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Development of a micro fluidic device for simultaneous measurements of membrane dynamics and reaction of giant liposome

Research Project

Project/Area Number 23710150
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Microdevices/Nanodevices
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

NAKANE Yuko  独立行政法人理化学研究所, ナノバイオプローブ研究チーム, 特別研究員 (00546244)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywordsマイクロデバイス / 電気化学測定 / 同時測定 / メンブレノーム / 蛍光顕微鏡 / 電気化学 / 膜界面反応 / 膜界面 / 蛍光
Research Abstract

A micro fluidic device for simultaneous measurements of membrane dynamics and reaction of giant liposomes was developed. We designed a micro device for simultaneous measurement by both microscopy and electrochemistry and fabricated micro electrode on glass substrates. The fabricated micro electrode showed that it is available for electrochemical measurements. Hemin-modified giant liposomes were prepared as a model of catalytic biomembrane.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (14 results)

All 2013 2012 2011 Other

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (3 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Multilayered, Core/shell Nanoprobes Based on Magnetic Ferric Oxide Particles and Quantum Dots for Multimodality Imaging of Breast Cancer Tumors2012

    • Author(s)
      Qiang Ma, Yuko Nakane, Yuki Mori, Miyuki Hasegawa, Yoshichika Yoshioka, Yomonobu M. Watanabe, Kohsuke Gonda, Noriaki Ohuchi and Takashi Jin
    • Journal Title

      Biomaterials

      Pages: 8486-8494

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bovine serum albumin-coated quantum dots as a cytoplasmic viscosity probe in a single living cell2012

    • Author(s)
      Yuko Nakane, Akira Sasaki, Masataka Kinjo and akashi Jin
    • Journal Title

      Analytical methods

      Pages: 1903-1905

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sensing system for bisphenol A utilizing a molecularly imprinted polymer modified electrode2012

    • Author(s)
      Izumi Kubo, Nobuyuki Yokota and Yuko Nakane
    • Journal Title

      Advanced Materials Research

      Pages: 922-926

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characteristics of molecularly imprinted polymer thin layer for bisphenol A and response of the MIP-modified sensor2012

    • Author(s)
      Izumi Kubo, Nobuyuki Yokota, Yusuke Fuchiwaki, and Yuko Nakane
    • Journal Title

      ISRN Materials Science

      Volume: Article ID 861643

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sensing System for Bisphenol A Utilizing A Molecularly Imprinted Polymer Modified Electrode2012

    • Author(s)
      I. Kubo, N. Yokota and Y. Nakane
    • Journal Title

      Advanced Materials Research

      Volume: Vol.452-453 Pages: 92-926

    • DOI

      10.4028/www.scientific.net/amr.452-453.922

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Characteristics of Molecularly Imprinted Polymer(MIP) Thin Layer for Bisphenol A and Response of the MIP-Modified Sensor2012

    • Author(s)
      Izumi Kubo、Nobuyuki Yokota、Yusuke Fuchiwaki、Yuko Nakane
    • Journal Title

      ISRN Materials Science

      Volume: Vol.2012 Pages: 6-6

    • DOI

      10.5402/2012/861643

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] The establishment of bisphenol A (BPA) sensing system utilizing molecularly imprinted polymer receptor and electrochemical determination2011

    • Author(s)
      Izumi Kubo, Nobuyuki Yokota, Yuko Nakane and Yusuke Fuchiwaki
    • Journal Title

      International Journal of Electrochemistry

      Volume: Article ID 534936

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Saccharification of xylan by Thermobacillus composti and its immobilization on a hydrophilic porous gel carrier2011

    • Author(s)
      Yuko Nakane, Keiko Watanabe, Kanako Nakagawa and Toshifumi Sakaguchi
    • Journal Title

      Mokuzai Gakkaishi

      Pages: 143-149

    • NAID

      10029789763

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Presentation] アルブミン修飾量子ドットによる生きた細胞での細胞質粘性測定2012

    • Author(s)
      中根優子,佐々木章、金城政孝、神隆
    • Organizer
      第6回バイオ関連化学シンポジウム
    • Place of Presentation
      札幌
    • Related Report
      2012 Final Research Report
  • [Presentation] 量子ロッドを用いた蛍光相関分光法による細胞質粘度の定量的測定2011

    • Author(s)
      中根優子,佐々木章、金城政孝、神隆
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば
    • Related Report
      2012 Final Research Report
  • [Presentation] 量子ロッドを用いた蛍光相関分光法による細胞質粘性の定量的測定2011

    • Author(s)
      中根優子,佐々木章,金城政孝,神隆
    • Organizer
      第5回バイオ関連化学シンポジウム
    • Place of Presentation
      つくば国際会議場エポカルつくば
    • Related Report
      2011 Research-status Report
  • [Book] 薄膜の評価技術ハンドブック2013

    • Author(s)
      中根優子
    • Publisher
      テクノシステム
    • Related Report
      2012 Final Research Report
  • [Book] 薄膜の評価技術ハンドブック(第7章2節 疑似生体膜)2013

    • Author(s)
      中根優子(金原 粲 監修)
    • Total Pages
      620
    • Publisher
      株式会社テクノシステム
    • Related Report
      2012 Annual Research Report
  • [Remarks] 創価大学久保研究室

    • URL

      http://home.soka.ac.jp/~kubo/

    • Related Report
      2012 Annual Research Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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