Analysis of amechanism for embryonic turning and organ looping.

Research Project

Project/Area Number	23770246
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Developmental biology
Research Institution	Osaka University
Principal Investigator	NAKAMURA Tetsuya 大阪大学, 生命機能研究科, 助教 (70506766)
Project Period (FY)	2011 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000) Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000) Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords	器官形成 / 心臓 / 腸 / ルーピング / ターニング / マウス / 左右 / 非対称 / 臓器 / ねじれ / BMP / Pitx2
Research Abstract	We revealed that asymmetric BMP signal play an important role to make embryonic turning asymmetrically in the Lateral Plate Mesoderm of mouse. Asymmetric BMP signal is caused by asymmetric expressions of BMP 2,4,5.

Report

(3 results)