Analysis on tolerance of polyploid plants to DNA damage

Research Project

Project/Area Number	23770007
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Genetics/Genome dynamics
Research Institution	National Institute of Genetics
Principal Investigator	INAGAKI Soichi 国立遺伝学研究所, 総合遺伝研究系, 助教 (00597883)
Project Period (FY)	2011 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000) Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000) Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords	植物 / 倍数性 / ゲノム維持 / 遺伝 / DNA損傷 / シロイヌナズナ / 相同組換え
Research Abstract	We explored the molecular mechanisms of tolerance of polyploid plants to DNA damage using genetic analysis. We found that some genes that are involved in the homologous recombination are required for the tolerance. This result suggests that polyploid plants have a different mechanism of the DNA repair than diploid plants. In addition, we found that the polyploid of mutants for DNA repair genes frequently showed developmental abnormality, suggesting that the proper development of polyploid plants needs DNA repair pathway

Report

(3 results)