The epigenetic roles of DNA damage repair in euchromatin
| Project/Area Number |
23770205
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Molecular biology
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | エピジェネティクス / DNA修復 / ヒストン修飾 / ヒストンメチル化 / ヒストンアセチル化 |
|---|
| Research Abstract |
It has been reported that the efficient DNA damage response in heterochromatin requires histone H3 K9 methylation. However, in this study, it issuggested that H3 K9 methylation is not required for damage response signaling in euchromatin. Furthermore, the other histone modification is indicated to be involved in this regulation.
|
Report
(3 results)
Research Products
(4 results)
