| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Research Abstract |
It has been known that good relationship between infant and mother ensures adequate development of offspring’s sociality. We focused on oxytocin neural system in infant mice to understand the underlying physiological mechanism. As results, the expression of oxytocin receptor was grater in several regions such as cingulate cortex in infant mice as compared with adults. It was also indicated that the oxytocin release to cingulate cortex was upregulated by existence of mother, and infant specific inhibition of oxytocin signaling on cingulate cortex induced the alteration of social cognitive ability and social behaviors in adulthood. These are crucial clues to understand the mechanism for development of sociality.
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