Design and Synthesis of Octahedral Metal Complexes with Linear Multidentate Ligands
Project/Area Number |
23750108
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Synthetic chemistry
|
Research Institution | Nagoya University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 触媒設計 / 反応 / 鎖状多座配位子 / オクタへドラル錯体 / ルテニウム / 触媒反応 / 不斉水素化 / 機構解明 / オクタへドラル / 金属錯体 / Ph-BINAN-H-Py |
Research Abstract |
Asymmetric catalysis converts a prochiral substrate into an enantiomericallyenriched chiral product. The enantioselectivity has generally been interpreted as a result of competing diastereomorphic catalytic cycles involving a single chiral catalyst. We have designed and synthesized Ph-BINAN-H-Py which is characterized by i) inside sp^N/outside sp^N, ii) donor-acceptor bifunctional ability, and iii) cis-alpha-selective formation of octahedral metal complexes. The utility of ligands has been demonstrated in asymmetric hydrogenation of aromatic ketones in combination with a Ru-π-allyl precursor. A series of detailed mechanistic studies should stimulate our ideas for development of asymmetric molecular catalysis.
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Report
(3 results)
Research Products
(34 results)