| Project/Area Number |
23770195
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biophysics
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| Research Institution | Japan Synchrotron Radiation Research Institute |
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Principal Investigator |
MIZUNO Nobuhiro 公益財団法人高輝度光科学研究センター, 利用研究促進部門, 研究員 (90378844)
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | 放射光X線結晶構造解析 / タンパク質X線結晶解析 / タンパク質構造解析 |
|---|
| Research Abstract |
In this research, in order to calculate precise electron density, I tried to develop accurate measurement methods of low resolution diffraction data and visualization methods of solvent area structure without error. I constructed a measurement system of precise low resolution data at SPring-8 with high flux X-ray. Los-free diffraction data in low resolution area could be obtained in this system. Heavy atoms, PbEDTA or Xe, for visualization of solvent area could successfully soaked in protein crystal.
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