| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
We have developed a cost-effective and time-efficient program DROMPA for ChIP-seq analysis. DROMPA can visualize a protein-binding map, which can reduce the total cost for an analysis. By using DROMPA, we comprehensively investigated the cohesin binding sites for human B-cells. We found that a part of cohesin sites colocalize with an enhancer marker with tissue-specific manner, and such sites were lost for CdLS, that is caused by the loss of cohesin function.
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