| Project/Area Number |
23700919
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | University of Nagasaki |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
SURUGA Kazuhito 長崎県立大学, 看護栄養学部, 准教授 (70315852)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | ビタミン A / all-trans レチノイン酸 / 脂肪組織 / 高脂肪食 / 脂質代謝 / エネルギ / ー消費量 / レチノイン酸 / エネルギー消費 / 脂質燃焼 / ビタミンA / 肥満 |
|---|
| Research Abstract |
The high-fat diets (HFD)-fed mice increased in adipose tissue levels, compared with control diets (AIN-93) fed mice. The adipose tissue levels of HFD-fed mice were decreased by oral administration of all-trans retinoic acid (ATRA). Moreover, the orally administrated HFD-fed mice of ATRA increased in energy expenditures due to enhancement of fat combustion. T aken together, ATRA could protect from HFD-induced obesity .
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