| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Research Abstract |
LitR is an adenosyl Bl2-dependent light-sensitive MerR family transcriptional regulator,and litRhomologues are widely distributed among the Phylogenetically diverse genera of non-Phototrophic bacteria, including gram-positive and gram-negative bacteria. Our study on the function and role of LitR from Thermus and Bacillus revealed that LitrR is a central regulator of the light-inducible carotenoids production in both strains. Furthermore,we showed that LitR protein is an adenosyl B12-dependent light-sensitive regulaor in vivo experiment. We also revealed that LOV type photoreceptor is involved in the LitR-dependent transcriptional regulation in Pseudomonas.
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