DNA methylation analysis by surface plasmon resonance on a microhole array
Project/Area Number |
23710152
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Microdevices/Nanodevices
|
Research Institution | National Institute of Advanced Industrial Science and Technology |
Principal Investigator |
KURITA Ryoji 独立行政法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 (50415676)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | DNA / メチルシトシン / エピジェネティクス |
Research Abstract |
We report the sequence-selective discrimination of the cytosine methylation status in DNA with anti methylcytosine antibody for the first time. This was realized by employing an affinity measurement involving the target methylcytosine in a bulge region an
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Report
(4 results)
Research Products
(22 results)