Electrophysiological recording using Spatially Arranged Microelectrode Embedded into 3D Culture
| Project/Area Number |
23710151
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Microdevices/Nanodevices
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| Research Institution | Ritsumeikan University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 空間配列プローブ電極 / 3 次元培養 / マイクロバイオシステム / 3次元培養組織 / 包埋計測 |
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| Research Abstract |
3D cultures are more likely to mimic physiological tissue environments. This research focuses on spatialextracellular recordings inside 3D cultures using spatially arranged microelectrode embedded into 3Dcultures. Wire?bonding?based probe technology makes it possible to provide the 3D microelectrodes.We demonstrated electrophysiological activities inside 3D neuronal cultures could be successfullyrecorded using the embedded microelectrodes. We also indicated that cell manipulation, optical sensingand electrochemical sensing were integrated with the spatially arranged microelectrode.
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Report
(3 results)
Research Products
(14 results)
