| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Research Abstract |
Bacterial nitric oxide reductase is a membrane integral enzyme that catalyzes the reduction of nitric oxide to nitrous oxide during the nitrate respiration, an anaerobic respiration of facultative anaerobic organisms. In the present study, I determined the crystal structure of nitric oxide reductase from Pseudomonas aeruginosa in the fully reduced state and revealed that no obvious structural changes were induced including active site upon reduction of all metal sites
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