
      第21回日本運動生理学会大会
    • Place of Presentation
      川越
    • Related Report
      2013 Annual Research Report
  • [Presentation] Inhibitory effect of ETAS against amyloid beta-induced cellular disorder in PC12 cells.

    • Author(s)
      Ogasawara, J., et al.
    • Organizer
      21st International Congress on Nutrition and Integrative Medicine
    • Place of Presentation
      Sapporo
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effect of frequent antioxidant supplementation on oxidative stress when climbing Mt. Fuji.

    • Author(s)
      Nagasawa, J., et al.
    • Organizer
      21st International Congress on Nutrition and Integrative Medicine
    • Place of Presentation
      Sapporo
    • Related Report
      2013 Annual Research Report
  • [Presentation] 脂肪組織および骨格筋組織における時計遺伝子と脂質代謝関連遺伝子の関連性.

    • Author(s)
      加藤久詞ほか
    • Organizer
      第68回日本体力医学会大会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 水泳運動は前駆細胞からの褐色脂肪細胞化を促す.

    • Author(s)
      小笠原準悦ほか
    • Organizer
      第68回日本体力医学会大会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 時計遺伝子Rev-erbαはMCP1遺伝子発現を抑制しマクロファージ免疫機能を制御する.

    • Author(s)
      佐藤章悟ほか
    • Organizer
      第68回日本体力医学会大会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 登山時の低酸素ストレス応答.

    • Author(s)
      長澤純一ほか
    • Organizer
      第68回日本体力医学会大会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 運動は骨格筋前駆細胞から褐色脂肪細胞への分化を誘導するか:肥満予防・治療への応用.

    • Author(s)
      小笠原準悦ほか
    • Organizer
      第42回杏林医学会総会
    • Place of Presentation
      三鷹
    • Related Report
      2013 Annual Research Report
  • [Presentation] A circadian clock gene Rev-erbα modulates inflammatory functions of macrophages through negative regulation of monocyte chemoattractant protein-1 expression.

    • Author(s)
      Kizaki, T., et al.
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      幕張
    • Related Report
      2013 Annual Research Report
  • [Presentation] 運動と脂肪細胞の働き.

    • Author(s)
      小笠原準悦ほか
    • Organizer
      第160回日本体力医学会関東地方会
    • Place of Presentation
      調布
    • Related Report
      2013 Annual Research Report
  • [Presentation] 運動するとなぜ痩せる?~白色脂肪細胞ではいったい何がおこるのか~.

    • Author(s)
      小笠原準悦ほか
    • Organizer
      第14回日本体力医学会北海道地方会
    • Place of Presentation
      北方圏学術情報センターPORTO(札幌)
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 運動を用いた痩身への誘い~運動によって白色脂肪細胞では何が起こるのか~.

    • Author(s)
      小笠原準悦ほか
    • Organizer
      平成24年度生理学若手研究フォーラム
    • Place of Presentation
      順天堂大学(東京)
    • Related Report
      2012 Research-status Report
  • [Presentation] 水泳運動は骨格筋前駆細胞から褐色脂肪細胞への分化を促進する.

    • Author(s)
      小笠原準悦ほか
    • Organizer
      第20回日本運動生理学会大会
    • Place of Presentation
      筑波大学大学会館(つくば)
    • Related Report
      2012 Research-status Report
  • [Presentation] 水泳運動により誘導される肩甲骨周囲骨格筋群の褐色脂肪細胞化の検討.

    • Author(s)
      小笠原準悦ほか
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢大学鶴間キャンパス
    • Related Report
      2012 Research-status Report
  • [Book] (第2章)褐色脂肪細胞の起源、増殖、分化.In:ここまでわかった燃える褐色脂肪組織の不思議、斎藤昌之、大野秀樹編2013

    • Author(s)
      小笠原準悦、井澤鉄也、大野秀樹
    • Publisher
      ナップ
    • Related Report
      2013 Final Research Report
  • [Book] 酵素処理アスパラガス茎熱水抽出物はアミロイドαにより誘導されるPC12細胞の細胞障害を抑制する.In:第21回統合医療機能性食品国際会議議事録2013

    • Author(s)
      小笠原準悦、伊藤知洋、高成準、櫻井拓也、木崎節子、佐藤章悟、石橋義永、長澤純一、斎藤大蔵、中野法彦、井澤鉄也、大野秀樹
    • Publisher
      AHCC研究会
    • Related Report
      2013 Final Research Report
  • [Book] 富士登山時の酸化ストレスに対する抗酸化剤頻回摂取の効果.In :第 21回統合医療機能性食品国際会議議事録2013

    • Author(s)
      長澤純一、野口いづみ、笹尾真美、佐藤章悟、櫻井拓也、小笠原準悦、石橋義永、木崎節子、大野秀樹
    • Publisher
      AHCC研究会
    • Related Report
      2013 Final Research Report
  • [Book] ここまでわかった燃える褐色脂肪組織の不思議2013

    • Author(s)
      小笠原準悦ほか
    • Total Pages
      158
    • Publisher
      ナップ
    • Related Report
      2013 Annual Research Report
  • [Book] 第21回統合医療機能性食品国際会議議事録2013

    • Author(s)
      小笠原準悦ほか
    • Total Pages
      127
    • Publisher
      AHCC研究会
    • Related Report
      2013 Annual Research Report
  • [Book] 第21回統合医療機能性食品国際会議議事録2013

    • Author(s)
      長澤純一ほか
    • Total Pages
      127
    • Publisher
      AHCC研究会
    • Related Report
      2013 Annual Research Report
  • [Book] アスパラガス茎抽出物は神経細胞の熱ショックタンパク質発現を誘導し、細胞障害を減弱させる.In :第20回統合医療機能性食品国際会議議事録2012

    • Author(s)
      櫻井拓也、北舘健太郎、西岡浩、若命浩二、藤井創、小笠原準悦、木崎節子、佐藤章悟、石橋義永、今泉和彦、斎藤大蔵、井澤鉄也
    • Publisher
      AHCC研究会
    • Related Report
      2013 Final Research Report
  • [Book] (第23章)燃焼系素材と運動.In :機能性食品素材と運動療法-生活習慣病予防と運動機能維持向上を目指して-.大澤俊彦、佐藤祐造監修2012

    • Author(s)
      大野秀樹、櫻井拓也、小笠原準悦、石橋義永、木崎節子
    • Publisher
      シーエムシー出版
    • Related Report
      2013 Final Research Report
  • [Book] 運動は肥満・糖尿病によるアルツハイマー病発症リスクを軽減するか.In :第27回健康医科学研究助成論文集2012

    • Author(s)
      櫻井拓也、小笠原準悦、木崎節子、石橋義永、藤原智徳、赤川公朗、井澤鉄也、芳賀脩光、大野秀樹
    • Publisher
      東京六法出版
    • Related Report
      2013 Final Research Report
  • [Book] 機能性食品素材と運動療法-生活習慣病予防と運動機能維持向上を目指して-2012

    • Author(s)
      大野秀樹ほか
    • Publisher
      シーエムシー出版
    • Related Report
      2011 Research-status Report
  • [Book] 明治安田厚生事業団第27回健康医科学研究助成論文集 平成22年度2012

    • Author(s)
      櫻井拓也ほか
    • Total Pages
      174
    • Publisher
      東京六法出版
    • Related Report
      2011 Research-status Report
  • [Book] エネルギースタンドとしての脂肪組織. In :脂肪組織のエクササイズバイオロジー一冊まるごと脂肪組織と運動の話.井澤鉄也・駒林隆夫編2011

    • Author(s)
      小笠原準悦、木崎節子、石橋義永、芳賀脩光、大野秀樹
    • Publisher
      ナップ
    • Related Report
      2013 Final Research Report
  • [Book] 内分泌器官としての脂肪組織:アデイポカインの分泌.In :脂肪組織のエクササイズバイオロジー一冊まるごと脂肪組織と運動の話.井澤鉄也・駒林隆夫編2011

    • Author(s)
      櫻井拓也、小笠原準悦、木崎節子、炭谷由計、石田均、大野秀樹
    • Publisher
      ナップ
    • Related Report
      2013 Final Research Report
  • [Book] Oligonolの老化促進モデルマウスの認知機能障害に対する予防効果と海馬におけるターゲット分子の同定.In :19回統合医療機能性食品国際会議議事録2011

    • Author(s)
      櫻井拓也、北舘健太郎、西岡浩、若命浩二、藤井創、小笠原準悦、木崎節子、石橋義永、藤原智徳、赤川公朗、中野法彦、井澤鉄也、大野秀樹
    • Publisher
      AHCC研究会
    • Related Report
      2013 Final Research Report
  • [Book] 脂肪組織のエクササイズバイオロジー 1冊まるごと脂肪組織と運動の話2011

    • Author(s)
      小笠原準悦ほか
    • Total Pages
      180
    • Publisher
      ナップ
    • Related Report
      2011 Research-status Report
  • [Book] 公益財団法人中冨健康科学振興財団第22回研究助成業績集 平成23年版2011

    • Author(s)
      小笠原準悦ほか
    • Total Pages
      158
    • Publisher
      医薬ジャーナル社
    • Related Report
      2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi