Bioaccumulation of Halogenated and Non-halogenated Flame Retardants through Marine Food Web

• Project/Area Number: 23710077
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Risk sciences of radiation/Chemicals
• Research Institution: Ehime University
• Principal Investigator: ISOBE Tomohiko 愛媛大学, 上級研究員センター, 講師 (50391066)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: 生物濃縮 / 臭素系難燃剤 / リン酸エステル系難燃剤 / 魚類生態系 / 代替難燃剤

Research Abstract

Since PBDEs were listed in Stockholm Convention, halogenated alternative flame retardants and phosphorus flame retardants (PFRs) are of public concern. Contamination status and biomagnification of those alternative flame retardants were investigated in the coastal waters of Asia. Results suggest that PBDEs have been substituted by halogenated alternatives in industrialized nations. In addition, levels of triphenyl phosphate (TPhP) in fish showed a positive correlation with δ15N, indicating that it was biomagnifiedthrough food web.

Research Products

• [Journal Article] Accumulation of brominated flame retardants and polychlorinated biphenyls in human breast milk and scalp hair from the Philippines: Levels, distribution and profiles (2013)
  • Author(s): Govindan Malarvannan
  • Journal Title: Science of the Total Environment Volume: 422 Pages: 366-379
  • DOI: 10.1016/j.scitotenv.2012.10.005
  • Peer Reviewed
• [Journal Article] Perchlorate Contamination of Groundwater from Fireworks Manufacturing Area in South India (2013)
  • Author(s): Tomohiko Isobe
  • Journal Title: Environmental Monitoring and Assessment Volume: - Issue: 7 Pages: 5627-5637
  • DOI: 10.1007/s10661-012-2972-7
  • Peer Reviewed
• [Journal Article] Organophosphorus flame retardants in house dust from the Philippines: Occurrence and assessment of human exposure (2013)
  • Author(s): Joon-Woo Kim
  • Journal Title: Environmental Science and Pollution Research Volume: 20 Issue: 2 Pages: 812-822
  • DOI: 10.1007/s11356-012-1237-x
  • Peer Reviewed
• [Journal Article] Contamination by perfluorinated compounds in water near waste recycling and disposal sites in Vietnam (2013)
  • Author(s): Joon-Woo Kim
  • Journal Title: Environmental Monitoring and Assessment Volume: 185 Issue: 4 Pages: 2909-2919
  • DOI: 10.1007/s10661-012-2759-x
  • Peer Reviewed
• [Journal Article] Geographical distribution of non-PBDE-brominated flame retardants in mussels from Asian coastal waters (2012)
  • Author(s): Isobe, T., Ogawa, S. P., Ramu, K., Sudaryanto, A. and Tanabe, S
  • Journal Title: Environmental Science & Pollution Research Volume: 19(8) Issue: 8 Pages: 3107-3117
  • DOI: 10.1007/s11356-012-0945-6
• [Journal Article] Assessment of human exposure to halogenated compounds and electronic waste recycling activities in Ghana (2012)
  • Author(s): Asante, K. A.
  • Journal Title: Organohalogen Compounds Volume: 74 Pages: 1170-1173
• [Journal Article] Transfer potency and accumulation features of halogenated phenolic compounds into the brain of finless porpoise (Neophocaena phocaenoides) (2012)
  • Author(s): Ochiai, M.
  • Journal Title: Organohalogen Compounds Volume: 74 Pages: 935-938
• [Journal Article] Spatial distribution and bioaccumulation of polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDs) and polychlorinated biphenyls (PCBs) in aquatic ecosystems of Seto Inland Sea, Japan (2012)
  • Author(s): Isobe, T.
  • Journal Title: Organohalogen Compounds Volume: 74 Pages: 485-488
• [Journal Article] Levels and distribution of organophosphorus flame retardants and plasticizers in fishes from Manila Bay, the Philippines (2011)
  • Author(s): Kim, J.W.
  • Journal Title: Environmental Pollution Volume: 159(12) Issue: 12 Pages: 3653-3659
  • DOI: 10.1016/j.envpol.2011.07.020
  • Peer Reviewed
• [Journal Article] Multiresidue analytical method for the determination of antimicrobials, preservatives, benzotriazole UV stabilizers, flame retardants and plasticizers in fish using ultra high performance liquid chromatography coupled with mass spectrometry (2011)
  • Author(s): Joon-Woo Kim
  • Journal Title: Journal of Chromatography A Volume: 1218 Issue: 22 Pages: 3511-3520
  • DOI: 10.1016/j.chroma.2011.04.006
  • Peer Reviewed
• [Journal Article] Contamination Status of POPs and BFRs and Relationship with Parasitic Infection in Finless Porpoises (Neophocaena phocaenoides) from Seto Inland Sea and Omura Bay, Japan (2011)
  • Author(s): Tomohiko Isobe
  • Journal Title: Environmental Pollution Volume: 63 Issue: 5-12 Pages: 564-571
  • DOI: 10.1016/j.marpolbul.2011.01.014
  • Peer Reviewed
• [Journal Article] Determination of preservative and antimicrobial compounds in fish from Manila Bay, Philippines using ultra high performance liquid chromatography tandem mass spectrometry, and assessment of human dietary exposure (2011)
  • Author(s): Ramaswamy, B.R.
  • Journal Title: Journal of Hazardous Materials Volume: 192(3) Issue: 3 Pages: 1739-1745
  • DOI: 10.1016/j.jhazmat.2011.07.006
  • Peer Reviewed
• [Journal Article] Contamination and bioaccumulation of benzotriazole ultraviolet stabilizers in fish from Manila Bay, the Philippines using an ultra-fast liquid chromatography-tandem mass spectrometry (2011)
  • Author(s): Kim, J.W.
  • Journal Title: Chemosphere Volume: 85(5) Issue: 5 Pages: 751-758
  • DOI: 10.1016/j.chemosphere.2011.06.054
  • Peer Reviewed
• [Journal Article] Characterization of polychlorinated biphenyls and brominated flame retardants in surface soils from Surabaya, Indonesia (2011)
  • Author(s): Ilyas, M.
  • Journal Title: Chemosphere Volume: 83(6) Issue: 6 Pages: 783-791
  • DOI: 10.1016/j.chemosphere.2011.02.067
  • Peer Reviewed
• [Journal Article] Levels and distribution of polybrominated diphenyl ethers and organochlorine compounds in sea turtles from Japan (2011)
  • Author(s): Govindan Malarvannan
  • Journal Title: Marine Pollution Bulletin Volume: 63 Issue: 5-12 Pages: 172-178
  • DOI: 10.1016/j.marpolbul.2011.02.010
  • Peer Reviewed
• [Journal Article] Contamination status and spatial distribution of organochlorine compounds in fishes from Nansei Islands, Japan (2011)
  • Author(s): Govindan Malarvannan
  • Journal Title: Environmental Pollution Volume: 63 Issue: 5-12 Pages: 541-547
  • DOI: 10.1016/j.marpolbul.2011.02.002
  • Peer Reviewed
• [Journal Article] Brominated flame retardants in food samples collected from the Philippines (2011)
  • Author(s): Malarvannan, G., Isobe, T., Covaci, A., Takahashi, S., Prudente, M. and Tanabe, S.
  • Journal Title: Organohalogen Compounds Volume: 73 Pages: 579-582
• [Journal Article] Assessment of human exposure to PCBs and BFRs through fish consumption in Ghana (2011)
  • Author(s): Asante, K. A., Takahashi, S., Itai, T., Isobe, T., Devanathan, G., Dapaah-Siakwan, S., Agyakwah, S. K., Tanabe S.
  • Journal Title: Organohalogen Compounds Volume: 73 Pages: 855-858
• [Journal Article] Organohalogen contaminants in dust samples from different indoor environments in India (2011)
  • Author(s): Devanathan, G., Subramanian, An., Isobe, T., Kajiwara, N., Suzuki, G., Asante, K. A., Takahashi, S. and Tanabe, S.
  • Journal Title: Organohalogen Compounds Volume: 73 Pages: 1011-1014
• [Journal Article] Polychlorinated biphenyls and polybrominated diphenyl ethers in human breast milk from mothers living in coastal area of Surabaya city, Indonesia (2011)
  • Author(s): Ilyas, M., Sudaryanto, A., Setiawan, I. E., Riyadi, A. S., Isobe, T.,Takahashi, S. and Tanabe, S.;
  • Journal Title: Organohalogen Compounds Volume: 73 Pages: 1551-1554
• [Journal Article] Accumulation of anthropogenic and natural origin organohalogen compounds in three porpoise species (2011)
  • Author(s): Ochiai, M., Nomiyama, K., Isobe, T., Yamada, T. K., Tajima, Y., Matsuishi, T., Amano, M. and Tanabe, S.
  • Journal Title: Organohalogen Compounds Volume: 73 Pages: 1709-1712
• [Journal Article] Contamination status of brominated flame retardants in harbor (Phocoena phocoena) and Dall’s (Phocoenoides dalli) porpoises from Hokkaido, Japan (2011)
  • Author(s): Isobe T., Saito, A., Matsuishi, T., Yamada, T. K., Tajima, Y., Tanabe, S.
  • Journal Title: Organohalogen Compounds Volume: 73 Pages: 1721-1724
• [Presentation] Spatial distribution and bioaccumulation of polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDs) and polychlorinated biphenyls (PCBs) in aquatic ecosystems of Seto Inland Sea, Japan (2012)
  • Author(s): Isobe, T., Hamada, H., Chang, K-H., Shibata, J-Y., Sogabe, A., Omori, K. and Tanabe, S
  • Organizer: 32nd International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2012)
  • Place of Presentation: Cairns, Australia
• [Presentation] 有機塩素化合物・臭素系難燃剤による東シナ海の魚介類汚染と生物濃縮 (2012)
  • Author(s): 磯部友彦・濱田宏基・張 光〓・宝来佐和子・高橋 真・田辺信介
  • Organizer: 第21回環境化学討論会
  • Place of Presentation: 松山市
• [Presentation] 茨城県鹿嶋市に集団座礁したカズハゴンドウ(Peponocephala electra)における有機ハロゲン化合物の汚染実態解明 (2012)
  • Author(s): 杉本里菜
  • Organizer: 日本セトロジー研究会第23回大会
  • Place of Presentation: 宮城県松島町
• [Presentation] ベトナムにおけるハウスダスト中有機リン系難燃剤の汚染実態 (2012)
  • Author(s): 金 俊佑
  • Organizer: 第21回環境化学討論会
  • Place of Presentation: 松山市
• [Presentation] ベトナム人母乳中の有機リン系難燃剤汚染 (2012)
  • Author(s): 武藤 衛
  • Organizer: 第21回環境化学討論会
  • Place of Presentation: 松山市
• [Presentation] Contamination by organophosphorus flame retardants (PFRs) in human breast milk from the Philippines (2012)
  • Author(s): Muto, M.
  • Organizer: SETAC (Society of Environmental Toxicology and Chemistry) Asia/Pacific 2012
  • Place of Presentation: 熊本市
• [Presentation] Benzotriazole ultraviolet stabilizers in house dust from e-waste recycling and rural areas in Vietnam: Levels, profiles and human exposure (2012)
  • Author(s): Kim, J. W.
  • Organizer: SETAC (Society of Environmental Toxicology and Chemistry) Asia/Pacific 2012
  • Place of Presentation: 熊本市
• [Presentation] Phosphorus flame retardants in house dust from e-waste recycling and rural areas in Vietnam (2012)
  • Author(s): Kim, J.W.
  • Organizer: Society of Environmental Toxicology and Chemistry (SETAC) North America 33rd Annual Meeting
  • Place of Presentation: Long Beach, USA
• [Presentation] Geographical distribution of non-PBDE type brominated flame retardants in mussels from Asian coastal waters. (2011)
  • Author(s): Isobe, T., Ogawa, S. P., Ramu, K. and Tanabe, S.
  • Organizer: 13th EuCheMS International Conference on Chemistry and the Environment
  • Place of Presentation: ETH Zurich, Switzerland
• [Presentation] 臭素系難燃剤の生物濃縮とヒトのリスク評価 (2011)
  • Author(s): 磯部 友彦・濱田 宏基・豊島 沙織・田辺 信介・張 光〓
  • Organizer: 第14回日本水環境学会シンポジウム
  • Place of Presentation: 仙台
• [Presentation] Determination of perfluoroalkyl compounds in aqueous samples from Vietnam. (2011)
  • Author(s): Isobe, T., Kim, J. W., Tue, N. M., Misaki, K., Takahashi, S., Viet, P. H. and Tanabe, S.
  • Organizer: The 6th Global COE International Symposium on Advanced Studies by Young Scientists on Environmental Pollution and Ecotoxicology
  • Place of Presentation: 松山市
• [Presentation] Contamination status of brominated flame retardants in harbor (Phocoena phocoena) and Dall’s (Phocoenoides dalli) porpoises from Hokkaido, Japan. (2011)
  • Author(s): Isobe, T., Saito, A., Matsuishi, T., Yamada, T. K., Tajima, Y., Tanabe, S.
  • Organizer: 31st International Symposium on Halogenated Persistent Organic Pollutants (DIOXIN 2011)
  • Place of Presentation: ブリュッセル（ベルギー）
• [Presentation] Geographical distribution of non-PBDE type brominated flame retardants in mussels from Asian coastal waters. (2011)
  • Author(s): Isobe, T., Ogawa, S. P., Ramu, K. and Tanabe, S.
  • Organizer: 13th EuCheMS International Conference on Chemistry and the Environment
  • Place of Presentation: チューリッヒ（スイス）
• [Presentation] Contamination status and accumulation features of brominated flame retardants in raptors from Japan. (2011)
  • Author(s): Isobe, T., Hashikawa, R., Hirata, S. H., Nomiyama, K., Mizukawa, H., Hayashi, T. and Tanabe, S.
  • Organizer: Society of Environmental Toxicology and Chemistry (SETAC) North America 32nd Annual Meeting
  • Place of Presentation: ボストン（アメリカ）
• [Presentation] 北海道沿岸に漂着・混獲した小型鯨類の化学汚染研究：ネズミイルカ(Phocoena phocoena)とイシイルカ(Phocoenoides dalli)の有機ハロゲン化合物汚染の実態解明 (2011)
  • Author(s): 磯部友彦・斎藤亜実・松石 隆・北村志乃・松田純佳・小林万里・田島木綿子・山田 格・田辺信介
  • Organizer: 日本セトロジー研究会第22回（名古屋）大会
  • Place of Presentation: 名古屋市
• [Presentation] 北海道沿岸のネズミイルカ（Phocoena phocoena）およびイシイルカ（Phocoenoides dalli）における有機ハロゲン化合物の汚染実態と経年変動 (2011)
  • Author(s): 磯部友彦・斎藤亜実・田口美緒子・北村志乃・松石 隆・田島木綿子・山田 格・田辺信介
  • Organizer: 第20回環境化学討論会
  • Place of Presentation: 熊本市
• [Presentation] 非PBDE臭素化代替難燃剤のアジア地域における汚染モニタリング (2011)
  • Author(s): 磯部友彦・小川翔平・Ramu, K.・田辺信介
  • Organizer: 第20回環境化学討論会
  • Place of Presentation: 熊本市
• [Presentation] 生物環境試料バンク（es-BANK）を活用した臭素系難燃剤による鯨類汚染の過去復元 (2011)
  • Author(s): 磯部友彦・斎藤亜実・忍穂井智子・Ramu, K.・松石 隆・田島木綿子・山田 格・天野雅男・田辺信介
  • Organizer: 第17回日本野生動物医学会大会
  • Place of Presentation: 府中市
• [Presentation] 臭素系難燃剤の生物濃縮とヒトのリスク評価 (2011)
  • Author(s): 磯部 友彦・濱田 宏基・豊島 沙織・田辺 信介・張 光玄
  • Organizer: 第14回日本水環境学会シンポジウム
  • Place of Presentation: 仙台市
• [Book] Interdisciplinary Studies on Environmental Chemistry, Vol. 6, Advanced Environmental Studies by Young Scientist (2012)
  • Author(s): Hamada, H., Isobe, T., Chang, K. H., Shibata, J., Omori, K. and Tanabe, S.
  • Publisher: TERRAPUB
• [Book] Contamination status and geographical distribution of polybrominated diphenyl ethers, hexabromocyclododecanes and polychlorinated biphenyls in fish from the Seto Inland Sea (2012)
  • Author(s): Hamada, H.
  • Total Pages: 470
  • Publisher: TERRAPUB
• [Book] Present status of contamination by polychlorinated biphenyls, polybrominated diphenyl ethers and hexabromocyclododecanes in India (2012)
  • Author(s): Devanathan, G.
  • Total Pages: 470
  • Publisher: TERRAPUB
• [Book] Contamination of brominated flame retardants (BFRs) in human hair from e-waste recycling site in Vietnam (2012)
  • Author(s): Muto, M.
  • Total Pages: 470
  • Publisher: TERRAPUB
• [Book] In Proceedings of Interdisciplinary Studies on Environmental Chemistry Vol. 5- Modeling and Analysis of Marine Envrionmental Problems (2011)
  • Author(s): Shohei P. Ogawa, Tomohiko Isobe, Karri Ramu, Annamalai Subramanian, Shinsuke Tanabe
  • Publisher: TERRAPUB
• [Book] Contamination by Brominated Flame Retardants (BFRs) in Common Cormorants from Lake Biwa. In Proceedings of Interdisciplinary Studies on Environmental Chemistry Vol. 5 Modeling and Analysis of Marine Envrionmental Problems (2011)
  • Author(s): Ryosuke Hashikawa, Tomohiko Isobe, Shin-ichi Yano, Tatsuya Kunisue, Kei Nakayama, Akiko Sudo, Shin Takahashi, Shinsuke Tanabe
  • Total Pages: 277
  • Publisher: TERRAPUB
• [Book] Accumulation of Brominated Flame Retardants in Harbour and Dall’s Porpoises from Hokkaido. In Proceedings of Interdisciplinary Studies on Environmental Chemistry Vol. 5 Modeling and Analysis of Marine Envrionmental Problems (2011)
  • Author(s): Ami Saito, Tomohiko Isobe, Takashi Matsuishi, Tadasu K. Yamada, Yuko Tajima, Shinsuke Tanabe
  • Total Pages: 277
  • Publisher: TERRAPUB
• [Book] Inter-species Differences of Hydroxylated Polychlorinated Biphenyls (OH-PCBs) in the Blood of Samll Cetaceans. In Proceedings of Interdisciplinary Studies on Environmental Chemistry Vol. 5 Modeling and Analysis of Marine Envrionmental Problems (2011)
  • Author(s): Mari Ochiai, Kei Nomiyama, Tomohiko Isobe, Takashi Matsuishi, Tadasu K. Yamada, Shinsuke Tanabe
  • Total Pages: 277
  • Publisher: TERRAPUB
• [Book] Monitoring of Contamination of Non-PBDE Brominated Flame Retardants in Asian Coastal Waters Using Mussels as a Bioindicator. In Proceedings of Interdisciplinary Studies on Environmental Chemistry Vol. 5 Modeling and Analysis of Marine Envrionmental Problems (2011)
  • Author(s): Shohei P. Ogawa, Tomohiko Isobe, Karri Ramu, Annamalai Subramanian, Shinsuke Tanabe
  • Total Pages: 277
  • Publisher: TERRAPUB