Development of novel cavity-shaped dialkylphosphine ligands andtheir application to catalytic reactions
| Project/Area Number |
23750036
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Organic chemistry
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
SASE Shohei 東京工業大学, 大学院・理工学研究科, 助教 (90515165)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 有機元素化学 / ホスフィン配位子 / 分子キャビティ / パラジウム / ホスフィン / 配位子 / 遷移金属錯体 / 触媒反応 |
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| Research Abstract |
Novel cavity-shaped dialkylarylphosphines that would achieve unprecedented “peripheral steric effect” on the coordinated metal have been developed. Four cavity-shaped phosphines with different cavity sizes have been synthesized, and their properties largely differ from the steric environment around the phosphorus atom. The cavity-shaped phosphines have been applied to Pd-catalyzed Suzuki-Miyaura coupling reaction, and it was found that the phosphines with a smaller cavity exert a higher catalytic activity than the larger ones. Investigations of auxiliary ligands revealed that pyridine derivatives enhance the catalytic activity.
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Report
(3 results)
Research Products
(40 results)
