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Evolutional study on neuroendocrine system for regulating reproduction in social insects

Research Project

Project/Area Number 23770078
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Animal physiology/Animal behavior
Research InstitutionTamagawa University (2013)
Kanazawa Institute of Technology (2011-2012)

Principal Investigator

SASAKI Ken  玉川大学, 農学部, 准教授 (40387353)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsドーパミン / ハナバチ類 / カースト / 繁殖制御 / 生体アミン / 受容体 / 合成酵素 / 行動学 / 昆虫 / 進化 / 生理学 / 脳・神経
Research Abstract

To compare the regulation systems of reproduction in eusocial hymenopterans, factors regulating the brain levels of dopamine, as a candidate of gonadotoropin, were investigated. In honey bees as a highly eusocial species, dopamine promoted the ovarian development and mating flight behaviors in females and enhanced in the brain levels by food containing richly tyrosine (a precursor of dopamine), especially royal jelly. In male honey bees, on the other hand, dopamine promoted mating flight and enhanced in the brain levels and its receptor gene expression by juvenile hormone. The dopamine regulation system by juvenile hormone could be shared by both sexes in primitively eusocial species (bumble bees) and solitary species (carpenter bees).

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (49 results)

All 2014 2013 2012 2011 Other

All Journal Article (11 results) (of which Peer Reviewed: 8 results) Presentation (24 results) Book (11 results) Remarks (3 results)

  • [Journal Article] Juvenile hormone-dopamine systems for the promotion of flight activity in males of the large carpenter bee Xylocopa appendiculata2013

    • Author(s)
      K. Sasaki, T. Nagao
    • Journal Title

      Naturwiss.

      Volume: 100 Issue: 12 Pages: 1183-1186

    • DOI

      10.1007/s00114-013-1116-4

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neuroendocrine mechanisms underlying regulation of mating flight behaviors in male honey bees (Apis mellifera L.)2013

    • Author(s)
      R. Mezawa, S. Akasaka, T. Nagao, K. Sasaki
    • Journal Title

      Gen. Comp. Endocrinol.

      Volume: 186 Pages: 108-115

    • DOI

      10.1016/j.ygcen.2013.02.039

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Food exchange behavior between multiple founding queens of Polyrhachis moesta (Hymenoptera: Formicidae) changes during hibernation2013

    • Author(s)
      A. Hashimoto, K. Sasaki, S. Koyama, T. Satoh
    • Journal Title

      Applied Entomology and Zoology

      Volume: 48 Issue: 2 Pages: 141-145

    • DOI

      10.1007/s13355-013-0161-y

    • NAID

      40019651156

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of dietary inositol with sucrose stimulation on chewing and swallowing motor patterns in larvae of the silkworm, Bombyx mori2013

    • Author(s)
      K. Sasaki, Y. Ooki, Y. Endo, K. Asaoka
    • Journal Title

      Physiological Entomology

      Volume: 38 Issue: 4 Pages: 326-336

    • DOI

      10.1111/phen.12038

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] アシナガバチの繁殖や性行動を調節する脳内物質2013

    • Author(s)
      佐々木謙
    • Journal Title

      昆虫と自然

      Volume: 48 Pages: 14-17

    • Related Report
      2012 Research-status Report
  • [Journal Article] 生体アミン含有飼料を用いた有用・有害昆虫の行動操作2013

    • Author(s)
      佐々木謙
    • Journal Title

      The New Food Industry

      Volume: 55 Pages: 9-14

    • NAID

      40019614747

    • Related Report
      2012 Research-status Report
  • [Journal Article] Regulation of the brain dopaminergic system by juvenile hormone in honey bee males (Apis mellifera L.)2012

    • Author(s)
      K. Sasaki, S. Akasaka, R. Mezawa, K. Shimada, K. Maekawa
    • Journal Title

      Insect Molecular Biology

      Volume: 21 Issue: 5 Pages: 502-509

    • DOI

      10.1111/j.1365-2583.2012.01153.x

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Caste differences in dopamine-related substances and dopamine supply in the brains of honeybees (Apis mellifera L.)2012

    • Author(s)
      K. Sasaki, S. Matsuyama, K. Harano, T. Nagao
    • Journal Title

      Gen. Comp. Endocrinol.

      Volume: 178 Issue: 1 Pages: 46-53

    • DOI

      10.1016/j.ygcen.2012.04.006

    • Related Report
      2013 Final Research Report 2012 Research-status Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Dopaminergic system as the mechanism underlying personality in a beetle2012

    • Author(s)
      Satoshi Nakayama, Ken Sasaki, Kentarou Matsumura, Zenobia Lewis, Takahisa Miyatake
    • Journal Title

      Journal of Insect Physiology

      Volume: 58 Issue: 5 Pages: 750-755

    • DOI

      10.1016/j.jinsphys.2012.02.011

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Serotonin-induced mate rejection in the female cabbage butterfly, Pieris rapae crucivora2011

    • Author(s)
      Y. Obara, Y. Fukano, K. Watanabe, G. Ozawa, K. Sasaki*
    • Journal Title

      Naturwissenschaften

      Volume: 98 Issue: 11 Pages: 989-993

    • DOI

      10.1007/s00114-011-0847-3

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] 昆虫の咀嚼運動を修飾する外的・内的要因2011

    • Author(s)
      大喜裕二・朝岡潔・佐々木謙
    • Journal Title

      The New Food Industry

      Volume: 53 Pages: 51-58

    • NAID

      40017659599

    • Related Report
      2011 Research-status Report
  • [Presentation] フタモンアシナガバチのワーカーにおける幼若ホルモン-ドーパミン系による繁殖制御機構2014

    • Author(s)
      佐々木謙・浅井一行・土田浩治
    • Organizer
      第58回日本応用動物昆虫学会
    • Place of Presentation
      高知大学(高知市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] アサギマダラ雄の交尾にはアルカロイド摂取による配偶行動の活性化が必須2014

    • Author(s)
      本田計一・松本隼也・佐々木謙・大村尚
    • Organizer
      第58回日本応用動物昆虫学会
    • Place of Presentation
      高知大学(高知市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ドーパミンがネバダオオシロアリの個体間相互作用と兵隊分化に及ぼす影響2014

    • Author(s)
      井上享也・矢口甫・佐々木謙・前川清人
    • Organizer
      第58回日本応用動物昆虫学会
    • Place of Presentation
      高知大学(高知市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] オクトパミン投与がチクシトゲアリ女王の協力行動を減少させる2014

    • Author(s)
      小山哲史・松井伸吾・佐藤俊幸・佐々木謙
    • Organizer
      第58回日本応用動物昆虫学会
    • Place of Presentation
      高知大学(高知市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ハチ目の真社会性種におけるドーパミン制御機構の変遷2013

    • Author(s)
      佐々木謙・目澤龍介・松山周平・長尾隆司
    • Organizer
      第15回日本進化学会
    • Place of Presentation
      筑波大学(茨城県つくば市)
    • Year and Date
      2013-08-28
    • Related Report
      2013 Final Research Report
  • [Presentation] Regulation of the brain dopamine system by juvenile hormone in male honey bees2013

    • Author(s)
      K. Sasaki, R. Mezawa, S. Akasaka, T. Nagao
    • Organizer
      The 35th Annual Meeting of The Japanese Society for Comparative Physiology and Biochemistry
    • Place of Presentation
      イーグレひめじ(兵庫県姫路市)
    • Year and Date
      2013-07-13
    • Related Report
      2013 Final Research Report
  • [Presentation] Regulation of the brain dopamine system by juvenile hormone in male honey bees2013

    • Author(s)
      K. Sasaki, R. Mezawa, S. Akasaka, T. Nagao
    • Organizer
      The 35th Annual Meeting of The Japanese Society for Comparative Physiology and Biochemistry
    • Place of Presentation
      イーグレひめじ(姫路市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ハチ目の真社会性種におけるドーパミン制御機構の変遷2013

    • Author(s)
      佐々木謙・目澤龍介・松山周平・長尾隆司
    • Organizer
      第15回日本進化学会
    • Place of Presentation
      筑波大学(つくば市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ネバダシロアリのソルジャー分化に生体アミンが与える影響2013

    • Author(s)
      井上享也・矢口甫・佐々木謙・前川清人
    • Organizer
      第73回日本昆虫学会
    • Place of Presentation
      北海道大学(札幌市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] チョウ目昆虫幼虫の口器味覚細胞の咀嚼と飲み込み行動における役割について -カイコとテンサンの研究から-2013

    • Author(s)
      朝岡潔・佐々木謙
    • Organizer
      第19回日本野蚕学会
    • Place of Presentation
      東京農工大学(東京都小金井市)
    • Related Report
      2013 Annual Research Report
  • [Presentation] セイヨウミツバチオスの幼若ホルモンによる脳内ドーパミン系の制御2012

    • Author(s)
      佐々木謙・赤坂真也・目澤龍介・嶋田敬介・前川清人
    • Organizer
      第14回日本進化学会
    • Place of Presentation
      東京都立大学(東京都八王子市)
    • Year and Date
      2012-08-21
    • Related Report
      2013 Final Research Report
  • [Presentation] Mechanisms underlying caste differences in the brain levels of dopamine-related substances in adult female honeybees2012

    • Author(s)
      K. Sasaki, S. Matsuyama, K. Harano, T. Nagao
    • Organizer
      The 34th Anuual Meeting of The Japanese Society for Comparative Physiology and Biochemistry
    • Place of Presentation
      総合研究大学院大学(神奈川県葉山町)
    • Year and Date
      2012-07-06
    • Related Report
      2013 Final Research Report
  • [Presentation] 行動の発現・転換・維持に関わる生体アミン2012

    • Author(s)
      佐々木謙
    • Organizer
      第56回日本応用動物昆虫学会
    • Place of Presentation
      近畿大学(奈良県奈良市)
    • Year and Date
      2012-03-28
    • Related Report
      2013 Final Research Report
  • [Presentation] ショ糖存在下におけるイノシトールのカイコ咀嚼・飲み込み運動リズムと味覚応答への作用2012

    • Author(s)
      朝岡潔・佐々木謙・大喜裕二・遠藤祐紀
    • Organizer
      第82回日本蚕糸学会 一般講演
    • Place of Presentation
      九州大学
    • Related Report
      2011 Research-status Report
  • [Presentation] ミツバチ雄の性成熟に伴う生体アミンの動態と幼若ホルモンによる制御2012

    • Author(s)
      目澤龍介・赤坂真也・長尾隆司・佐々木謙
    • Organizer
      第56回日本応用動物昆虫学会 一般講演
    • Place of Presentation
      近畿大学
    • Related Report
      2011 Research-status Report
  • [Presentation] セイヨウミツバチにおける脳内ドーパミン量のカースト差と合成系の制御機構2012

    • Author(s)
      佐々木謙・松山周平・長尾隆司・原野健一
    • Organizer
      第56回日本応用動物昆虫学会 一般講演
    • Place of Presentation
      近畿大学
    • Related Report
      2011 Research-status Report
  • [Presentation] ミツバチワーカーのチロシン経口摂取による脳内ドーパミン・チラミン量の増加と産卵個体化の促進2012

    • Author(s)
      松山周平・高山純一・長尾隆司・佐々木謙
    • Organizer
      第56回日本応用動物昆虫学会 一般講演
    • Place of Presentation
      近畿大学
    • Related Report
      2011 Research-status Report
  • [Presentation] ネバタオオシロアリの初期巣で兵隊分化を引き起こす要因2012

    • Author(s)
      前川清人・矢口甫・佐々木謙
    • Organizer
      第56回日本応用動物昆虫学会 一般講演
    • Place of Presentation
      近畿大学
    • Related Report
      2011 Research-status Report
  • [Presentation] ドーパミン作動系と擬死行動・歩行活動性の遺伝相関2012

    • Author(s)
      中山慧・佐々木謙・渕側太郎・岡田泰和・西優輔・宮竹貴久
    • Organizer
      第56回日本応用動物昆虫学会 小集会(招待講演)
    • Place of Presentation
      近畿大学
    • Related Report
      2011 Research-status Report
  • [Presentation] 行動の発現・転換・維持に関わる生体アミン2012

    • Author(s)
      佐々木謙
    • Organizer
      第56回日本応用動物昆虫学会 小集会(招待講演)
    • Place of Presentation
      近畿大学
    • Related Report
      2011 Research-status Report
  • [Presentation] 社会性ハチ目の繁殖制御とドーパミン調節機構2011

    • Author(s)
      佐々木謙・長尾隆司
    • Organizer
      第13回日本進化学会 一般講演
    • Place of Presentation
      京都大学
    • Related Report
      2011 Research-status Report
  • [Presentation] Mechanisms underlying caste differences in the brain levels of dopamine-related substances in adult female honeybees

    • Author(s)
      K. Sasaki, S. Matsuyama, K. Harano, T. Nagao
    • Organizer
      The 34th Anuual Meeting of The Japanese Society for Comparative Physiology and Biochemistry
    • Place of Presentation
      Hayama
    • Related Report
      2012 Research-status Report
  • [Presentation] セイヨウミツバチオスの幼若ホルモンによる脳内ドーパミン系の制御

    • Author(s)
      佐々木謙・赤坂真也・目澤龍介・嶋田敬介・前川清人
    • Organizer
      第14回日本進化学会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Presentation] ネバタシロアリにおける兵隊型生殖虫の分化機構の解析

    • Author(s)
      橋本裕・佐々木謙・前川清人
    • Organizer
      日本応用動物昆虫学会第57回大会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Book] Sex differences of dopamine control systems associated with reproduction in honey bees, Honeybees: Foraging Behavior, Reproductive Biology and Diseases(分担執筆)2014

    • Author(s)
      K. Sasaki
    • Total Pages
      12
    • Publisher
      NOVA Science Publishers
    • Related Report
      2013 Annual Research Report
  • [Book] Sex differences of dopamine control systems associated with reproduction in honey bees. In : Honeybees : Foraging Behavior, Reproductive Biology and Diseases, (Ed.) C. Malloy2013

    • Author(s)
      K. Sasaki
    • Publisher
      NOVA Science Publishers
    • Related Report
      2013 Final Research Report
  • [Book] Sexual maturation, mating strategies and the neuroendocrinology in social insects. In : Human and Animal Mating : Strategies, Gender Differences and Environmental Influences, (Eds.) M. Nakamura, T. Ito2013

    • Author(s)
      K. Harano, K. Sasaki
    • Publisher
      NOVA Science Publishers
    • Related Report
      2013 Final Research Report
  • [Book] 行動生物学辞典(分担執筆)2013

    • Author(s)
      佐々木謙
    • Total Pages
      5
    • Publisher
      東京化学同人
    • Related Report
      2013 Annual Research Report
  • [Book] Sexual maturation, mating strategies and the neuroendocrinology in social insects, In: Human and Animal Mating: Strategies, Gender Differences and Environmental Influences2013

    • Author(s)
      K. Harano, K. Sasaki
    • Publisher
      NOVA Science Publishers
    • Related Report
      2012 Research-status Report
  • [Book] 研究者が教える動物飼育: フタモンアシナガバチ2012

    • Author(s)
      山崎和久,佐々木謙
    • Publisher
      共立出版
    • Related Report
      2012 Research-status Report
  • [Book] 研究者が教える動物飼育: ミツバチの驚異の視覚情報処理能力と8の字ダンス2012

    • Author(s)
      佐々木謙
    • Publisher
      共立出版
    • Related Report
      2012 Research-status Report
  • [Book] 研究者が教える動物飼育: ヤマヨツボシオオアリ2012

    • Author(s)
      佐々木謙
    • Publisher
      共立出版
    • Related Report
      2012 Research-status Report
  • [Book] Regulation of reproductive states and control of sex of eggs by reproductive females in eusocial Hymenoptera, In : Social Insect : Structure, Function, Behavior, (Ed.) E. M. Stewart2011

    • Author(s)
      K. Sasaki
    • Publisher
      NOVA Science Publishers
    • Related Report
      2013 Final Research Report
  • [Book] Social Insect: Structure, Function, Behavior, (Ed.) Emily M. Stewart, chapter 3, Regulation of reproductive states and control of sex of eggs by reproductive females in eusocial Hymenoptera2011

    • Author(s)
      K. Sasaki
    • Total Pages
      21
    • Publisher
      NOVA Science Publishers
    • Related Report
      2011 Research-status Report
  • [Book] Social Insect: Structure, Function, Behavior, (Ed.) Emily M. Stewart, chapter 10, Biogenic amines and division of reproduction in social insects2011

    • Author(s)
      K. Sasaki
    • Total Pages
      25
    • Publisher
      NOVA Science Publishers
    • Related Report
      2011 Research-status Report
  • [Remarks] Researchmapホームページ

    • URL

      http://researchmap.jp/read0054468

    • Related Report
      2013 Final Research Report
  • [Remarks] 研究業績紹介ページ(英文)-ResearchGate

    • URL

      https://www.researchgate.net/profile/Ken_Sasaki2?ev=prf_highl

    • Related Report
      2013 Annual Research Report
  • [Remarks] 研究業績紹介ページ-Research map

    • URL

      http://researchmap.jp/read0054468

    • Related Report
      2013 Annual Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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