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Preparation of novel polymer gel dosimeters based on a radiation-crosslinked gel

Research Project

Project/Area Number 23710073
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Risk sciences of radiation/Chemicals
Research InstitutionJapan Atomic Energy Agency

Principal Investigator

HIROKI Akihiro  独立行政法人日本原子力研究開発機構, 原子力科学研究部門・量子ビーム応用研究センター, 研究副主幹 (10370462)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords多糖類ゲル / ヒドロキシプロピルセルロース / 放射線橋かけ技術 / 電子線 / γ線 / ポリマーゲル線量計 / 白濁度合い / 吸光度
Research Abstract

Polymer gel dosimeters based on radiation-crosslinked hydroxypropyl cellulose (HPC) gel were prepared, which comprised 2-hydroxyethyl methacrylate (HEMA) and polyethylene glycol dimethacrylate (9G) as less toxic monomers and tetrakis (hydroxylmethyl) phosphonium chloride (THPC) as an antioxidant. The polymer gel dosimeters showed cloudiness at only 1 Gy by exposing to 60Co -ray, in which the cloudiness increased approximately linearly with the dose up to 10 Gy. At the same dose, the increase in the cloudiness appeared with increasing concentration of 9G. It was found that the dose response depended on the composition ratio between HEMA, 9G and THPC.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (19 results)

All 2014 2013 2012 Other

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (15 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Radiation-induced Change of Optical Property of Hydroxypropyl Cellulose Hydrogel Containing Methacrylate Compounds: As a Basis for Development of a New Type of Radiation Dosimeter2014

    • Author(s)
      S. Yamashita, A. Hiroki, and M. Taguchi
    • Journal Title

      Radiation Physics and Chemistry

      Volume: 101 Pages: 53-58

    • DOI

      10.1016/j.radphyschem.2014.04.004

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 放射線橋かけ技術を用いたゲルの創生研究とゲル線量計への展開2013

    • Author(s)
      廣木章博
    • Journal Title

      放射線と産業

      Volume: 135 Pages: 15-18

    • URL

      http://www.rada.or.jp/radi&indu/hsmaga.html

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Journal Article] (2) New Polymer Gel Dosimeters Consisting of Less Toxic Monomers with Radiation-crosslinked Gel Matrix2013

    • Author(s)
      A. Hiroki, S. Yamashita, Y. Sato, N. Nagasawa, and M. Taguchi
    • Journal Title

      J. Phys.: Conf. Ser.

      Volume: 444 Pages: 12028-12028

    • DOI

      10.1088/1742-6596/444/1/012028

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Presentation] 環境にやさしいポリマーゲル線量計の開発2013

    • Author(s)
      廣木章博
    • Organizer
      第8回高崎量子応用シンポジウム
    • Place of Presentation
      高崎シティーギャラリー(高崎)
    • Related Report
      2013 Final Research Report
  • [Presentation] ヒドロキシプロピルセルロースを母材とするポリマーゲル線量計の開発~重粒子線治療での利用を目指して~2013

    • Author(s)
      廣木章博
    • Organizer
      第56回日本放射線化学討論会
    • Place of Presentation
      広島大学(東広島)
    • Related Report
      2013 Final Research Report
  • [Presentation] 新規ポリマーゲル線量計の放射線感受性2013

    • Author(s)
      廣木章博
    • Organizer
      第106回日本医学物理学術大会
    • Place of Presentation
      大阪大学(吹田)
    • Related Report
      2013 Final Research Report
  • [Presentation] 新規ポリマーゲル線量計の放射線感受性2013

    • Author(s)
      廣木章博、山下真一、大城佳子、盛武敬、田口光正
    • Organizer
      第106回 日本医学物理学会学術大会
    • Place of Presentation
      大阪大学コンベンションセンター(吹田市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ヒドロキシプロピルセルロースを母材とするポリマーゲル線量計の開発 ~重粒子線治療での利用を目指して~2013

    • Author(s)
      廣木章博、山下真一、田口光正、村上健
    • Organizer
      第56回日本放射線化学討論会
    • Place of Presentation
      広島大学学士会館東広島キャンパス(東広島市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 環境にやさしいポリマーゲル線量計の開発2013

    • Author(s)
      廣木章博、山下真一、木村敦、長澤尚胤、田口光正
    • Organizer
      第8回高崎量子応用シンポジウム
    • Place of Presentation
      高崎シティーギャラリー(高崎)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 放射線橋かけ多糖類ゲルと低毒性モノマーから成るポリマーゲル線量計の作製2013

    • Author(s)
      廣木章博、山下真一、木村敦、長澤尚胤、田口光正
    • Organizer
      日本化学会群馬地区地域懇談会
    • Place of Presentation
      高崎量子応用研究所(高崎)
    • Related Report
      2013 Annual Research Report
  • [Presentation] New polymer gel dosimeters consisting of less toxic monomers with radiation-crosslinked gel matrix2013

    • Author(s)
      A. Hiroki, S. Yamashita, Y. Sato, N. Nagasawa, M. Taguchi
    • Organizer
      7th International Conference on 3D Radiation Dosimetry
    • Place of Presentation
      Shangri-La Hotel (Sydney, オーストラリア)
    • Related Report
      2012 Research-status Report
  • [Presentation] Dose Response of Naturally-Occuring-Polymer-Based Gel Dosimeter: Composition Effects on White Turbidity Increase by Irradiations2013

    • Author(s)
      S. Yamashita, A. Hiroki, N. Nagasawa, T. Murakami, M. Taguchi
    • Organizer
      4th Asia Pacific Symposium on Radiation Chemistry
    • Place of Presentation
      Huangshan International Hotel (Huangshan, 中国)
    • Related Report
      2012 Research-status Report
  • [Presentation] 放射線橋かけ技術を用いて作製したポリマーゲル線量計~白濁化に及ぼすモノマーの種類と組成の影響~2012

    • Author(s)
      廣木章博
    • Organizer
      第1回3Dゲル線量計研究会
    • Place of Presentation
      広島大学(広島)
    • Year and Date
      2012-12-02
    • Related Report
      2013 Final Research Report
  • [Presentation] New polymer gel dosimeters consisting of less toxic monomers with radiation-crosslinked gel matrix2012

    • Author(s)
      A. Hiroki
    • Organizer
      7th International Conference on 3D Radiation Dosimetry
    • Place of Presentation
      Shangri-La Hotel (Sydney)
    • Related Report
      2013 Final Research Report
  • [Presentation] 多糖類を母材としたシート状ポリマーゲル線量計の開発~照射に伴う白濁化と線質効果~2012

    • Author(s)
      山下真一, 廣木章博, 長澤尚胤, 田口光正,村上健
    • Organizer
      第49回アイソトープ・放射線研究発表会
    • Place of Presentation
      東大弥生講堂(東京)
    • Related Report
      2012 Research-status Report
  • [Presentation] ヒドロキシプロピルセルロースを用いたポリマーゲル線量計の作製2012

    • Author(s)
      廣木章博, 山下真一,長澤尚胤, 田口光正
    • Organizer
      第55回 高崎量子応用シンポジウム
    • Place of Presentation
      高崎シティーギャラリー(高崎)
    • Related Report
      2012 Research-status Report
  • [Presentation] 放射線橋かけ技術を用いて作製したポリマーゲル線量計~白濁化に及ぼすモノマーの種類と組成の影響~2012

    • Author(s)
      廣木章博,山下真一, 田口光正
    • Organizer
      第1回3Dゲル線量計研究会
    • Place of Presentation
      広島大学病院会議室(広島)
    • Related Report
      2012 Research-status Report
  • [Presentation] ヒドロキシプロピルセルロースを母材とするゲル線量計の開発

    • Author(s)
      山下真一,廣木章博,長澤尚胤,田口光正
    • Organizer
      放射線化学会
    • Place of Presentation
      大阪大学 産業科学研究所
    • Related Report
      2011 Research-status Report
  • [Patent(Industrial Property Rights)] ポリマーゲル線量計2013

    • Inventor(s)
      山下真一、廣木章博、田口光正、水本佳子、盛武敬
    • Industrial Property Rights Holder
      独立行政法人日本原子力研究開発機構、国立大学法人筑波大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-061789
    • Filing Date
      2013-03-25
    • Related Report
      2013 Final Research Report 2012 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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