Glycome analysis in Vertebrate Embryogenesis

• Project/Area Number: 23770267
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Developmental biology
• Research Institution: National Institute of Advanced Industrial Science and Technology
• Principal Investigator: ONUMA Yasuko 独立行政法人産業技術総合研究所, 幹細胞工学研究センター, 主任研究員 (90431824)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 器官形成 / 発生・分化 / 動物 / 細胞・組織 / 両生類 / 糖鎖

Research Abstract

T o investigate stage-specific glycomes in Xenopus laevis embryos, a lectin microarray system was used. Unsupervised cluster analysis of lectin microarray dataindicated that glycan profiles changed sequentially during development. Nine lectin probes showe

Research Products

• [Journal Article] A Lectin-Based Glycomic Approach to Identify Characteristic Features of Xenopus Embryogenesis (2013)
  • Author(s): Yasuko Onuma、Hiroaki Tateno、Shingo Tsuji、Jun Hirabayashi、Yuzuru Ito、Makoto Asashima
  • Journal Title: PLoS One 誌 Volume: 8 Issue: 2 Pages: e56581-e56581
  • DOI: 10.1371/journal.pone.0056581
  • Peer Reviewed
• [Presentation] Xenopus 胚のグライコーム解析へのレクチンの利用 (2013)
  • Author(s): 小沼泰子
  • Organizer: 第12回産総研・産技連 LS-BT 合同研究発表会
  • Place of Presentation: 独立行政法人産業技術総合研究所(茨城県)
  • Year and Date: 2013-02-05
• [Presentation] A lectin-based glycomic approach to Xenopus embryogenesis (2012)
  • Author(s): 小沼泰子
  • Organizer: 14th International Xenopus Conference
  • Place of Presentation: the Belambra Club (Giens、France)
  • Year and Date: 2012-09-11
• [Presentation] A lectin-based glycomic approach to Xenopus embryogenesis
  • Author(s): Yasuko Onuma
  • Organizer: 14th International Xenopus Conference
  • Place of Presentation: Giens, France
• [Presentation] Xenopus 胚のグライコーム解析へのレクチンの利用
  • Author(s): 小沼泰子
  • Organizer: 第12回産総研・産技連LS-BT合同研究発表会
  • Place of Presentation: 茨城県つくば市