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The relationship between estrogen-synthesis related gene polymorphisms and exercise-induced reduction of arterial stiffness

Research Project

Project/Area Number 23700841
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Applied health science
Research InstitutionKokugakuin University

Principal Investigator

HAYASHI Koichiro  國學院大學, 人間開発学部, 准教授 (90433474)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords動脈硬化 / 身体活動 / 遺伝子多型 / エストロゲン
Research Abstract

In the present study, I examined the hypothesis that estrogen synthesis-related gene polymorphisms might influence arterial stiffening and the ability of regular exercise to improve arterial stiffness in Japanese healthy women. In rs4646 and rs1062033 pol

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (13 results)

All 2013 2012 2011

All Journal Article (3 results) (of which Peer Reviewed: 1 results) Presentation (10 results)

  • [Journal Article] Effects of regular aerobic exercise on post-exercise vagal reactivation in young female2013

    • Author(s)
      Mariko Nakamura, Koichiro Hayashi, Katsuji Aizawa, Noboru Mesaki, Ichiro Kono
    • Journal Title

      European Journal of Sport Science

      Volume: (in press)

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 女性の動脈硬化と運動(特集動脈硬化と運動・身体活動-予防・改善のための取り組み-2011

    • Author(s)
      林 貢一郎
    • Journal Title

      臨床スポーツ医学

      Volume: 28(12) Pages: 1353-1359

    • Related Report
      2012 Final Research Report
  • [Journal Article] 女性の動脈硬化と運動2011

    • Author(s)
      林 貢一郎
    • Journal Title

      臨床スポーツ医学

      Volume: 28 Pages: 1353-1359

    • Related Report
      2011 Research-status Report
  • [Presentation] Higher cardiorespiratory fitness attenuates arterial stiffening associated with the estrogen receptor-beta polymorphism in healthy women2013

    • Author(s)
      Koichiro Hayashi, Motoyuki Iemitsu, Haruka Murakami, Kiyoshi Sanada, Hiroshi Kawano, Yuko Gando, Noriko Tanaka, Motohiko Miyachi
    • Organizer
      18th annual congress of the European College of Sport Science
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2012 Annual Research Report
  • [Presentation] 閉経前女性におけるエストロゲン受容体α遺伝子多型と動脈硬化指数の関連2012

    • Author(s)
      林貢一郎,家光素行,村上晴香,真田樹義,山元健太,河野寛,宮地元彦
    • Organizer
      第67回日本体力医学会大会
    • Place of Presentation
      岐阜
    • Year and Date
      2012-09-16
    • Related Report
      2012 Final Research Report
  • [Presentation] 閉経前女性におけるエストロゲン受容体α遺伝子多型と動脈硬化指数の関連2012

    • Author(s)
      林貢一郎,家光素行,村上晴香,真田樹義,山元健太,河野寛,宮地元彦
    • Organizer
      第67回日本体力医学会大会
    • Place of Presentation
      岐阜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 「音楽を楽しむこと」は頚動脈伸展性を増大させる2011

    • Author(s)
      林貢一郎
    • Organizer
      第66回日本体力医学会大会
    • Place of Presentation
      下関
    • Year and Date
      2011-09-18
    • Related Report
      2012 Final Research Report
  • [Presentation] 動脈硬化に対する運動効果の個人差に関連する遺伝的要因:ゲノムワイド解析2011

    • Author(s)
      家光素行,村上晴香,真田樹義,河野寛,丸藤祐子,村上諒子,福典之,林貢一郎,宮地元彦
    • Organizer
      第66回日本体力医学会大会
    • Place of Presentation
      下関
    • Year and Date
      2011-09-17
    • Related Report
      2012 Final Research Report
  • [Presentation] Effects of menstrual cycle phase and exercise training type on central arterial compliance in young women.2011

    • Author(s)
      Koichiro Hayashi, Motohiko Miyachi, Jun Sugawara, Hidehiko Komine, Takashi Yokoi, Sho Onodera, Noboru Mesaki
    • Organizer
      16th Annual Meeting of the European College of Sport Science
    • Place of Presentation
      Liverpool, UK
    • Year and Date
      2011-07-06
    • Related Report
      2012 Final Research Report
  • [Presentation] Genome-wide association study of habitual exercise-induced improvement of arterial stiffness in Japanese adults2011

    • Author(s)
      Motoyuki Iemitsu, Haruka Murakami, Kiyoshi Sanada, Yuko Gando, Ryoko Kawakami, Noriyuki Fuku, Koichiro Hayashi, Motohiko Miyachi
    • Organizer
      58th Annual Meeting and 2nd World Congress on Exercise is Medicine of the American College of Sports Medicine
    • Place of Presentation
      Denver, Colorado,USA.
    • Year and Date
      2011-06-02
    • Related Report
      2012 Final Research Report
  • [Presentation] 動脈硬化に対する運動効果の個人差に関連する遺伝的要因:ゲノムワイド解析2011

    • Author(s)
      家光素行,村上晴香,真田樹義,河野寛,丸藤祐子,村上諒子,福典之,林貢一郎,宮地元彦
    • Organizer
      第66回 日本体力医学会大会
    • Place of Presentation
      山口県下関市
    • Related Report
      2011 Research-status Report
  • [Presentation] Effects of menstrual cycle phase and exercise training type on central arterial compliance in young women2011

    • Author(s)
      Koichiro Hayashi, Motohiko Miyachi, Jun Sugawara, Hidehiko Komine, Takashi Yokoi, Sho Onodera, Noboru Mesaki
    • Organizer
      16th Annual Meeting of the European College of Sport Science
    • Place of Presentation
      Liverpool, UK
    • Related Report
      2011 Research-status Report
  • [Presentation] Genome-wide association study of habitual exercise-induced improvement of arterial stiffness in Japanese adults2011

    • Author(s)
      Motoyuki Iemitsu, Haruka Murakami, Kiyoshi Sanada, Yuko Gando, Ryoko Kawakami, Noriyuki Fuku, Koichiro Hayashi, Motohiko Miyachi
    • Organizer
      58th Annual Meeting and 2nd World Congress on Exercise is Medicine of the American College of Sports Medicine
    • Place of Presentation
      Denver, Colorado, USA
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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