| Project/Area Number |
23760107
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Materials/Mechanics of materials
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| Research Institution | 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工学群) |
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Principal Investigator |
TSUKAMOTO Akira 防衛大学校(総合教育学群、人文社会科学群、応用科学群、電気情報学群及びシステム工, 応用科学群, 助教 (90511460)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 細胞バイオメカニクス |
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| Research Abstract |
Mechanical stresses induced on our body involve in multiple disorders. In this study, in order to understand how the mechanical stresses involve in those disorders, intracellular alterations of traction force were tried to be measured. For the measurement, measuring system was developed. Moreover, as a mechanism of the alterations, cytoskeletons were considered as a mechanical model. As a result, although alterations of intracellular traction forces remain indispensable noises for valid analysis, those of cellular traction forces were valid. In addition with alterations of cytoskeletons, it was indicated that ablation of cytoskeletons induced several types of alterations in cellular traction forces.
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