Nonlinear Spatio-Temporal Dynamics of Electroporation: Modeling, Analysis, and Control
| Project/Area Number |
23760390
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Control engineering
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | エレクトロポレーション / 非線形動力学 / 制御技術 / 制御工学 / バイオテクノロジー / 電気機器工学 / マイクロマシン / 流体工学 |
|---|
| Research Abstract |
The goal of this research was to establish a control technology of electroporation in a single cell. Towards the goal, I analyzed nonlinear spatio-temporal dynamics emerging in electroporation of a single cell and synthesized a control protocol for regulating the electroporation. A new control protocol using amplitude-modulated electric fields for regulating the cell membrane permittivity was developed and demonstrated in numerical simulations.
|
Report
(3 results)
Research Products
(4 results)
