| Project/Area Number |
23700941
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Matsuyama University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 柑橘類由来成分 / オーラプテン / ヘプタメトキシフラボン / 中枢神経系 / 脳虚血 / 抗炎症 / 脳由来神経栄養因子 / 柑橘類 / 河内晩柑 / 抗炎症作用 / 柑橘類果皮成分 |
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| Research Abstract |
Functional effect of citrus compounds, auraptene (AUR) and3,5,6,7,8,3’,4’-heptamethoxyflavone (HMF), on the central nervous system were investigated using with the global ischemia, LPS-induced inflammation and MK-801-induced dementia models. AUR and HMF showed anti-inflammatory effect and enhancing effect of BDNF production in the brain hippocampus.
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