Investigations on Radiobiological effects induced by high dose rate irradiation with laser-accelerated protons.
Project/Area Number |
23760831
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Nuclear engineering
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Research Institution | Japan Atomic Energy Agency |
Principal Investigator |
YOGO Akifumi 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 研究副主幹 (50421441)
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Project Period (FY) |
2011 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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Keywords | 放射線工学 / ビーム科学 / レーザー駆動粒子線 / レーザーイオン加速 / 高強度レーザー / 放射線生物効果 / 高線量率照射 / レーザー物質相互作用 / レーザー粒子加速 |
Research Abstract |
Recently, high-intensity laser ion acceleration has been suggested as a potential, cost-saving alternative technology to conventional accelerators for radiotherapy. In this work, investigations of the biological effects of the high bunch current and short bunch duration, that are typical of laser-acceleration, are reported. The radiobiological effects of high dose-rate irradiation with laser-driven proton beams are compared with those of beams derived from conventional ion accelerators.
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Report
(3 results)
Research Products
(20 results)
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[Journal Article] Measurement of DNA Double-Strand Break Yield in Human Cancer Cells by High Current, Short Duration Bunches of Laser-Accelerated Protons2011
Author(s)
Akifumi Yogo, Katsutoshi Sato, Masaharu Nishikino, Takuya Maeda, Hironao Sakaki, Toshihiko Hori, Koichi Ogura, Mamiko Nishiuchi, Teruki Teshima, Hiroaki Nishimura, Kiminori Kondo, Paul R. Bolton, and Shunichi Kawanishi
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Journal Title
Jpn. J. Appl. Phys.
Volume: 50
Pages: 106401-106401
NAID
Related Report
Peer Reviewed
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