| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Research Abstract |
We performed mass spectrometry-based quantitative phosphoproteomic analysis to search for biomarker candidates by using surgically extracted colorectal cancer tissues. Novel biomarker candidates were identified by optimization of analysis conditions. For the selection of candidate genes, pathway analysis and comparison with the results of metastatic cancer cell lines were performed. Also by in vitro invasion assay, we have identified a novel functional molecule involved in cancer invasion.
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