| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
A part of phenolic constituents of foods have been considered to play an important role on preventing lifestyle-related diseases or lowering disease risks. However, the phenolic compounds such as polyphenols are known to undergo circulation and excretion as their conjugated form after the hepatic and intestinal metabolic transformation in our body. Whether the conjugation of these compounds by sulfation may enhance their physiological functions, remains unclear. The current study aimed to investigate whether a sulfated form of certain phenolic compound could demonstrate any biological functions as a model. Antioxidant analyses revealed that the sulfated metabolite was capable of showing suppressive effect rather than its unconjugated form upon a reactive oxygen generation system in vitro.
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