Preparation of bioresorbable bone-repairing materials which promote bone regeneration
Project/Area Number |
23760630
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Inorganic materials/Physical properties
|
Research Institution | Tohoku University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 機能性セラミックス / 骨修復 / 骨再生 / リン酸カルシウム |
Research Abstract |
We aimed the preparation of bioresorbable bone-repairing materials which promote bone regeneration. We prepared silicate-containing tricalcium phosphate (TCP) and revealed that the sintered silicate-containing TCP showed higher apatite-forming ability in a simulated body fluid than the silicate-free TCP. When the compact of silicate-containingTCP powder was hydrothermally treated, the Ca-deficient HA ceramic composed of rod-shaped particles was obtained. On the other hand, we revealed that the dissolution rate of the Ca-deficient in the acidic buffer solution increased with the Ca-deficiency degree. We established the synthesis process and evaluated the basic materials.
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Report
(3 results)
Research Products
(14 results)