Research Project
Grant-in-Aid for Young Scientists (B)
RIG-I is a sensor protein that specifically recognize viral RNA and induce early immunity . In the absence of virus RIG-I forms resting form not to induce antiviral activities. Because, those activities are also toxic for our body. I performed functional analysis of sensor protein RIG-I and identified suppression domain of RIG-I that controls RIG-I activation. From this result I suggested the mechanism that how RIG-I is self-controlled its activity .
All 2012 2011 Other
All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results) Book (2 results) Remarks (1 results)
Biochem. Biophys. Res. Commun
Volume: 415 (1) Pages: 75-81
Biochemical and Biophysical Research Communications
Volume: 415 Issue: 1 Pages: 75-81
10.1016/j.bbrc.2011.10.015
http://www.virus.kyoto-u.ac.jp/Lab/bunshiiden2012/Japanese/99_blank.html