| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Research Abstract |
In recent years, N-nitrosodimethylamine (NDMA) which are potent mutagenic and carcinogenic compound in humans has been obtained as the byproducts of chlorine disinfection in drinking water supplies. Therefore, a sensitive and simple method for monitoring NDMA in tap water is urgently required. Recently, I developed a novel ultra-sensitive determination method for nitrosamines. This method is based on online UV irradiation after high-performance liquid chromatographic separation and subsequent luminol chemiluminescence detection.
In this study, I proposed a simple preparation procedure for measurement of NDMA in tap water. Furthermore, the developed method was used to monitor NDMA concentration in tap water. As the result, the seasonal change of concentration of NDMA in tap water was confirmed.
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