Studies on a microbial function induced by light
| Project/Area Number |
23780093
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied microbiology
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| Research Institution | Nihon University |
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Principal Investigator |
TAKANO Hideaki 日本大学, 生物資源科学部, 助教 (50385994)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | Photo-response / Transcriptional regulation / LitR / MerR family / Cobalamin / Streptomyces coelicolor / Thermus thermophilus / Pseudomonas putida / 光受容体 / ビタミンB12 / カロテノイド / 光センサー / コエンザイムB12 |
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| Research Abstract |
LitR is an adenosyl Bl2-dependent light-sensitive MerR family transcriptional regulator,and litRhomologues are widely distributed among the Phylogenetically diverse genera of non-Phototrophic bacteria, including gram-positive and gram-negative bacteria. Our study on the function and role of LitR from Thermus and Bacillus revealed that LitrR is a central regulator of the light-inducible carotenoids production in both strains. Furthermore,we showed that LitR protein is an adenosyl B12-dependent light-sensitive regulaor in vivo experiment. We also revealed that LOV type photoreceptor is involved in the LitR-dependent transcriptional regulation in Pseudomonas.
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Report
(3 results)
Research Products
(41 results)
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[Journal Article] Involvement of CarA/LitR and CRP/FNR family transcriptional regulators in light-induced carotenoid production in Thermus thermophilus2011
Author(s)
Takano H, Kondo M, Usui N, Usui T, Ohzeki H, Yamazaki R, Washioka M, Nakamura A, Hoshino T, Hakamata W, Beppu T, Ueda K.
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Journal Title
J Bacteriol
Volume: 193
Pages: 2451-2459
Related Report
Peer Reviewed
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