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Development of evaluation method for bacterial motility based on the flow dynamics and the large deviation mechanics

Research Project

Project/Area Number 23760161
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Fluid engineering
Research InstitutionOsaka University (2012-2013)
Kobe University (2011)

Principal Investigator

HANASAKI Itsuo  大阪大学, 基礎工学研究科, 助教 (10446734)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords応用力学 / ナノ・マイクロ流体 / 統計力学 / 力学系 / 揺らぎ / ブラウン運動 / 大偏差原理 / 時系列データ解析 / 機械工学 / 流体工学 / マイクロナノ流動現象 / 熱揺らぎ / 統計物理 / 微生物 / 大腸菌 / 大偏差 / 応用数理 / 流体力学
Research Abstract

Brownian motion is a fundamental phenomenon of nano/micro scale fluid dynamics. On the other hand, bacterial motility is known to show some stochasticity while essentially different from Brownian motion. Recently, there have been drastic developments in the techniques of single particle tracking (SPT) or single molecule tracking (SMT) due to the importance in the medical and biological applications as well as material processing. However, the analysis of the obtained trajectory data has not been addressed intensively compared to the measurement technology. In this study, we have developed the evaluation methodology based on the large deviation principle. In particular, we have shown that it is possible to elucidate the diffusion anisotropy of a prolate particle without the information of particle orientation. Furthermore, we have shown that the finite-sample effect can be useful in the characterization of bacterial motility.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (8 results)

All 2013 2012 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (6 results)

  • [Journal Article] Evaluation of Bacterial Motility from Non-Gaussianity of Finite-Sample Trajectories Using the Large Deviation Principle2013

    • Author(s)
      Itsuo HANASAKI and Satoyuki KAWANO
    • Journal Title

      Journal of Physics: Condensed Matter

      Volume: 25 Issue: 46 Pages: 465103-465103

    • DOI

      10.1088/0953-8984/25/46/465103

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Detection of diffusion anisotropy due to particle asymmetry from single-particle tracking of Brownian motion by the large-deviation principle2012

    • Author(s)
      Itsuo Hanasaki and Yoshitada Isono
    • Journal Title

      Physical Review E

      Volume: Vol.85 Issue: 5

    • DOI

      10.1103/physreve.85.051134

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 水溶液中の高分子の熱揺らぎに関する大偏差数値解析2013

    • Author(s)
      花崎逸雄,川野聡恭
    • Organizer
      日本機械学会第5回マイクロ・ナノ工学シンポジウム講演論文集
    • Place of Presentation
      仙台(pp.149-150)
    • Year and Date
      2013-11-06
    • Related Report
      2013 Final Research Report
  • [Presentation] 大偏差原理に基づく微生物の自発的運動の検出2013

    • Author(s)
      花崎逸雄,川野聡恭
    • Organizer
      日本機械学会2013年度年次大会
    • Place of Presentation
      岡山(No.13-1)
    • Year and Date
      2013-09-09
    • Related Report
      2013 Final Research Report
  • [Presentation] 大偏差原理に基づく微生物の自発的運動の検出2013

    • Author(s)
      花崎逸雄,川野聡恭
    • Organizer
      日本機械学会2013年度年次大会
    • Place of Presentation
      岡山
    • Related Report
      2013 Annual Research Report
  • [Presentation] 水溶液中の高分子の熱揺らぎに関する大偏差数値解析2013

    • Author(s)
      花崎逸雄,川野聡恭
    • Organizer
      日本機械学会第5回マイクロ・ナノ工学シンポジウム
    • Place of Presentation
      仙台
    • Related Report
      2013 Annual Research Report
  • [Presentation] 大偏差統計理論に基づく楕円体粒子のブラウン運動異方性の評価2012

    • Author(s)
      花崎逸雄,磯野吉正
    • Organizer
      日本機械学会第90期流体工学部門講演会講演論文集
    • Place of Presentation
      京都
    • Year and Date
      2012-11-18
    • Related Report
      2013 Final Research Report
  • [Presentation] 大偏差統計理論に基づく楕円体粒子のブラウン運動異方性の評価

    • Author(s)
      花崎逸雄
    • Organizer
      日本機械学会第90期流体工学部門講演会
    • Place of Presentation
      京都
    • Related Report
      2012 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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