Analysis of amechanism for embryonic turning and organ looping.
| Project/Area Number |
23770246
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Developmental biology
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 器官形成 / 心臓 / 腸 / ルーピング / ターニング / マウス / 左右 / 非対称 / 臓器 / ねじれ / BMP / Pitx2 |
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| Research Abstract |
We revealed that asymmetric BMP signal play an important role to make embryonic turning asymmetrically in the Lateral Plate Mesoderm of mouse. Asymmetric BMP signal is caused by asymmetric expressions of BMP 2,4,5.
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Report
(3 results)
Research Products
(4 results)
