| Project/Area Number |
23780280
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied animal science
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| Research Institution | Kinki University |
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Principal Investigator |
AMANO Tomoko 近畿大学, 生物理工学部, 講師 (60388585)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 時計遺伝子 / 卵巣機能 / 卵巣 / 性周期 / 排卵 / 時計遺伝子群 / マウス |
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| Research Abstract |
To identify the genes of which transcriptions are regulated by the circadian genes (Clock controlled genes: CCGs) in the mouse ovaries, we compared the gene expression in the ovaries of the mice bearing deficiencies of the circadian genes, Clock mutant mice and Per1/Per2 knockout mice, with that of the ovaries of wild type mice by microarray analysis. As a result, we detected some genes known to regulate reproductive ability in females including StAR. We will examine the interaction of the circadian genes on the promoter region of those genes in our next experiments.
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