The study for the development mechanism of sociality according to an infant specific oxytocin neural system
| Project/Area Number |
23780301
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Azabu University |
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Principal Investigator |
MOGI Kazutaka 麻布大学, 獣医学部, 准教授 (50347308)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 社会行動 / 社会認知 / 発達 / 母子関係 / オキシトシン / 帯状回皮質 |
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| Research Abstract |
It has been known that good relationship between infant and mother ensures adequate development of offspring’s sociality. We focused on oxytocin neural system in infant mice to understand the underlying physiological mechanism. As results, the expression of oxytocin receptor was grater in several regions such as cingulate cortex in infant mice as compared with adults. It was also indicated that the oxytocin release to cingulate cortex was upregulated by existence of mother, and infant specific inhibition of oxytocin signaling on cingulate cortex induced the alteration of social cognitive ability and social behaviors in adulthood. These are crucial clues to understand the mechanism for development of sociality.
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Report
(3 results)
Research Products
(28 results)
