Research Project
Grant-in-Aid for Young Scientists (B)
Earlier studies suggested that an extensive heterochromatin formation takes place throughout the genome in post-implantation mouse embryos (heterochromatin: condensed chromosome regions with transcriptionally inactive genes). To explore its significance, we set out to identify genes involved in this heterochromatinization process. A list of candidate genes was generated and we asked whether suppression of any of these candidate genes could disrupt heterochromatin formation. This led to the identification of four novel genes involved in this process.
All 2013 2012 2011 Other
All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (6 results) (of which Invited: 2 results)
Developmental Cell
Volume: 24 Pages: 635-648
Dev Cell
Volume: 24 Issue: 6 Pages: 635-648
10.1016/j.devcel.2013.02.009
PLoS One
Volume: 6
PLoS Computational Biology
Volume: 7
Nature Protocols
Volume: 6 Pages: 870-895
Volume: 7 Issue: 10 Pages: e1002225-e1002225
10.1371/journal.pcbi.1002225
Volume: 6 Issue: 11 Pages: e27413-e27413
10.1371/journal.pone.0027413