Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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Outline of Final Research Achievements |
To clarify the mechanisms of secondary cell wall (SCW) formation during xylem vessel differentiation, we have screened the chemicals which affect the SCW formation. As a result, we could identify a compound sulfamethizole (SMZ), which had a novel bioactivity to induce abnormal branching and bending in spiral protoxylem SCWs. SMZ induced aberrant branching and bending cortical microtubules specifically during vessel cell differentiation, meaning that SMZ is a novel inhibitor against SCW formation mechanism in protoxylem and that SMZ could be an novel tool to investigate it further.
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