Direct measurements of degrees of multiple ionization of biomolecules induced by energetic heavy ions

• Project/Area Number: 23760826
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Nuclear engineering
• Research Institution: Kyoto University
• Principal Investigator: MAJIMA Takuya 京都大学, 大学院・工学研究科, 助教 (50515038)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2011: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
• Keywords: 高速イオン衝突 / 同時測定 / 多重電離 / 分子解離 / 多重分解 / 放射線物理 / 多重同時測定

Research Abstract

A multiple coincidence measurement system for collision experiments between fast ions and isolated biomolecules has been developed to elucidate physical processes in the first stage of radiation effects in biological systems. The number of emitted electrons has been measured to directly obtain degrees of multiple ionization of large molecules. Coincidence measurements between the number of electrons and product ions revealed fragmentation processesfrom transient highly excited ions with specific charge states. Furthermore, momentum vectors of fragment ions were obtained by applying the velocity map imaging technique.

Research Products

• [Journal Article] Spatial distribution of ions in a linear octopole radio-frequency ion trap in the space-charge limit (2012)
  • Author(s): T. Majima, G. Santambrogio, C. Bartels, A. Terasaki, T. Kondow, J. Meinen, and T. Leisner
  • Journal Title: Phys. Rev. A Volume: 85 Issue: 5
  • DOI: 10.1103/physreva.85.053414
  • Peer Reviewed
• [Journal Article] Collisioninduced Multiple Ionization of Polyatomic Molecules by Coincidence Measurements of Product Ions and the Number of Electrons (2012)
  • Author(s): T. Murai, T. Majima, Y. Adachi, M. Imai, H. Shibata, H. Tsuchida, and A. Itoh
  • Journal Title: Annual Report of Quantum Science and Engineering Center Volume: 14 Pages: 1-2
• [Journal Article] Measurement of The Number of Spectrum of Secondary Electrons by Using An Avalanche Photodiode Detector (2012)
  • Author(s): T. Nishio, T. Majima, T. Kishimoto, M. Imai, H. Shibata, H. Tsuchida, and A. Itoh
  • Journal Title: Annual Report of Quantum Science and Engineering Center Volume: 14 Pages: 3-5
• [Journal Article] Collision-induced Multiple Ionization of Polyatomic Molecules by Coincidence Measurements of Product Ions and the Number of Electrons (2012)
  • Author(s): T. Murai
  • Journal Title: Annual Report of Quantum Science and Engineering Center Volume: 14 Pages: 1-2
• [Journal Article] Measurement of The Number of Spectrum of Secondary Electrons by Using An Avalanche Photodiode Detector (2012)
  • Author(s): T. Nishio
  • Journal Title: Annual Report of Quantum Science and Engineering Cente Volume: 14 Pages: 3-5
• [Journal Article] Microhydration of the methylene blue cation in an electrospray ion source (2011)
  • Author(s): T. Sato, T. Majima, K. Hashimoto, K. Hashimoto, Y. Zama, J. Matsumoto, H. Shiromaru, K. Okuno, H. Tanuma, and T. Azuma
  • Journal Title: Eur. Phys. J Volume: D 63 Pages: 189-194
  • Peer Reviewed
• [Journal Article] C_60fragmentation in charge changing collisions of slow and high-Z Au+ions (2011)
  • Author(s): Y. Nakai, T. Majima, T. Mizuno, H. Tsuchida, and A. Itoh
  • Journal Title: Phys. Rev Volume: A 83 Issue: 5 Pages: 23201-23201
  • DOI: 10.1103/physreva.83.053201
  • Peer Reviewed
• [Journal Article] Multiple ionization and fragmentation of polyatomic molecules by fast heavy ions (2011)
  • Author(s): A. Itoh, T. Mizuno, and T. Majima
  • Journal Title: Phys.: Conf. Ser Volume: 288 Pages: 012027-012027
  • DOI: 10.1088/1742-6596/288/1/012027
  • Peer Reviewed
• [Journal Article] Coincidence measurements between fragment ions and the number of emitted electrons in heavy ion collisions with polyatomic molecules (2011)
  • Author(s): T. Murai, T. Majima, T. Kishimoto, H. Tsuchida, and A. Itoh
  • Journal Title: Annual Report of Quantum Science and Engineering Center Volume: 13 Pages: 1-3
• [Journal Article] Dissociation of CH_4 and C_2H_6induced by fast heavy ion collisions (2011)
  • Author(s): T. Kishimoto, T. Murai, T. Majima, H. Tsuchida, and A. Itoh
  • Journal Title: Annual Report of Quantum Science and Engineering Center Volume: 13 Pages: 4-6
• [Journal Article] Microhydration of the methylene blue cation in an electrospray ion source (2011)
  • Author(s): T.Sato, T.Majima, Kenro Hashimoto, Kohei Hashimoto, Y.Zama, J.Matsumoto, H.Shiromaru, K.Okuno, H.Tamura, T.Azuma
  • Journal Title: Euro.Phys.J.D Volume: 63 Issue: 2 Pages: 189-194
  • DOI: 10.1140/epjd/e2010-10526-y
  • Peer Reviewed
• [Journal Article] Dissociation of CH4 and C2H6 induced by fast heavy ion collisions (2011)
  • Author(s): T. Kishimoto, T. Murai, T. Majima, H. Tsuchida, and A. Itoh
  • Journal Title: Annual Report of Quantum Science and Engineering Center Volume: 13 Pages: 4-6
• [Presentation] 高速重イオンの荷電変換衝突における C_2H_6 分子の解離イオン速度分布イメージング (2013)
  • Author(s): 吉田慎太郎、安達泰之、間嶋拓也、今井誠、柴田裕実、土田秀次、伊藤秋男
  • Organizer: フォーラム21-イオンビームを用いた物理とその応用-
  • Place of Presentation: 京都府立大学,京都市
  • Year and Date: 2013-01-12
• [Presentation] 高速イオン-気相分子衝突における解離イオンの Velocity Map Imaging 測定 (2013)
  • Author(s): 吉田慎太郎,安達泰之,間嶋拓也,今井誠,土田秀次,柴田裕実,伊藤秋男
  • Organizer: 日本物理学会第68回年次大会
  • Place of Presentation: 広島大学,東広島市
• [Presentation] 高速重イオンの荷電変換衝突におけるC2H6分子の解離イオン速度分布イメージング (2013)
  • Author(s): 吉田慎太郎
  • Organizer: フォーラム２１-イオンビームを用いた物理とその応用-
  • Place of Presentation: 京都市
• [Presentation] 高速イオン－気相分子衝突における解離イオンのVelocity Map Imaging測定 (2013)
  • Author(s): 吉田慎太郎
  • Organizer: 日本物理学会第68回年次大会
  • Place of Presentation: 東広島市
• [Presentation] Correlation between multiple ionization and fragmentation of molecules in fast heavy ion collisions (2012)
  • Author(s): T. Majima
  • Organizer: Joint Symposium on Collision Processes of Highly-Charged Ions and Related Topics
  • Place of Presentation: Hachioji, Japan
  • Year and Date: 2012-02-03
• [Presentation] Direct Measurements of Multiple Ionization of Isolated Polyatomic Molecules Induced by Fast Ion Collisions (2012)
  • Author(s): T. Majima, Y. Adachi, S. O. Yoshida, T. Murai, T. Kishimoto, M. Imai, H. Shibata, H. Tsuchida and A. Itoh
  • Organizer: 8th International Symposium on Swift Heavy Ions in Matter
  • Place of Presentation: Kyoto, Japan
• [Presentation] Measurement of the number spectrum of secondary electrons by using an avalanche photodiode detector (2012)
  • Author(s): T. Nishio, T. Kishimoto, T. Majima, M. Imai, H. Shibata, H. Tsuchida, and A. Itoh
  • Organizer: 25th International Conference on Atomic Collisions in Solids
  • Place of Presentation: Kyoto, Japan
• [Presentation] 高速重イオン衝突による多原子分子からの生成イオン・放出電子個数の同時測定 (2012)
  • Author(s): 安達泰之,吉田慎太郎,間嶋拓也,今井誠,土田秀次,柴田裕実,伊藤秋男
  • Organizer: 原子衝突学会第37回年会
  • Place of Presentation: 電気通信大学,調布市
• [Presentation] アバランシェフォトダイオードによる二次電子個数分布の測定 (2012)
  • Author(s): 西尾達哉,岸本孝則,間嶋拓也,須田慎太郎,中野祐司,東俊行,今井誠,柴田裕美,土田秀次,伊藤秋男
  • Organizer: 日本物理学会 2012 年年次大会
  • Place of Presentation: 関西学院大学,西宮市
• [Presentation] 高速重イオン衝突によるエタン分子からの H_3^<+>生成機構 (2012)
  • Author(s): 村井太郎,安達泰之, 間嶋拓也,今井誠,土田秀次,柴田裕美,伊藤秋男
  • Organizer: 日本物理学会 2012 年年次大会
  • Place of Presentation: 関西学院大学,西宮市
• [Presentation] Direct Measurements of Multiple Ionization of Isolated Polyatomic Molecules Induced by Fast Ion Collisions (2012)
  • Author(s): T. Majima
  • Organizer: 8th International Symposium on Swift Heavy Ions in Matter
  • Place of Presentation: 京都市
• [Presentation] Measurement of the number spectrum of secondary electrons by using an avalanche photodiode detector (2012)
  • Author(s): T. Nishio
  • Organizer: 25th International Conference on Atomic Collisions in Solids
  • Place of Presentation: 京都市
• [Presentation] 高速重イオン衝突による多原子分子からの生成イオン･放出電子個数の同時測定 (2012)
  • Author(s): 安達泰之
  • Organizer: 原子衝突学会第37回年会
  • Place of Presentation: 調布市
• [Presentation] Correlation between multiple ionization and fragmentation of molecules in fast heavy ion collisions (2012)
  • Author(s): T. Majima
  • Organizer: Joint Symposium on Collision Processes of Highly-Charged Ions and Related Topics(招待講演)
  • Place of Presentation: 首都大学東京（東京都）
• [Presentation] アバランシェフォトダイオードによる二次電子個数分布の測定 (2012)
  • Author(s): 西尾達哉，岸本孝則，間嶋拓也，須田慎太郎，中野祐司，東俊行，今井誠，柴田裕美，土田秀次，伊藤秋男
  • Organizer: 日本物理学会2012年年次大会
  • Place of Presentation: 関西学院大学（兵庫県）
• [Presentation] 高速重イオン衝突によるエタン分子からのH3+生成機構 (2012)
  • Author(s): 村井太郎，安達泰之，間嶋拓也，今井誠，土田秀次，柴田裕美，伊藤秋男
  • Organizer: 日本物理学会2012年年次大会
  • Place of Presentation: 関西学院大学（兵庫県）
• [Presentation] はじめに（放射線が生体に与える影響－原子分子から生物まで－） (2012)
  • Author(s): 間嶋拓也
  • Organizer: 日本物理学会2012年年次大会
  • Place of Presentation: 関西学院大学（兵庫県）
• [Presentation] 気相分子からの解離イオン-放出電子個数の同時測定システムの開発 (2011)
  • Author(s): 間嶋拓也,村井太郎,岸本孝則,土田秀次,伊藤秋男
  • Organizer: 日本物理学会 2011 年秋季大会
  • Place of Presentation: 富山大学,富山市
• [Presentation] 放出電子個数測定によるフロン分子の特異な解離反応過程の解明 (2011)
  • Author(s): 村井太郎,岸本孝則,間嶋拓也,土田秀次,伊藤秋男
  • Organizer: 日本物理学会 2011 年秋季大会
  • Place of Presentation: 富山大学,富山市
• [Presentation] 高速重イオン衝突に伴うエタン分子からの解離イオン相関測定 (2011)
  • Author(s): 岸本孝則,村井太郎,間嶋拓也,土田秀次,伊藤秋男
  • Organizer: 日本物理学会 2011 年秋季大会
  • Place of Presentation: 富山大学,富山市
• [Presentation] Coincidence measurements between fragment ions and the number of emitted electrons in heavy ion collisions with polyatomic molecules (2011)
  • Author(s): T. Murai, T. Majima, T. Kishimoto, H. Tsuchida and A. Itoh
  • Organizer: 27th International Conference on Photonic, Electronic, and Atomic Collisions
  • Place of Presentation: Belfast, UK
• [Presentation] Coincidence measurements between fragment ions and the number of emitted electrons in heavy ion collisions with polyatomic molecules (2011)
  • Author(s): T. Murai, T. Majima, T. Kishimoto, H. Tsuchida and A. Itoh
  • Organizer: 27th International Conference on Photonic, Electronic, and Atomic Collisions
  • Place of Presentation: Queen’s University Belfast (Belfast, UK)
• [Presentation] 京都大学マイクロビーム加速器の現状と将来計画 (2011)
  • Author(s): 土田秀次, 内藤正裕，間嶋拓也，今井誠，柴田裕美，高木郁二，伊藤秋男
  • Organizer: 第24回タンデム加速器及びその周辺技術の研究会
  • Place of Presentation: 奈良女子大学（奈良県）
• [Presentation] 気相分子からの解離イオン－放出電子個数の同時測定システムの開発 (2011)
  • Author(s): 間嶋拓也，村井太郎，岸本孝則，土田秀次，伊藤秋男
  • Organizer: 日本物理学会2011年秋季大会
  • Place of Presentation: 富山大学（富山県）
• [Presentation] 放出電子個数測定によるフロン分子の特異な解離反応過程の解明 (2011)
  • Author(s): 村井太郎，岸本孝則，間嶋拓也，土田秀次，伊藤秋男
  • Organizer: 日本物理学会2011年秋季大会
  • Place of Presentation: 富山大学（富山県）
• [Presentation] 高速重イオン衝突に伴うエタン分子からの解離イオン相関測定 (2011)
  • Author(s): 岸本孝則，村井太郎，間嶋拓也，土田秀次，伊藤秋男
  • Organizer: 日本物理学会2011年秋季大会
  • Place of Presentation: 富山大学（富山県）
• [Remarks] ホームページ
  • URL: http://www.nucleng.kyoto-u.ac.jp/people/majima/