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Preparation and application of glycocapsules with tailored wall thicknesses

Research Project

Project/Area Number 23750119
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Polymer chemistry
Research InstitutionChiba University

Principal Investigator

KOHRI Michinari  千葉大学, 大学院・工学研究科, 助教 (80512376)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords高分子カプセル / 糖鎖高分子 / レクチン / 表面開始グラフト重合 / 高分子微粒子 / コア-シェル粒子 / 表面開始リビンググラフト重合 / レクチン認識能 / カプセル材料 / レクチン認識
Research Abstract

In this study, we have successfully demonstrated the preparation of polymer brush capsules that had tailored hollow core sizes and capsule wall thicknesses. In addition, we utilized surface-initiated living radical polymerization technique for surface modification of particles with glycopolymers, and effects of graft shell thickness and compositions on lectin recognition of glycoparticles were investigated.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (35 results)

All 2013 2012 2011 Other

All Journal Article (13 results) (of which Peer Reviewed: 11 results) Presentation (19 results) Remarks (3 results)

  • [Journal Article] ラテックス粒子の生化学的分野への応 用,桑折道済2013

    • Author(s)
      谷口竜王
    • Journal Title

      日本接着学会誌

      Volume: 49 Issue: 12 Pages: 164-170

    • DOI

      10.1016/j.eurpolymj.2011.09.016

    • Related Report
      2012 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of graft shell thickness and compositions on lectin recognition of glycoparticles2013

    • Author(s)
      M. Kohri, F. Abo, S. Miki, T. Fujii, M. Kasuya, and T. Taniguchi
    • Journal Title

      J. Colloid Sci. Biotechnol.

      Volume: 2 Issue: 1 Pages: 45-52

    • DOI

      10.1166/jcsb.2013.1028

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Journal Article] Enzymatic emulsifier-free emulsion polymerization to prepare polystyrene particles using horseradish peroxidase as a catalyst2013

    • Author(s)
      M. Kohri
    • Journal Title

      Polym. J.

      Volume: 45 Issue: 3 Pages: 354-358

    • DOI

      10.1038/pj.2012.129

    • NAID

      10031155045

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of titania hollow particles with independently controlled void size and shell thickness by catalytic templating core–shell polymer particles2013

    • Author(s)
      T. Taniguchi
    • Journal Title

      Colloid Polym. Sci.

      Volume: 291 Issue: 1 Pages: 215-222

    • DOI

      10.1007/s00396-012-2658-2

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A colorless functional polydopamine thin layer as a basis for polymer capsules, Polymer.2012

    • Author(s)
      M. Kohri, H. Kohma, Y. Shinoda, M. Yamauchi, S. Yagai, T. Kojima, T. Taniguchi, and K. Kishikawa
    • Journal Title

      Chemistry.

      Volume: 4 Issue: 9 Pages: 2696-2702

    • DOI

      10.1039/c3py00181d

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Enzymatic miniemulsion polymerization of styrene with a polymerizable surfactant2012

    • Author(s)
      M. Kohri
    • Journal Title

      Polym. Chem.

      Volume: 3 Issue: 4 Pages: 900-906

    • DOI

      10.1039/c2py00542e

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Surface-initiated enzymatic vinyl polymerization: synthesis of polymer-grafted silica particles using horseradish peroxidase as catalyst2012

    • Author(s)
      H. Fukushima
    • Journal Title

      Polym. Chem.

      Volume: 3 Issue: 5 Pages: 1123-1125

    • DOI

      10.1039/c2py20036h

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of surfactant type on enzymatic miniemulsion polymerization using horseradish peroxidase as a catalyst2012

    • Author(s)
      M. Kohri
    • Journal Title

      Chem. Lett.

      Volume: 41 Issue: 10 Pages: 1131-1133

    • DOI

      10.1246/cl.2012.1131

    • NAID

      130004426335

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Small-angle neutron scattering study on specific polymerization loci induced by a copolymerization of polymerizable surfactant and styrene in miniemulsion polymerization2012

    • Author(s)
      R. Motokawa
    • Journal Title

      Macromolecules

      Volume: 45 Issue: 23 Pages: 9435-9444

    • DOI

      10.1021/ma301776b

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation of organic/inorganic hybrid and hollow particles by catalytic deposition of silica onto core/shell heterocoagulates modified with poly[2-(N,N-dimethylamino)ethyl methacrylate]2012

    • Author(s)
      T. Taniguchi
    • Journal Title

      J. Colloid Interface Sci.

      Volume: 368 Issue: 1 Pages: 107-114

    • DOI

      10.1016/j.jcis.2011.11.077

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preparation and lectin binding specificity of polystyrene particles grafted with glycopolymers bearing S-linkedcarbohydrates2011

    • Author(s)
      M.Kohri,M.Sato, F. Abo, T. Inada, M. Kasuya, T. Taniguchi, and T. Nakahira
    • Journal Title

      Eur. Polym. J.

      Volume: 47 Pages: 2351-2360

    • Related Report
      2012 Final Research Report
  • [Journal Article] Photochemical conversion of the o-nitrobenzyl-C-glucoside to a sugar lactone2011

    • Author(s)
      M. Kohri, T. Kimura, Y. Shinoda, T. Taniguchi, and T. Nakahira
    • Journal Title

      Carbohydr. Res.

      Volume: 346 Issue: 18 Pages: 2965-2969

    • DOI

      10.1016/j.carres.2011.10.027

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Preparation of polymer core-shell particles supporting gold nanoparticles2011

    • Author(s)
      T. Taniguchi, T. Inada, T. Kashiwakura, F. Murakami, M. Kohri, and T. Nakahira
    • Journal Title

      Colloids Surf. A: Physicochem. Eng. Aspects

      Volume: 377 Issue: 1-3 Pages: 63-69

    • DOI

      10.1016/j.colsurfa.2010.12.026

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] カラーレスなポリドーパミン薄膜を下地とする高分子ブラシカプセルの作製2013

    • Author(s)
      桑折道済・高麗寛人・篠田義弘・谷口竜王・岸川圭希
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      滋賀
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] ポリドーパミン層を下地として用いる高分子ブラシからなる自立薄膜の作製2013

    • Author(s)
      篠田義弘
    • Organizer
      第30回千葉地域活動若手セミナー
    • Place of Presentation
      千葉
    • Related Report
      2012 Annual Research Report
  • [Presentation] 酵素を触媒とする高分子微粒子の合成ならびに表面改質2013

    • Author(s)
      桑折道済
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      滋賀
    • Related Report
      2012 Annual Research Report
  • [Presentation] 酵素触媒ミニエマルション重合における界面活性剤の種類が与える影響2013

    • Author(s)
      小林綾華
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      滋賀
    • Related Report
      2012 Annual Research Report
  • [Presentation] 高分子薄膜を下地とする高分子ブラシからなるカプセル材料2012

    • Author(s)
      高麗寛人・桑折道済・谷口竜王・岸川圭希
    • Organizer
      第17回高分子ミクロスフェア討論会
    • Place of Presentation
      仙台
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] Enzymatic Miniemulsion Polymerization with a Cationic Polymerizable Surfactant using Horseradish Peroxidase as a Catalyst2012

    • Author(s)
      M. Kohri
    • Organizer
      Polymers in Dispersed Media 2012 (PDM2012)
    • Place of Presentation
      France(Lyon)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Preparation of polystyrene particles by enzymatic radical polymerization2012

    • Author(s)
      M. Kohri
    • Organizer
      International Association of Colloid and Interface Scientists, Conference (IACIS 2012)
    • Place of Presentation
      仙台
    • Related Report
      2012 Annual Research Report
  • [Presentation] シリカ粒子表面からの酵素触媒グラフト重合によるコア-シェル型粒子の作製2012

    • Author(s)
      桑折道済
    • Organizer
      第61回高分子学会年次大会
    • Place of Presentation
      横浜
    • Related Report
      2012 Annual Research Report
  • [Presentation] カチオン性サーフマーを用いた酵素触媒ミニエマルション重合による高分子微粒子の作製2012

    • Author(s)
      小林綾華
    • Organizer
      第2回CSJ化学フェスタ
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] 酵素触媒ソープフリー乳化重合による高分子微粒子の作製2012

    • Author(s)
      桑折道済
    • Organizer
      第17回高分子ミクロスフェア討論会
    • Place of Presentation
      仙台
    • Related Report
      2012 Annual Research Report
  • [Presentation] 表面開始イニファーター重合を用いた糖鎖高分子グラフト化高分子微粒子の調製とレクチン認識能の評価2011

    • Author(s)
      阿保芙美奈・三木翔・春谷昌克・桑折道済・谷口竜王・中平隆幸
    • Organizer
      第1回CSJ化学フェスタ
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report 2011 Research-status Report
  • [Presentation] 高分子微粒子表面でのイニファーター重合による糖鎖高分子シェル層の構築2011

    • Author(s)
      阿保芙美奈・三木翔・藤井誠子・桑折道済・谷口竜王・中平隆幸
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山
    • Related Report
      2012 Final Research Report 2011 Research-status Report
  • [Presentation] 酵素を触媒とする表面開始グラフト重合による高分子微粒子表面の改質2011

    • Author(s)
      桑折 道済・福島 悠佳・谷口 竜王・中平 隆幸
    • Organizer
      第60回高分子学会年次大会
    • Place of Presentation
      大阪
    • Related Report
      2011 Research-status Report
  • [Presentation] 酵素触媒ミニエマルション重合における開始剤の影響2011

    • Author(s)
      小林 綾華・桑折 道済・谷口 竜王・中平 隆幸
    • Organizer
      第60回高分子学会年次大会
    • Place of Presentation
      大阪
    • Related Report
      2011 Research-status Report
  • [Presentation] 酵素を触媒とする表面開始グラフト重合を用いたコア-シェル微粒子の作製2011

    • Author(s)
      福島 悠佳・桑折 道済・谷口 竜王・中平 隆幸
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山
    • Related Report
      2011 Research-status Report
  • [Presentation] 酵素触媒重合による機能性高分子微粒子の作製2011

    • Author(s)
      桑折 道済・小林 綾華・福島 悠佳・谷口 竜王・中平 隆幸
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山
    • Related Report
      2011 Research-status Report
  • [Presentation] 酵素触媒グラフト重合によるコア-シェル型有機/無機複合粒子の作製2011

    • Author(s)
      福島 悠佳・桑折 道済・谷口 竜王・中平 隆幸
    • Organizer
      第1回CSJ化学フェスタ
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Presentation] 酵素触媒ミニエマルション重合による高分子微粒子の作製における開始剤濃度の影響2011

    • Author(s)
      小林 綾華・ 福島 悠佳・ 桑折 道済・谷口 竜王・中平 隆幸
    • Organizer
      第1回CSJ化学フェスタ
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Presentation] 酵素触媒ラジカル重合による機能性高分子材料の作製2011

    • Author(s)
      桑折 道済・福島 悠佳・小林 綾華・高麗 寛人・谷口 竜王・中平 隆幸
    • Organizer
      第20回ポリマー材料フォーラム
    • Place of Presentation
      東京
    • Related Report
      2011 Research-status Report
  • [Remarks]

    • URL

      http://chem.tf.chiba-u.jp/gacb03/

    • Related Report
      2012 Final Research Report
  • [Remarks] 千葉大学 生体模倣高分子研究室

    • URL

      http://chem.tf.chiba-u.jp/gacb03/saito/toppu.html

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://chem.tf.chiba-u.jp/gacb03/saito/toppu.html

    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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